274 research outputs found

    John Wilmot to Jim, 27 September 1960

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    Professional correspondenc

    Land Grant Application- Croxford, John (Newburgh)

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    Land grant application submitted to the Maine Land Office on behalf of John Croxford for service in the Revolutionary War, by their widow Wilmot.https://digitalmaine.com/revolutionary_war_me_land_office/1223/thumbnail.jp

    Voices of divergence: resistance, contestation and the shaping of Namibia’s teacher education, 1990- 2010

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    This paper reports on an aspect of a broader study that investigated teacher educators’ uptake of learner-centred pedagogy in post-apartheid Namibia. The paper shares part of the study that illuminated the path traversed by Namibian teacher education policy from 1990 to 2010, two decades into the country’s post-apartheid self-rule. It argues that, far from being smooth sailing, teacher education reform in post-apartheid Namibia has been characterised by severe turbulence with divergent forces wrestling over the philosophical and epistemological orientations of the new teacher education. The paper concludes that these forces, voices of divergence, criticisms, resistance or contestations were a significant feature that helped define and shape post-1990 teacher education for basic education to its present-day state

    A Successful Component Architecture for Interoperable and Evolvable Ground Data Systems

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    The National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC) has adopted an open architecture approach for satellite control centers and is now realizing benefits beyond those originally envisioned. The Goddard Mission Services Evolution Center (GMSEC) architecture utilizes standardized interfaces and a middleware software bus to allow functional components to be easily integrated. This paper presents the GMSEC architectural goals and concepts, the capabilities enabled and the benefits realized by adopting this framework approach. NASA experiences with applying the GMSEC architecture on multiple missions are discussed. The paper concludes with a summary of lessons learned, future directions for GMSEC and the possible applications beyond NASA GSFC

    Genetic variation of rougheye rockfish (Sebastes aleutianus) and shortraker rockfish (S. borealis) inferred from allozymes

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    Rougheye rockfish (Sebastes aleutianus) and shortraker rockfish (Sebastes borealis) were collected from the Washington coast, the Gulf of Alaska, the southern Bering Sea, and the eastern Kamchatka coast of Russia (areas encompassing most of their geographic distribution) for population genetic analyses. Using starch gel electrophoresis, we analyzed 1027 rougheye rockfish and 615 shortraker rockfish for variation at 29 proteincoding loci. No genetic heterogeneity was found among shortraker rockfish throughout the sampled regions, although shortraker in the Aleutian Islands region, captured at deeper depths, were found to be significantly smaller in size than the shortraker caught in shallower waters from Southeast Alaska. Genetic analysis of the rougheye rockfish revealed two evolutionary lineages that exist in sympatry with little or no gene f low between them. When analyzed as two distinct species, neither lineage exhibited heterogeneity among regions. Sebastes aleutianus seems to inhabit waters throughout the Gulf of Alaska and more southern waters, whereas S. sp. cf. aleutianus inhabits waters throughout the Gulf of Alaska, Aleutian Islands, and Asia. The distribution of the two rougheye rockfish lineages may be related to depth where they are sympatric. The paler color morph, S. aleutianus, is found more abundantly in shallower waters and the darker color morph, Sebastes sp. cf. aleutianus, inhabits deeper waters. Sebastes sp. cf. aleutianus, also exhibited a significantly higher prevalence of two parasites, N. robusta and T. trituba, than did Sebastes aleutianus, in the 2001 samples, indicating a possible difference in habitat and (or) resource use between the two lineages

    Medical dispensaries in Warwickshire : their place in local health care, 1820 –1880

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    This thesis offers a fresh view of the under-explored area of nineteenth- century dispensaries, outpatient medical charities that served the ‘sick poor’. Most were founded by members of local elites, in varying combinations with medical practitioners. Warwickshire was selected as the study area as a varied and medium-sized county, Chapter 1 summarising its history and geography. The research was based on local case studies in different towns: Birmingham and Coventry as growing industrial centres, and Stratford-on-Avon and Southam as smaller towns covering largely semi-rural populations. Chapter 2 starts with two early foundations (c.1790) in Birmingham and Coventry but concentrates on the years of expansion during 1820-60. Chapter 3 turns to medical needs in the countryside, initially addressing Stratford-on-Avon, both its dispensary and the later infirmary. In Chapter 5, Southam is considered as the location for the first ‘self-supporting’ or provident dispensary in 1823. Both this and its imitators drew largely on mutual funding from regular payments by working-class users; the Chapter explores reasons for institutional success or failure. The Coventry provident dispensary was contested at its birth in 1831, but attracted many members, late in the century again provoking local professional opposition. The activities of dispensaries included the study and teaching of common diseases, and the early medical school in Birmingham relied heavily on such teaching. Some dispensary staff were active in writing and editing, and Chapter 4 analyses two individual journalistic careers. The thesis also considers wider civic and cultural activities, including reporting for public sanitary commissions in the 1840s and 1850s. The final Chapter (6) considers challenges for dispensaries late in the century, namely increased workload, renewed contestation in Coventry, and pressures from both medical officers and working people for increased recognition or influence. The study explores such tensions, together with their attempted resolution through organisational changes and representation on governing bodies

    Voices of divergence: resistance, contestation and the shaping of Namibia’s teacher education, 1990- 2010

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    This paper reports on an aspect of a broader study that investigated teacher educators’ uptake of learner-centred pedagogy in post-apartheid Namibia. The paper shares part of the study that illuminated the path traversed by Namibian teacher education policy from 1990 to 2010, two decades into the country’s post-apartheid self-rule. It argues that, far from being smooth sailing, teacher education reform in post-apartheid Namibia has been characterised by severe turbulence with divergent forces wrestling over the philosophical and epistemological orientations of the new teacher education. The paper concludes that these forces, voices of divergence, criticisms, resistance or contestations were a significant feature that helped define and shape post-1990 teacher education for basic education to its present-day state

    Brett T. Wilmot and John Witte, Jr. God’s Joust, God’s Justice; Conversations in Religion and Theology (17 October 2007)

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    This Article includes Brett T. Wilmot's review of John Witte, Jr.'s work, God's Joust, God's Justice, along with the author's response to this review

    Comparison of drug delivery with autoinjector versus manual prefilled syringe and between three different autoinjector devices administered in pig thigh

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    Parenteral routes of drug administration are often selected to optimize actual dose of drug delivered, assure high bioavailability, bypass first-pass metabolism or harsh gastrointestinal environments, as well as maximize the speed of onset. Intramuscular (IM) delivery can be preferred to intravenous delivery when initiating intravenous access is difficult or impossible. Drugs can be injected intramuscularly using a syringe or an automated delivery device (autoinjector). Investigation into the IM delivery dynamics of these methods may guide further improvements in the performance of injection technologies. Two porcine model studies were conducted to compare differences in dispersion of injectate volume for different methods of IM drug administration. The first study compared the differences in the degree of dispersion and uptake of injectate following the use of a manual syringe and an autoinjector. The second study compared the spatial spread of the injected formulation, or dispersion volume, and uptake of injectate following the use of five different autoinjectors (EpiPen® [0.3 mL], EpiPen® Jr [0.3 mL], Twinject® [0.15 mL, 0.3 mL], and Anapen® 300 [0.3 mL]) with varying needle length, needle gauge, and force applied to the plunger. In the first study, the autoinjector provided higher peak volumes of injectate, indicating a greater degree of dispersion, compared with manual syringe delivery. In the second study, EpiPen autoinjectors resulted in larger dispersion volumes and higher initial dispersion ratios, which decreased rapidly over time, suggesting a greater rate of uptake of injectate than the other autoinjectors. The differences in dispersion and uptake of injectate are likely the result of different functional characteristics of the delivery systems. Both studies demonstrate that the functional characteristics of the method for delivering IM injections impact the dispersion and uptake of the material injected, which could significantly affect the pharmacokinetics and, ultimately, the effectiveness of the drug
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