Post-metamorphic fluid infiltration into granulites from the Adirondack Mountains, USA

Post-metamorphic effects in the anorthosites of the Adirondacks, New York were described. Calcite-chlorite-sericite assemblages occur as veins, in disseminated form and as clots, and document retrograde fluid infiltration. These features are associated with late-state CO2-rich fluid inclusions. Stable isotope analyses of calcites indicates that the retrograde fluids interacted with meta-igneous and supracrustal lithologies, but the precise timing of the retrogression is as yet unknown

Valuing remnant vegetation in Central Queensland using choice modelling

In the Desert Uplands region of Central Queensland, many pastoralists are clearing vegetation in order to improve cattle grazing production. A choice modelling study was undertaken to provide estimates of the benefits of retaining remnant vegetation that are appropriate for inclusion in a cost benefit analysis of tighter clearing restrictions. Attributes included in the choice model were reductions in the population size of non‐threatened species, the number of endangered species lost to the region, and changes in regional income and employment. A nested logit model was used to model the data in order to avoid violations of the independence of irrelevant alternatives condition. The estimated benefits are reported for several tree clearing policy regimes that are more stringent than those currently applied.Resource /Energy Economics and Policy,

Missouri bond No. 32 for $1000. Signed by Sterling Price, governor, April 15, 1853.

Missouri bond No. 32 for $1000, redeemable 30 years thereafter. Signed by Governor Sterling Price and Secretary of State John M. Richardson. Registered on April 15th, 1853.https://digitalcommons.wofford.edu/littlejohnmss/1250/thumbnail.jp

Segregation and linkage analysis for longitudinal measurements of a quantitative trait

We present a method for using slopes and intercepts from a linear regression of a quantitative trait as outcomes in segregation and linkage analyses. We apply the method to the analysis of longitudinal systolic blood pressure (SBP) data from the Framingham Heart Study. A first-stage linear model was fit to each subject's SBP measurements to estimate both their slope over time and an intercept, the latter scaled to represent the mean SBP at the average observed age (53.7 years). The subject-specific intercepts and slopes were then analyzed using segregation and linkage analysis. We describe a method for using the standard errors of the first-stage intercepts and slopes as weights in the genetic analyses. For the intercepts, we found significant evidence of a Mendelian gene in segregation analysis and suggestive linkage results (with LOD scores ≥ 1.5) for specific markers on chromosomes 1, 3, 5, 9, 10, and 17. For the slopes, however, the data did not support a Mendelian model, and thus no formal linkage analyses were conducted

Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro

BACKGROUND: 17alpha-hydroxyprogesterone caproate (17P) administration reportedly improves outcome for women with a previous spontaneous preterm delivery. This study, using in vitro strips of human uterine smooth muscle, aimed to investigate the direct non-genomic effects of 17P on spontaneous and induced contractions in tissues obtained during pregnancy, and in the non-pregnant state. METHODS: Biopsies of human myometrium were obtained at elective cesarean section, and from hysterectomy specimens, and dissected strips suspended for isometric recordings. The effects of 17P (1 nmol/L -10 micro mol/L) on spontaneous and agonist-induced (oxytocin 0.5 nmol/L for pregnant, phenylephrine 10 μmol/L for non-pregnant) contractions were measured. Integrals of contractile activity, including the mean maximal inhibition values (MMI) observed at the maximal concentration, were compared with those from simultaneously run control strips. RESULTS: There was no significant direct effect exerted by 17P on pregnant or non-pregnant human myometrial contractility. The MMI ± SEM for spontaneous contractions in pregnant myometrium was 4.9% ± 7.2 (n = 6; P = 0.309) and for oxytocin-induced contractions was 2.2% ± 1.3 (n = 6; P = 0.128). For non-pregnant myometrium, the MMI ± SEM for spontaneous contractions was 8.8% ± 11.0 (n = 6; P = 0.121) and for phenylephrine induced contractions was -7.9% ± 6.5 (n = 6; P = 0.966). CONCLUSIONS: The putative benefits of 17P for preterm labor prevention are not achieved, even partially, by a direct utero-relaxant effect. These findings outline the possibility that genomic effects of 17P, achieved over long periods of administration, are required for its reported therapeutic benefits

Mapping the Galactic Halo. V. Sgr dSph Tidal Debris 60 degrees from the Main Body

As part of the Spaghetti Project Survey (SPS) we have detected a concentration of giant stars well above expectations for a smooth halo model. The position (l~350, b~50) and distance (~50 kpc) of this concentration match those of the Northern over-density detected by SDSS (Yanny et al. 2000, Ivezic et al. 2000). We find additional evidence for structure at ~80 kpc in the same direction. We present radial velocities for many of these stars, including the first published results from the 6.5m Magellan telescope. The radial velocities for stars in these structures are in excellent agreement with models of the dynamical evolution of the Sgr dwarf tidal debris, whose center is 60 degrees away. The metallicity of stars in these streams is lower than that of the main body of the Sgr dwarf, which may indicate a radial metallicity gradient prior to disruption.Comment: 10 pages, 3 figures accepted in Astrophysical Journal Letter

SLIP4EX- a program for routine slope stability analysis to include the effects of vegetation, reinforcement and hydrological changes

SLIP4EX is a straightforward computer program developed in connection with the EU funded ECOSLOPES project for routine stability analysis and the assessment of the contribution of vegetation to slope stability. The slope section is drawn up and dimensions and parameters are fed in to the Microsoft Excel based program for stability calculations and comparisons of Factors of Safety using different methods of analysis (Bishop, Janbu, Fellenius, Simple, Greenwood). The background and assumptions involved in the derivation of each of the methods is briefly described. The simplicity of the program enables the user to understand the nature of the analysis, explore the parameter assumptions made and compare the different methods of analysis. Soil reinforcement by geosynthetic layers or anchors, and vegetation effects of enhanced cohesion, changed water pressures, mass of vegetation, wind forces and root reinforcement forces are readily included in the analysis. The program is freely available on request from the author