Corporate provision of public goods

Milton Friedman famously suggested that firms ought not divert profits toward public goods because shareholders can better make these contributions themselves. Despite this, activist shareholders are increasingly successful in persuading firms to be “socially responsible.” We study firm behavior when shareholders care about public goods as well as profits and when managerial contracts reflect these concerns. Under these ideal conditions, managers redirect more profits toward public goods than shareholders would when acting separately—shareholders are poorer but happier. Further, so long as the public good is sufficiently desirable, the manager selects the socially optimal level of output, despite the mismatch between shareholder preferences and those of society at large

JAPPL-2017-01144_Data

Included is the data that went in to each of our models described in the manuscript. Included in data are: counts of bobwhite, aggregated densities of conservation fields without specific spatial information (i.e., no x y coordinates), and distance sampling metrics needed to run the model

Up-regulation of GPR109A in the substantia nigra of PD patients.

<p>Up-regulation of GPR109A in the substantia nigra of PD patients.</p

A, Reduced Niacin index (NAD/NADP ratio) in RBCs and B, Total plasma metabolites by HPLC/MS.

<p>A. NAD/NADP ratio was significantly reduced in the PD patients compared to age-matched controls (n = 18, p = 0.038). B. Total niacin metabolites from PD patient’s samples were significantly lower than that of their age-matched controls (p = 0.025). This data is in unison with our niacin factor (NAD/NDAP ratio) data.</p

Subject characteristics.

<p>Values represent good to excellent coefficient of correlations (<i>p</i><0.05 for all). Empty cells indicate moderate or low correlations (<i>p</i>>0.05).</p><p>Abbreviations are the same as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone-0109818-t001" target="_blank">Table 1</a>.</p><p>*Sleep4 (PD Sleep questionnaire item 4), restlessness of legs or arms at night or in the evening causing disruption of sleep <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Chaudhuri1" target="_blank">[69]</a>.</p>§<p>PDQ1 (PD Quality of Life questionnaire item 1), difficulty getting around in public.</p>§<p>PDQ3, feeling depressed.</p>§<p>PDQ7, painful muscle cramps or spasms.</p><p>Times woken, number of times woken during EEG night-sleep assessment.</p><p>Actual sleep, sum of EEG light sleep, deep sleep and REM sleep durations.</p><p>Carbidopa, prescribed with dopamine (as Sinemet) to minimize breakdown of levodopa before it crosses the blood brain barrier.</p><p>*High scores indicate less problems.</p>§<p>High scores indicate more problems.</p><p>Subject characteristics.</p

GPR109A expression, NAD/NADH ratio and BHB levels in blood.

<p>(A) Representative GPR109A western blots (B) GPR109A densitometry, (C) NAD/NADH ratio and (D) BHB levels. GPR109A expression and NAD/NADH ratio were tested in the WBCs. The BHB levels were tested in the sera. Young, n = 6; Older, n = 23, PD, n = 22. *<i>p</i> = 0.009 between Age-matched control and PD groups. **<i>p</i> = 0.033 between Age-matched control and PD groups.^§<i>p</i> = 0.071 between Age-matched control and PD groups.</p

Co-localization of GPR109A and microglia in PD and control brain.

<p>Confocal microscopy image of SN of human brain samples showing the glial marker, CD11b (green) co-localized with GPR109A (red). Control sample shows less microglia and GPR109A + cells. Note that all the GPR109+ cells are not co-localized with CD11b maker in control sample. Few neuronal Nuclei (blue) are seen.</p

Illustration of the EEG sleep monitor.

<p>Illustration of the EEG sleep monitor.</p

PD characteristics.

<p>UPDRS total, sum of section 3 of the Unified PD Rating Scale <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-XX1" target="_blank">[62]</a>.</p><p>UPDRS brady, sum of UPDRS section 3 last five items assessing body bradykinesia <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Stebbins1" target="_blank">[26]</a>.</p><p>H&Y, Hoehn & Yahr disease rating scale <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Goetz1" target="_blank">[63]</a>.</p><p>MMSE, mini-mental status examination <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Folstein1" target="_blank">[64]</a>.</p><p>PDQ total, sum of PD Quality of Life questionnaire <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Jenkinson1" target="_blank">[65]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Jenkinson2" target="_blank">[66]</a>.</p><p>RAPID1 (Rapid Assessment of Postural Instability in PD item 1), difficulty in performing activities of daily living (0 = no difficulty; 1 = difficulty) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Chong1" target="_blank">[67]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109818#pone.0109818-Chong2" target="_blank">[68]</a>.</p><p>RAPID2, fear of falling (ranging from 1 = “no fear” to 10 “very fearful”).</p><p>RAPID3, number of falls over the last three months (including near falls).</p><p>Symptoms rating, self-reported rating of PD symptoms, ranging from 1 to 10: 1 = “very bad day” - symptoms are the worse compared to a typical day; 10 = “very good day” - symptoms are absent or minimal compared to a typical day).</p><p>PD characteristics.</p

Associations among PD NAD/NADH ratio, GPR109A, BHB and sleep quality.

<p>Values represent good to excellent coefficient of correlations (p<0.05 for all). Empty cells indicate moderate or low correlations (p>0.05).</p><p>*Sleep11, painful muscle cramps in arms or legs while sleeping at night.</p><p>*Sleep12, wake up early in the morning with painful posturing of arms or legs.</p><p>*Sleep14, feel tired and sleepy after waking in the morning.</p><p>*High scores indicate less problems.</p><p>Associations among PD NAD/NADH ratio, GPR109A, BHB and sleep quality.</p