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Kinosternon herrerai
Number of Pages: 2Integrative BiologyGeological Science
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Kinosternon integrum
Number of Pages: 6Integrative BiologyGeological Science
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Kinosternon leucostomum
Number of Pages: 8Integrative BiologyGeological Science
The effect of Holstein-Friesian genotype and feeding system on selected performance parameters of dairy cows on grass-based systems of milk production in Ireland
End of project reportThe overall objective of this project was to assess, the effect of strain of Holstein-Friesian dairy cow, pasture-based feed system (FS) and their interaction on animal performance in terms of milk productivity and lactation profile, body weight (BW), body condition score (BCS), feed intake and energy balance (EB), reproductive performance and overall economic profitability
Direct Observation of Node-to-Node Communication in Zeolitic Imidazolate Frameworks
Zeolitic imidazolate frameworks (ZIFs) with open-shell transition metal nodes represent a promising class of highly ordered light harvesting antennas for photoenergy applications. However, their charge transport properties within the framework, the key criterion to achieve efficient photoenergy conversion, are not yet explored. Herein, we report the first direct evidence of a charge transport pathway through node-to-node communication in both ground state and excited state ZIFs using the combination of paramagnetic susceptibility measurements and time-resolved optical and X-ray absorption spectroscopy. These findings provide unprecedented new insights into the photoactivity and charge transport nature of ZIF frameworks, paving the way for their novel application as light harvesting arrays in diverse photoenergy conversion devices
Internal Frame Dragging and a Global Analog of the Aharonov-Bohm Effect
It is shown that the breakdown of a {\it global} symmetry group to a discrete
subgroup can lead to analogues of the Aharonov-Bohm effect. At sufficiently low
momentum, the cross-section for scattering of a particle with nontrivial
charge off a global vortex is almost equal to (but definitely different from)
maximal Aharonov-Bohm scattering; the effect goes away at large momentum. The
scattering of a spin-1/2 particle off a magnetic vortex provides an amusing
experimentally realizable example.Comment: (14 pp
MICROGRID MODELING ASSESSMENT FOR CLIMATE TRENDS AND WEATHER EVENTS
This report performs a gap analysis on microgrid models with respect to climate change risks at Naval installations. Six climate change risks are identified for the model analysis including drought, flooding, heat, cold, wildfires, and weather extremes. Each climate change risk is decomposed into ordered effects that inform the impacts that the climate risks may have on microgrids. The climate change risks, ordered effects, and the impacts on microgrids are used to analyze three microgrid models to determine if they adequately incorporate the six climate risks. A model analysis framework is developed to identify gaps in the approach of the models, the input parameters of the models, and the assumptions made in the models. The analysis demonstrates that gaps exist in each model when considering the climate change risks, the ordered effects, and the impacts to the microgrid. These gaps exist in all three models analyzed using the model analysis framework. The identified gaps are used to develop recommendations for ways to improve the incorporation of the climate change risks into microgrid models and the necessary research required to inform that data used in microgrid models.Naval Facilities Engineering CommandCivilian, Department of the NavyCivilian, Department of the NavyCivilian, Department of the NavyCivilian, Department of the NavyApproved for public release. Distribution is unlimited
Notes
Notes by Richard A. Molique, F. Louis Fautsch, John A. Berry, Joseph A. McCabe, Stephen P. Banas, Robert Devine, John J. Locher, and J. S. Montedonico
Concordance rate between copy number variants detected using either high- or medium-density single nucleotide polymorphism genotype panels and the potential of imputing copy number variants from flanking high density single nucleotide polymorphism haplotypes in cattle
peer-reviewedBackground
The trading of individual animal genotype information often involves only the exchange of the called genotypes and not necessarily the additional information required to effectively call structural variants. The main aim here was to determine if it is possible to impute copy number variants (CNVs) using the flanking single nucleotide polymorphism (SNP) haplotype structure in cattle. While this objective was achieved using high-density genotype panels (i.e., 713,162 SNPs), a secondary objective investigated the concordance of CNVs called with this high-density genotype panel compared to CNVs called from a medium-density panel (i.e., 45,677 SNPs in the present study). This is the first study to compare CNVs called from high-density and medium-density SNP genotypes from the same animals. High (and medium-density) genotypes were available on 991 Holstein-Friesian, 1015 Charolais, and 1394 Limousin bulls. The concordance between CNVs called from the medium-density and high-density genotypes were calculated separately for each animal. A subset of CNVs which were called from the high-density genotypes was selected for imputation. Imputation was carried out separately for each breed using a set of high-density SNPs flanking the midpoint of each CNV. A CNV was deemed to be imputed correctly when the called copy number matched the imputed copy number.
Results
For 97.0% of CNVs called from the high-density genotypes, the corresponding genomic position on the medium-density of the animal did not contain a called CNV. The average accuracy of imputation for CNV deletions was 0.281, with a standard deviation of 0.286. The average accuracy of imputation of the CNV normal state, i.e. the absence of a CNV, was 0.982 with a standard deviation of 0.022. Two CNV duplications were imputed in the Charolais, a single CNV duplication in the Limousins, and a single CNV duplication in the Holstein-Friesians; in all cases the CNV duplications were incorrectly imputed.
Conclusion
The vast majority of CNVs called from the high-density genotypes were not detected using the medium-density genotypes. Furthermore, CNVs cannot be accurately predicted from flanking SNP haplotypes, at least based on the imputation algorithms routinely used in cattle, and using the SNPs currently available on the high-density genotype panel
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