1,066 research outputs found

    Experiences with the Greenstone digital library software for international development

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    Greenstone is a versatile open source multilingual digital library environment, emerging from research on text compression within the New Zealand Digital Library Research Project in the Department of Computer Science at the University of Waikato. In 1997 we began to work with Human Info NGO to help them produce fully-searchable CD-ROM collections of humanitarian information. The software has since evolved to support a variety of application contexts. Rather than being simply a delivery mechanism, we have emphasised the empowerment of users to create and distribute their own digital collections

    Binary Frontal Polymerization: Velocity Dependence on Initial Composition

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    Frontal polymerization is a mode of polymerization in which a localized zone of reaction propagates through the coupling of thermal diffusion and the Arrhenius dependence of the reaction rate. The dependence of the front propagation velocity on the initial composition has been determined in initially miscible binary systems of a free-radically cured diacrylate and an amine- or cationically cured epoxy resin. A minimum of the velocity as a function of the monomer mole fraction is observed if the two polymerizations occur independently. Excellent agreement with an analytical description was found with the diacrylate and an amine-cured epoxy but not for a diacrylate and a cationically cured one because of the effect of HCl impurities on the peroxide

    Compressional and EM Wave Velocity Anisotropy in a Temperate Glacier Due to Basal Crevasses, and Implications for Water Content Estimation

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    We have conducted a series of experiments designed to investigate elastic and electromagnetic (EM) velocity anisotropy associated with a preferentially aligned fracture system on a temperate valley glacier in south-central Alaska, USA. Measurements include a three-dimensional compressional wave (P-wave) seismic reflection survey conducted over a 300m × 300m survey patch, with uniform source grid and static checkerboard receiver pattern. Additionally, we acquired a multi-azimuth, multi-offset, polarimetric ground-penetrating radar (GPR) reflection experiment in a wagon-wheel geometry with 94° of azimuthal coverage. Results show azimuthal variation in the P-wave normal-moveout velocity of \u3e3% (3765 and 3630ms-1 in the fast and slow directions respectively) and difference of nearly 5% between the fast (0.164mns-1) and slow (0.156mns-1) EM velocities. Fracture orientations estimated from the GPR and seismic velocity data are consistent and indicate a preferred fracture orientation that is 30–45° oblique to glacier flow; these measurements agree with borehole observations. Anisotropic analysis of the polarimetric data gives a single volumetric water content estimate of 0.73 ± 0.11%. We conclude that meaningful estimates of physical properties in glaciers based on EM or seismic velocity measurements require collecting data such that the presence of anisotropy can be evaluated and an anisotropic analysis employed when necessary

    Continuous profiles of electromagnetic wave velocity and water content in glaciers: an example from Bench Glacier, Alaska, USA

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    We conducted two-dimensional continuous multi-offset georadar surveys on Bench Glacier, south-central Alaska, USA, to measure the distribution of englacial water. We acquired data with a multi channel 25 MHz radar system using transmitter-receiver offsets ranging from 5 to 150 m. We towed the radar system at 5-10 kmh-1 with a snow machine with transmitter/receiver positions established by geodetic-grade kinematic deferentially corrected GPS (nominal 0.5 m trace spacing). For radar velocity analyses, we employed reflection tomography in the pre-stack depth-migrated domain to attain an estimated 2% velocity uncertainty when averaged over three to five wavelengths. We estimated water content from the velocity structure using the complex refractive index method equation and use a three-phase model (ice, water, air) that accounts for compression of air bubbles as a function of depth. Our analysis produced laterally continuous profiles of glacier water content over several kilometers. These profiles show a laterally variable, stratified velocity structure with a low-water-content (about 0-0.5%) shallow layer (about 20-30 m) underlain by high-water-content (1-2.5%) ice

    Conducting LaAlO\u3csub\u3e3\u3c/sub\u3e/SrTiO\u3csub\u3e3\u3c/sub\u3e Heterointerfaces on Atomically-Flat Substrates Prepared by Deionized-Water

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    We have investigated how the recently-developed water-leaching method for atomically-flat SrTiO3 (STO) substrates affects the transport properties of LaAlO3 (LAO) and STO heterointerfaces. Using pulsed laser deposition at identical growth conditions, we have synthesized epitaxial LAO thin-films on two different STO substrates, which are prepared by water-leaching and buffered hydrofluoric acid (BHF) etching methods. The structural, transport, and optical properties of LAO/STO heterostructures grown on water-leached substrates show the same high-quality as the samples grown on BHF-etched substrates. These results indicate that the water-leaching method can be used to grow complex oxide heterostructures with atomically well-defined heterointerfaces without safety concerns

    A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing.

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    Background. Next-generation sequencing of cancers has identified important therapeutic targets and biomarkers. The goal of this pilot study was to compare the genetic changes in a human papillomavirus- (HPV-)positive and an HPV-negative head and neck tumor. Methods. DNA was extracted from the blood and primary tumor of a patient with an HPV-positive tonsillar cancer and those of a patient with an HPV-negative oral tongue tumor. Exome enrichment was performed using the Agilent SureSelect All Exon Kit, followed by sequencing on the ABI SOLiD platform. Results. Exome sequencing revealed slightly more mutations in the HPV-negative tumor (73) in contrast to the HPV-positive tumor (58). Multiple mutations were noted in zinc finger genes (ZNF3, 10, 229, 470, 543, 616, 664, 638, 716, and 799) and mucin genes (MUC4, 6, 12, and 16). Mutations were noted in MUC12 in both tumors. Conclusions. HPV-positive HNSCC is distinct from HPV-negative disease in terms of evidence of viral infection, p16 status, and frequency of mutations. Next-generation sequencing has the potential to identify novel therapeutic targets and biomarkers in HNSCC

    Comparison of electromagnetic and gravitational radiation: What we can learn about each from the other

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    We compare the nature of electromagnetic fields and gravitational fields in linearized general relativity. We carry out this comparison both mathematically and visually. In particular, the “lines of force” visualizations of electromagnetism are contrasted with the recently introduced tendex/vortex eigenline technique for visualizing gravitational fields. Specific solutions, visualizations, and comparisons are given for an oscillating point quadrupole source. Among the similarities illustrated are the quasistatic nature of the near fields, the transverse 1/r nature of the far fields, and the interesting intermediate field structures connecting these two limiting forms. Among the differences illustrated are the meaning of field line motion and of the flow of energy

    Anti-Lu14: A Lutheran Antibody Defining the Product of an Allele at the Lu8 Blood Group Locus 1

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    A ‘new’ Lutheran-related antibody, named anti-Lu14, reacts with approximately 2.4% of random bloods. Red cells of the rare Lu:-8 phenotype are Lu:14. The data indicate, with a high probability, that the Lu 14 antigen is a product of an allele of Lu 8 and that Lu 14 and Lu 8 comprise a third pair of alleles at the Lutheran locus. Red cells of the original Sw (a+) propositus are Lu:14. By coincidence, he has inherited two low-incidence genes. This observation may explain the discrepancy in different families concerning a possible relationship between Sw a and Lutheran. Pedigree information now suggests that Sw a is not a Lutheran gene.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75055/1/j.1423-0410.1977.tb00632.x.pd
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