21,193 research outputs found

    Mechanisms Affecting Recruitment of Yellow Perch in Lake Michigan

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    Report issued on: August 2001INHS Technical Report prepared for Great Lakes Fishery Trus

    ACTH and polymorphisms at steroidogenic loci as determinants of aldosterone secretion and blood pressure

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    The majority of genes contributing to the heritable component of blood pressure remain unidentified, but there is substantial evidence to suggest that common polymorphisms at loci involved in the biosynthesis of the corticosteroids aldosterone and cortisol are important. This view is supported by data from genome-wide association studies that consistently link the CYP17A1 locus to blood pressure. In this review article, we describe common polymorphisms at three steroidogenic loci (CYP11B2, CYP11B1 and CYP17A1) that alter gene transcription efficiency and levels of key steroids, including aldosterone. However, the mechanism by which this occurs remains unclear. While the renin angiotensin system is rightly regarded as the major driver of aldosterone secretion, there is increasing evidence that the contribution of corticotropin (ACTH) is also significant. In light of this, we propose that the differential response of variant CYP11B2, CYP11B1 and CYP17A1 genes to ACTH is an important determinant of blood pressure, tending to predispose individuals with an unfavourable genotype to hypertension

    USING RIGHTS OF FIRST REFUSAL FOR FARMLAND RETENTION

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    How can rights of first refusal protect prime agricultural land? This paper develops a theory for valuing rights of first refusal based on compensation for foreclosing future demand, information asymmetry, and advance purchase of market share. A procedure is developed for governments to use these rights to prevent conversion.Land Economics/Use,

    Junior Faculty Engagement at iSchools: Personal Experience during the First Several Years

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    This roundtable discussion will explore how junior faculty at iSchools have been able to embed their research, teaching, and service activities within their schools, the larger institutions, and broader communities. The session will also focus on the ways in which junior faculty have received guidance in their roles--from the job search through the first several years in a tenure-track position. Roundtable leaders represent a variety of institutions and experiences--as faculty at the University of Illinois at Urbana-Champaign [WJM], the University of Maryland [SP], the University of North Carolina at Chapel Hill [PME], and the University of Texas at Austin [MW], and with doctoral-level preparation at the University of North Carolina at Chapel Hill [WJM, MW], the University of Toronto [SP], and the University of Washington [PME]. While the annual junior faculty mentoring event at the iConference specifically targets junior faculty as participants, this roundtable session offers a more inclusive environment for the discussion of this topic, specifically engaging doctoral students and senior faculty as well as their junior colleagues

    Disruptive Effects of the Coronavirus – Errors of Commission and of Omission?

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    It is increasingly evident that the coronavirus disease, COVID-19, is more than a health problem; it is and will continue to adversely affect work and workplaces, education, families and social engagements, political and environmental dimensions, and financial indicators. Apart from its health ramifications, the crisis is revealing serious challenges in the global supply chain. Those difficulties are, at least in part, consequences of unwise, short-sighted business decisions made over the course of decades to outsource and downsize

    Our Wicked Problem

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    The Coronavirus is more than a health problem. It is a “wicked” problem disrupting work, education, travel, politics, financial indicators, and more. This label came about in 1973 to help describe a special class of situations that are volatile, uncertain and ambiguous, often difficult to recognize, and difficult or impossible to solve because of incomplete, contradictory, and changing requirements. There is no clear problem definition due to interdependencies so the problem cannot be fully understood until after the solution comes about

    ALMA Observations of Circumstellar Disks in the Upper Scorpius OB Association

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    We present ALMA observations of 106 G-, K-, and M-type stars in the Upper Scorpius OB Association hosting circumstellar disks. With these data, we measure the 0.88 mm continuum and 12^{12}CO JJ = 3-2 line fluxes of disks around low-mass (0.141.660.14-1.66 MM_{\odot}) stars at an age of 5-11 Myr. Of the 75 primordial disks in the sample, 53 are detected in the dust continuum and 26 in CO. Of the 31 disks classified as debris/evolved transitional disks, 5 are detected in the continuum and none in CO. The lack of CO emission in approximately half of the disks with detected continuum emission can be explained if CO is optically thick but has a compact emitting area (40\lesssim 40 au), or if the CO is heavily depleted by a factor of at least 1000\sim1000 relative to interstellar medium abundances and is optically thin. The continuum measurements are used to estimate the dust mass of the disks. We find a correlation between disk dust mass and stellar host mass consistent with a power-law relation of MdustM1.67±0.37M_{\mathrm{dust}}\propto M_*^{1.67\pm0.37}. Disk dust masses in Upper Sco are compared to those measured in the younger Taurus star-forming region to constrain the evolution of disk dust mass. We find that the difference in the mean of log(Mdust/M)\log(M_{\mathrm{dust}}/M_*) between Taurus and Upper Sco is 0.64±0.090.64\pm0.09, such that Mdust/MM_{\mathrm{dust}}/M_* is lower in Upper Sco by a factor of 4.5\sim4.5.Comment: 18 pages of text, 11 Figures, 5 Tables. Published in Ap

    Three great Kansas forage crops-- alfalfa, corn, and kafir-corn

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    Citation: Schottler, Martin William and Haan, Samuel P. Design of a central telephone exchange. Senior thesis, Kansas State Agricultural College, 1907.Morse Department of Special CollectionsIntroduction: In treating this subject we will only consider the feeding value of the fodder of these crops, and will not consider the feeding value of the grain, but will compare the feeding value of each as compared with the cost of production and in this way will show which is the most profitable crop for the stockman to feed, also for the farmer to produce. ALFALFA: - Description: Alfalfa is an upright branching smooth perenial plant, growing from one to three feet high, according to conditions. When in bloom it presents a purple or violet color, the flowers instead of being in a head like clover, are in a long,loose cluster or raceme. These are scattered over the plant. The ripe pods are spirally twisted through two or three complete curves, and each pod contains several seeds. Compared with clover it yields heavier. History:- Alfalfa or Lucerne has been cultivated for ages, it was familiar even with the Egyptians, Medes, and Persians. It is said to have grown spontaneously on the high desert regions of Southern and central Asia. It became known in Greece about the time Xerxes invaded that country or about 450 B. C. and was prominent in Roman agriculture before the Christian era. The Romans valued it very highly as forage for the horses of their armies. It was introduced into Spain and southern France from Italy and was carried to Mexico during the Spanish invasion. It was brought from Chili to California in 1854, it soon spread eastward and is now in nearly all of the western states. It is said to have been introduced into New York in 1820 but did not seem to have been valued very highly. Varieties: Besides the common variety, Medicago Saliva, that we are acquainted with here in Kansas. There are two other varieties, they are the
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