3,253 research outputs found

    The Coddling of the American Worker\u27s Mind: The Anti-Free Speech Nature of Popular Labor Law Reforms

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    As the nation enters an era in which a new presidential administration will likely push such labor law reforms, it is worth considering whether transparently anti-free speech reform measures make sense for the future of labor policy and law. This Article argues that they do not. Because employee free choice is furthered, not diminished, by hearing both sides of an issue, American workers should have the opportunity to hear and evaluate employer speech in the course of union campaigns. Only then can employees make an informed decision about their workplace future. In the end, freedom of speech furthers employee freedom of choice—the NLRA’s statutory goal in union elections. For these reasons, many labor law reform proposals should be rejected and seen for what they are: an attempt to suppress a particular viewpoint in furtherance of unionization, without regard for employee freedom of choice or a free and fair debate. This abstract has been taken from the author\u27s introduction

    The Criminalization of HIV/AIDS

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    How has Canadian law evolved in terms of our understanding of sexual assault and HIV/AIDS? We reviewed Canadian criminal cases that involved those who didn’t disclose their HIV/AIDS status prior to sexual activity. We also examined current and empirically valid medical information regarding transmission rates to illustrate the evolving knowledge of the HIV/AIDS viruses

    Starspot-induced optical and infrared radial velocity variability in T Tauri star Hubble 4

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    We report optical (6150 Ang) and K-band (2.3 micron) radial velocities obtained over two years for the pre-main sequence weak-lined T Tauri star Hubble I 4. We detect periodic and near-sinusoidal radial velocity variations at both wavelengths, with a semi-amplitude of 1395\pm94 m/s in the optical and 365\pm80 m/s in the infrared. The lower velocity amplitude at the longer wavelength, combined with bisector analysis and spot modeling, indicates that there are large, cool spots on the stellar surface that are causing the radial velocity modulation. The radial velocities maintain phase coherence over hundreds of days suggesting that the starspots are long-lived. This is one of the first active stars where the spot-induced velocity modulation has been resolved in the infrared.Comment: Accepted for publication in The Astrophysical Journa

    Identification of a Defensin from the Hemolymph of the American Dog Tick, Dermacentor variabilis

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    Hemolymph from partially fed virgin Dermacentor variabilis females was collected following Borrelia burgdorferi challenge and assayed for antimicrobial activity against Bacillus subtilis and B. burgdorferi. A small inducible cationic peptide was identified by SDS-PAGE in the hemolymph of these ticks as early as 1h post challenge. Following purification by a three-step procedure involving sequential SepPak elution, reversed phase high performance liquid chromatography (RP-HPLC) and gel electrophoresis, the yield of the active peptide was approximately 0.1% of the total protein in the hemolymph plasma. The molecular weight, 4.2kDa, was determined by MALDI-TOF mass spectrometry. N-terminal sequencing by the Edman degradation method gave a sequence for the first 30 amino acids as: G-F-G-C-P-L-N-Q-G-A-C-H-N-H-C-R-S-I-(R)-(R)-(R)-G-G-Y-C-S-Q-I-I-K. A computer search of databases showed that the peptide had 83% similarity to a defensin found in a scorpion. This is the first report of a defensin from a tick. The peptide was stable at least up to 70 degree C. Although the tick defensin alone was not immediately effective against B. burgdorferi, tick defensin plus lysozyme killed more than 65% of cultured B. burgdorferi within 1h

    Response of the Tick Dermacentor variabilis (Acari: Ixodidae) to Hemocoelic Inoculation of Borrelia burgdorferi (Spirochetales)

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    When Borrelia burgdorferi B31 low passage strain spirochetes were directly injected into the hemocoel of Dermacentor variabilis(Say) females, the bacteria were cleared from the hemocoel within \u3c 24 h. Viable spirochetes were not found in hemolymph, salivary gland, or ovary tissues by subculturing or by IFA. The hemocyte population increased ≈6 times within the first 6 h after inoculation compared with the uninoculated controls. In contrast, the soluble total hemolymph protein content decreased inversely with the increase in hemocytes. Borreliacidal activity was demonstrated with cell-free hemolymph from D. variabilis. In vitro antimicrobial assays using hemolymph from borrelia-challenged and nonchallenged ticks resulted in 72% spirochete reductions compared with only 11.5%, respectively, within 1 h. Additional evidence of induced antimicrobial hemolymph protein activity was demonstrated by SDS-PAGE, which revealed upregulation of a lysozyme-like peptide (≈ 15 kDa) (22% increase) and the induction of a ≈ 5.8 kDa peptide in the B. burgdorferi-challenged ticks. In contrast with the nonvector borne Bacillus subtilis, D. variabilis presented a rapid and robust response to challenge with cultured B. burgdorferi spirochetes and lead to their early elimination. The role of the tick immune system, including possible differences between vector and nonvector ticks, in determining the success of invasive bacteria is discussed
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