Interior Noise

The generation and control of flight vehicle interior noise is discussed. Emphasis is placed on the mechanisms of transmission through airborne and structure-borne paths and the control of cabin noise by path modification. Techniques for identifying the relative contributions of the various source-path combinations are also discussed along with methods for the prediction of aircraft interior noise such as those based on the general modal theory and statistical energy analysis

Acoustic fatigue: Overview of activities at NASA Langley

A number of aircraft and spacecraft configurations are being considered for future development. These include high-speed turboprop aircraft, advanced vertical take-off and landing fighter aircraft, and aerospace planes for hypersonic intercontinental cruise or flight to orbit and return. Review of the acoustic environment expected for these vehicles indicates levels high enough that acoustic fatigue must be considered. Unfortunately, the sonic fatique design technology used for current aircraft may not be adequate for these future vehicles. This has resulted in renewed emphasis on acoustic fatigue research at the NASA Langley Research Center. The overall objective of the Langley program is to develop methods and information for design of aerospace vehicles that will resist acoustic fatigue. The program includes definition of the acoustic loads acting on structures due to exhaust jets of boundary layers, and subsequent determination of the stresses within the structure due to these acoustic loads. Material fatigue associated with the high frequency structural stress reversal patterns resulting from acoustic loadings is considered to be an area requiring study, but no activity is currently underway

The Effect of Beam Loading on Water Impact Loads and Motions

An investigation of the effect of beam loading on impact loads and motions has been conducted in the Langley impact basin. Water impact tests of flat-bottom 5-inch-and 8-inch-beam models having beam-loading coefficients C(sub Delta) from 62.5 to 544 and a 30 deg dead-rise 5-inch-beam model A having beam-loading coefficients from 208 to 530 are described and the results analyzed to show trends of these heavy-beam-loading data with initial flight-path angle, trim angle, dead-rise angle, and time through- out the impact. Data from flat-bottom model tests, C(sub Delta) = 4.4 to 36.5, and from 30 deg dead-rise model tests, C(sub Delta) = 0.58 and 18.8, are included, along with the heavy-beam-loading data; and variations of these data with beam-loading coefficients are shown. Each of the load and motion coefficients is found to be directly proportional to a power factor of C(sub Delta). For instance, the maximum impact lift coefficient is found C(sub L,max) to be directly proportional to C(sub Delta, exp 0,33) for the flat-bottom model and C(sub Delta, exp 0,45) for the 30 deg dead-rise model. These variations of C(sub L, max) with C(sub Delta) are found to be in agreement with theoretical variations. Finally, an empirical equation for the prediction of C(sub L,max) is presented and is shown to give good agreement with experimental C(sub L, max) for about 500 fixed-trim smooth-water impacts. The range of variables included dead-rise angles from 0 deg to deg, beam-loading coefficients from o.48 to 544, trim angles from 3 deg to deg, and initial flight-path angles from about 2 deg to about deg

The Effect of Beam Loading on Water Impact Loads and Motions

An investigation of the effect of beam loading on impact loads and motions has been conducted in the Langley impact basin. Water impact tests of flat-bottom 5-inch- and 8-inch-beam models having beam-loading coefficients C(sub Delta) from 62.5 to 544 and a 30 0 dead-rise 5-inch-beam model A having beam-loading coefficients from 208 to 530 are described and the results analyzed to show trends of these heavy-beam-loading data with initial flight-path angle, trim angle, dead-rise angle, and time throughout the impact. Data from flat-bottom model tests, C(sub Delta) = 4.4 to 36.5, and from 300 dead-rise model tests, C(sub Delta)A = 0.58 and 18.8, are included, along with the heavy-beam-loading data; and variations of these data with beam-loading coefficients are shown. Each of the load and motion coefficients is found to be directly proportional to a power factor ofC(sub Delta). For instance, the maximum impact lift coefficient C(sub L,max)is found to be directly proportional to C(sub Delta)(sup 0.33) for the flat-bottom model and C(sub Delta)(sup 0.45) for the 30 deg dead-rise model. These variations of C(sub L,max) C(sub Delta) are found to be in agreement with theoretical variations. Finally, an empirical equation for the prediction of C(sub L,max) is presented and is shown to give good agreement with experimental C(sub L,max) for about 500 fixed-trim smooth-water impacts. The range of variables included dead-rise angles from 0 deg to 30 deg, beam-loading coefficients from 0.48 to 544, trim angles from 3 deg to 45 deg and initial flight-path angles from about 2 deg to about 27 deg

South American Plasmodium falciparum after the Malaria Eradication Era: Clonal Population Expansion and Survival of the Fittest Hybrids

Malaria has reemerged in many regions where once it was nearly eliminated. Yet the source of these parasites, the process of repopulation, their population structure, and dynamics are ill defined. Peru was one of malaria eradication's successes, where Plasmodium falciparum was nearly eliminated for two decades. It reemerged in the 1990s. In the new era of malaria elimination, Peruvian P. falciparum is a model of malaria reinvasion. We investigated its population structure and drug resistance profiles. We hypothesized that only populations adapted to local ecological niches could expand and repopulate and originated as vestigial populations or recent introductions. We investigated the genetic structure (using microsatellites) and drug resistant genotypes of 220 parasites collected from patients immediately after peak epidemic expansion (1999–2000) from seven sites across the country. The majority of parasites could be grouped into five clonal lineages by networks and AMOVA. The distribution of clonal lineages and their drug sensitivity profiles suggested geographic structure. In 2001, artesunate combination therapy was introduced in Peru. We tested 62 parasites collected in 2006–2007 for changes in genetic structure. Clonal lineages had recombined under selection for the fittest parasites. Our findings illustrate that local adaptations in the post-eradication era have contributed to clonal lineage expansion. Within the shifting confluence of drug policy and malaria incidence, populations continue to evolve through genetic outcrossing influenced by antimalarial selection pressure. Understanding the population substructure of P. falciparum has implications for vaccine, drug, and epidemiologic studies, including monitoring malaria during and after the elimination phase

NACA Technical Notes

Note presenting testing of a V-bottom model with a dead-rise angle of 30 degrees and the forward half longitudinally curved upward on a radius of 10 beams in the impact basin as part of a program to study the effects of transverse and longitudinal curvature on impact loads of chine-immersed models. The data are presented and analyzed to determine the extent of bow immersion during the impacts

Detection of Ehrlichia chaffeensis in adult and nymphal Amblyomma americanum (Acari: Ixodidae) ticks from Long Island, New York

The lone star tick, Amblyomma americanum (L.), has increased in abundance in several regions of the northeastern United States, including areas of Long Island, NY. Adult and nymphal stage A. americanum collected from several sites on Long Island were evaluated for infection with Ehrlichia chaffeensis, the causative agent of human monocytic ehrlichiosis (HME), by using a nested polymerase chain reaction assay. Fifty-nine (12.5%) of 473 adults and eight of 113 pools of five nymphs each (estimated minimum prevalence of infection 1.4%) contained DNA of E. chaffeensis. These data, coupled with the documented expansion of lone star tick populations in the northeastern United States, confirm that E. chaffeensis is endemic to many areas of Long Island and that HME should be considered among the differential diagnoses of the many distinct tick-borne diseases that occur in this region