Individual changes in carboxyhaemoglobin.

<p>Each line corresponds to one subject. Individual mean value was calculated when more than one blood sample was collected per week. The bar graphs represent the mean values of the 19 subjects. The grey bars represent the 4 weeks of rHuEpo administration.</p

Resting blood pressure and heart rate before, during and 4 weeks post rHuEpo administration.

<p><i>N</i> = 19. Values are means (SD). No significant differences compared to baseline values were observed.</p

Haematocrit, haemoglobin concentration, reticulocytes, haemoglobin mass, blood volumes, carboxyhaemoglobin and body mass before, during and 4 weeks post rHuEpo administration.

<p><i>N</i> = 19. Values are means (SD). Significant differences compared to baseline values are indicated by *<i>P</i><0.05. Hb_mass: Haemoglobin mass.</p

Individual changes in Hb_mass (A), red cell (B), plasma (C) and blood (D) volume.

<p>Each line corresponds to one subject and each symbol corresponds to the same subject in all figures. Individual mean value was calculated when more than one blood sample was collected per week. The bar graphs represent the mean values of the 19 subjects. The grey bars represent the 4 weeks of rHuEpo administration.</p

Changes in haemoglobin mass, blood, red cell and plasma volume during and for 4 weeks post rHuEpo administration.

<p><i>N</i> = 19. Values are means (95% confidence interval). Significant changes are indicated by *<i>P</i><0.05.</p

Running 3,000 m time trial performance and maximal oxygen uptake.

<p>Group 1 included subjects who had a history of running (n = 9) and group 2 included the other subjects who were involved in other activities (n = 9). Values are means (SD). Significant differences compared to baseline values are indicated by *<i>P</i><0.05. Significant differences compared to the first 1,000 m split time within the same time trial. ^†<i>P</i><0.05. RPE: Borg’s rating of perceived exertion; O_{2 max}: Maximal oxygen uptake.</p