A Conspiracy Revealed: The Divine Conspiracy (by Willard, D.)

When I (Paul) first obtained Willard’s book The Divine Conspiracy, I could not help but notice the attractive painting of two ripe plums on the cover. “What a nice touch,” I thought. “A fine painting—a little color, artistic shapes, and angles. It grabs my attention.” But after feasting upon the wisdom behind this finely decorated cover, I came to appreci-ate the symbolism of fruit on the tree. In The Divine Conspiracy, Willard gives maturing Christians an opportunity to reconceptualize their place in the kingdom of heaven. As a fitting completion to Willard’s wisdom-filled “trilogy on the spiritual life” (p. xvii), The Divine Conspiracy stresses discipleship to Jesus as the heart of the gospel message. He challenges the reader to set aside common misconceptions, what he calls “consumer Christianity” and “bumper-sticker faith,” to reclaim one’s present position in “the kingdom among us.

Natural nitrogen-15 abundance of soil and plant samples

Includes bibliographical references (page 50).Nitrogen isotope analysis of total soil N and soil-derived nitrate for nine selected Chernozemic and Luvisolic Ap horizons showed mean δa15N values based on atmospheric abundance of 8.8. Luvisolic soils were characterized by a relatively low level of the heavier isotope. Isotope enrichment of the total N reached a maximum in the lower B horizon. Subsoil nitrate (180-cm depth) had a δa15N value 1/3 that of the Ap horizon. The δa15N of subsurface soil horizons containing residual fertilizer N were low (−5.2) compared to the surface horizon (7.0). The δa15N of NH4-N in commercial fertilizers is close to that of atmospheric-N whereas the NO3-N has higher values. The data suggest that variations in δ15N abundance between horizons of the same soil, or between different soils, may be of real use in evaluating stresses which have been placed in the nitrogen cycle due to man's activities in the past. Similarly, differences in 15N abundance of soil, legume and air samples may provide an integrated estimation of symbiotic nitrogen fixation under field conditions. More detailed understanding of biological and other processes which control the N isotope concentrations must be obtained before the data reported can be further interpreted

A 3D <i>in vitro</i> model reveals differences in the astrocyte response elicited by potential stem cell therapies for CNS injury.

Aim: This study aimed to develop a 3D culture model to test the extent to which transplanted stem cells modulate astrocyte reactivity, where exacerbated glial cell activation could be detrimental to CNS repair success. Materials & methods: The reactivity of rat astrocytes to bone marrow mesenchymal stem cells, neural crest stem cells (NCSCs) and differentiated adipose-derived stem cells was assessed after 5 days. Schwann cells were used as a positive control. Results: NCSCs and differentiated Schwann cell-like adipose-derived stem cells did not increase astrocyte reactivity. Highly reactive responses to bone marrow mesenchymal stem cells and Schwann cells were equivalent. Conclusion: This approach can screen therapeutic cells prior to in vivo testing, allowing cells likely to trigger a substantial astrocyte response to be identified at an early stage. NCSCs and differentiated Schwann cell-like adipose-derived stem cells may be useful in treating CNS damage without increasing astrogliosis

Spiritual Experiences of Adults with Advanced Cancer in Outpatient Clinical Settings

Context Adults who have advanced cancer experience distress, and many use religion and spirituality to cope. Research on the spiritual experiences of advanced cancer patients will help guide the provision of high-quality spiritual care. Objectives To qualitatively describe advanced cancer patients’ spiritual experiences of illness. Methods We conducted semi-structured qualitative interviews at a single cancer center with 21 patients with stage IV solid malignancies who had a prognosis of less than 12 months, as estimated by each patient’s medical oncologist. Five investigators conducted a thematic analysis of the transcribed interviews. Results We found 31 patients who were eligible for enrollment, and 21 (67.7%) participated in interviews to thematic saturation. Using a thematic-analysis approach, five major themes emerged. Relationships with family and friends was the most important theme among all 21 patients irrespective of their religious or spiritual identity. Relationship with God and faith community was frequently identified by those who considered themselves spiritually religious. Cancer often led to reflection about the meaning of life and the nature of existential suffering Patients addressed the extent to which identity was changed or maintained through the cancer experience, and some expressed acceptance as a way of coping with illness. Conclusions Spiritual care for dying cancer patients should always include the exploration of relationships with family and friends, as well as God and faith community for some patients. Relationships with family, friends, and God can be a source of strength for many. Making meaning, addressing identity concerns, supporting acceptance as a resource for coping with illness, and acknowledging existential suffering will often arise for these patients

Biochemical Systematics of Notothenioid Fishes from Antarctica

Genetic variation at 30 protein-coding loci was examined in seven forms of notothenioid fishes from Antarctica. Multilocus heterozygosity varied from 0.018 to 0.078 across taxa. An analysis of the allozyme data revealed the probable existence of an unrecognized cryptic species within Trematomu5 bemacchii. Pagothenia borchgrevinki is as closely related to some species of Trematomus as are some species of Trematomus to each other. Speciation among the species of Trematomus and Pagothenia appears to have taken place primarily after the separation of Antarctica from Australia

Social correlates of mental health in gastrointestinal cancer patients and their family caregivers: Exploring the role of loneliness

Purpose The present study examined the degree to which loneliness mediated the influence of negative (social constraints) and positive (emotional support) relationship qualities on the global mental health of advanced gastrointestinal (GI) cancer patients and their family caregivers. Methods Fifty patient-caregiver dyads completed measures assessing social constraints (e.g., avoidance, criticism) from the other dyad members, emotional support from others, loneliness, and global mental health. Structural equation modeling was used to examine individual models, and Actor-Partner Interdependence Mediation Modeling was used to examine dyadic associations. Results Individual path analyses for patients and caregivers demonstrated that emotional support had a significant indirect effect on mental health through loneliness (Bs = 0.32 and 0.30, respectively), but no associations were found between social constraints and mental health. In dyadic analyses, participants’ loneliness and mental health were not significantly related to their partner’s emotional support, loneliness, or mental health (Bs = − 0.18 to 0.18). Conclusions Findings suggest that for advanced GI cancer patients and caregivers, emotional support from others alleviates feelings of loneliness, which may lead to better mental health. However, the benefits of emotional support appear to be primarily intrapersonal rather than interpersonal in nature. Additionally, participants endorsed low levels of social constraints, which might explain their lack of relation to loneliness and mental health. Continued examination of interdependence in social processes between cancer patients and caregivers will inform intervention development

Addressing Personal Barriers to Advance Care Planning: Qualitative Investigation of a Mindfulness-Based Intervention for Adults with Cancer and Their Family Caregivers

Objective Advance care planning (ACP) increases quality of life and satisfaction with care for those with cancer and their families, yet these important conversations often do not occur. Barriers include patients’ and families’ emotional responses to cancer, such as anxiety and sadness, which can lead to avoidance of discussing illness-related topics such as ACP. Interventions that address psychological barriers to ACP are needed. The purpose of this study was to explore the effects of a mindfulness intervention designed to cultivate patient and caregiver emotional and relational capacity to respond to the challenges of cancer with greater ease, potentially decreasing psychological barriers to ACP and enhancing ACP engagement. Method The Mindfully Optimizing Delivery of End-of-Life (MODEL) Care intervention provided 12 hours of experiential training to two cohorts of six to seven adults with advanced-stage cancer and their family caregivers (n = 13 dyads). Training included mindfulness practices, mindful communication skills development, and information about ACP. Patient and caregiver experiences of the MODEL Care program were assessed using semistructured interviews administered immediately postintervention and open-ended survey questions delivered immediately and at 4 weeks postintervention. Responses were analyzed using qualitative methods. Result Four salient themes were identified. Patients and caregivers reported the intervention (1) enhanced adaptive coping practices, (2) lowered emotional reactivity, (3) strengthened relationships, and (4) improved communication, including communication about their disease. Significance of results The MODEL Care intervention enhanced patient and caregiver capacity to respond to the emotional challenges that often accompany advanced cancer and decreased patient and caregiver psychological barriers to ACP

Optically opaque color-flavor locked phase inside compact stars

The contribution of thermally excited electron-positron pairs to the bulk properties of the color-flavor locked quark phase inside compact stars is examined. The presence of these pairs causes the photon mean free path to be much smaller than a typical core radius ($R_0 \simeq 1$ km) for all temperatures above 25 keV so that the photon contribution to the thermal conductivity is much smaller than that of the Nambu-Goldstone bosons. We also find that the electrons and positrons dominate the electrical conductivity, while their contributions to the total thermal energy is negligible.Comment: 3 pages, 2 figures. Published versio