Semi quantitative data

Raw semi-quantitative data and descriptive statistic

Additional file 1: of Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma

Supplementary Tables S1-S4. The analyzed transcriptomic datasets. Table S2. The 197 genes harboring verified somatic mutations in high-risk neuroblastoma. Three official gene symbols (WDR85, MLL5, and C12orf69) are updated. Table S3. Commonly enriched (FDR < 0.01, intersect > 3) KEGG pathways between the MN_hi genes and the genes harboring verified genetic variants. Table S4. DNA-binding extracted from the gene-sets defined by the MSigDB database. (PDF 154 kb

Additional file 2: of Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma

Supplementary Figure S1. Figure S1. RA-induced cell-dedifferentiation markers in HR-NB over-represent the targets of MYC but not somatic mutations. (PDF 333 kb

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Phase reconstruction of an oscillating dielectric disc pendulum, recorded using off-axis holography at 290 GHz. Frames captured at 25 fps = Exp3. !May contain flashing patterns

Supplementary document for Real-time millimeter wave holography with an arrayed detector - 6822102.pdf

Supplementary document for main articl

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Phase reconstruction of an oscillating dielectric disc pendulum, recorded using off-axis holography at 290 GHz. Frames captured at 43 fps = Exp2. !May contain flashing patterns

High-Throughput, Automated Protein A Purification Platform with Multiattribute LC–MS Analysis for Advanced Cell Culture Process Monitoring

The levels of many product related variants observed during the production of monoclonal antibodies are dependent on control of the manufacturing process, especially the cell culture process. However, it is difficult to characterize samples pulled from the bioreactor due to the low levels of product during the early stages of the process and the high levels of interfering reagents. Furthermore, analytical results are often not available for several days, which slows the process development cycle and prevents “real time” adjustments to the manufacturing process. To reduce the delay and enhance our ability to achieve quality targets, we have developed a low-volume, high-throughput, and high-content analytical platform for at-line product quality analysis. This workflow includes an automated, 96-well plate protein A purification step to isolate antibody product from the cell culture fermentation broth, followed by rapid, multiattribute LC–MS analysis. We have demonstrated quantitative correlations between particular process parameters with the levels of glycosylated and glycated species in a series of small scale experiments, but the platform could be used to monitor other attributes and applied across the biopharmaceutical industry

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Phase reconstruction of an oscillating dielectric disc pendulum, recorded using off-axis holography at 290 GHz. Frames captured at 103 fps = Exp0. !May contain flashing patterns

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Phase reconstruction of an oscillating dielectric disc pendulum, recorded using off-axis holography at 290 GHz. Frames captured at 72 fps = Exp1. !May contain flashing patterns

Additional file 1: of Online interventions for problem gamblers with and without co-occurring problem drinking: study protocol of a randomized controlled trial

SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents. (DOC 121 kb