An Introduction to the Special Volume on "Political Methodology"

This special volume of the Journal of Statistical Software on political methodology includes 14 papers, with wide-ranging software contributions of political scientists to their own field, and more generally to statistical data analysis in the the social sciences and beyond. Special emphasis is given to software that is written in or can cooperate with the R system for statistical computing.

Estimating Indigenous Australian employment in the private sector

Impetus for attempting to delineate 'real' private sector employment derived from concerns regarding the shortcomings of data on this issue identified by the review of the Aboriginal Employment Development Policy (AEDP). In seeking to address these concerns, private sector employment is defined here as consisting of activities that do not depend primarily on government funding for their existence. Using census data, two methods are employed to estimate change in the number of Indigenous people employed in this redefined private sector in 1986 and 1991. The first, a residual approach, uses a mix of census statistics and administrative data sets. The second is based on judicious scrutiny of detailed industry tables from the census cross-classified by private sector employment. Revised statistical limits of Indigenous employment in the private sector are produced with intercensal growth substantially deflated. This paper considers the determinants of employment income for Indigenous Australians compared with non-Indigenous Australians. Ordinary Least Square (OLS) regression techniques are applied to 1991 Census data to consider the question: does the lower income of these Indigenous people reflect differences in their factor endowments (like education) rewarded in the labour market, or are they rewarded differently for the same set of endowments than are non-Indigenous Australians. The results show that the main source of lower incomes for Indigenous Australians was their smaller endowment of human capital characteristics. The paper concludes with a discussion of the policy implications of these results

African American Men Survey

A comprehensive survey looking at how African-American men view their lives in the United States and their outlook for the future. The survey gauges the views and experiences of African-American men on marriage and family, education, careers and health, among other issues, and includes comparisons to the views and experiences of African-American women and white men and women. The African-American Men Survey is the 15th survey in a series generated under a three-way partnership between The Washington Post, the Kaiser Family Foundation and Harvard University. The three organizations work together to pick the survey topics, design the survey instruments and analyze the results. The survey's findings were published in the June 4, 2006, edition of The Washington Post. This survey was conducted by telephone from March 20 to April 29, 2006, among 2,864 randomly selected adults nationwide, including: 1,328 black men; 507 black women; 437 white men and 495 white women. Results for total respondents have been weighted so that black respondents are represented in proportion to their actual share of the population. Margin of sampling error is plus or minus 3 percentage points for results based on all respondents or black men, 5 percentage points for black women and 6 percentage points for white men or women. Hispanics and Asians were interviewed along with white and black respondents, but because of the relative size of those populations, there were not enough respondents to break out separately. The complete survey results and detailed methodology description are available in the toplines document

Ornamental plant domestication by aesthetics-driven human cultural niche construction

Unlike plants that were domesticated to secure food, the domestication and breeding of ornamental plants are driven by aesthetic values. Here, we examine the major elements of the extended evolutionary synthesis (EES) theory that bridges the gap between the biology of ornamental plant domestication and the sociocultural motivations behind it. We propose that it involves specific elements of cumulative cultural evolution (CCE), plant gene-human culture coevolution (PGHCC), and niche construction (NC). Moreover, ornamental plant domestication represents an aesthetics-driven dimension of human niche construction that coevolved with socioeconomic changes and the adoption of new scientific technologies. Initially functioning as symbolic and aesthetic assets, ornamental plants became globally marketed material commodities as a result of the co-dependence of human CCE and prestige-competition motivations

An Introduction to the Special Volume on

This special volume of the Journal of Statistical Software on political methodology includes 14 papers, with wide-ranging software contributions of political scientists to their own field, and more generally to statistical data analysis in the the social sciences and beyond. Special emphasis is given to software that is written in or can cooperate with the R system for statistical computing

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation.

ObjectivePostprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury. Our goal was to examine the interactions between postprandial lipoproteins, LPS, and apoE3 and apoE4 on monocyte activation.Methods and resultsWe showed that apoE3 complexed to phospholipid vesicles attenuates LPS-induced THP-1 monocyte cytokine expression, while apoE4 increases expression. ELISA revealed that apoE3 binds to LPS with higher affinity than apoE4. Electron paramagnetic resonance (EPR) spectroscopy of site-directed spin labels placed on specific amino acids of apoE3 showed that LPS interferes with conformational changes normally associated with lipid binding. Specifically, compared to apoE4, apoE bearing the E3-like R112→Ser mutation displays increased self association when exposed to LPS, consistent with a stronger apoE3-LPS interaction. Additionally, lipolysis of fasting VLDL from normal human donors attenuated LPS-induced TNFα secretion from monocytes to a greater extent than postprandial VLDL, an effect partially reversed by blocking apoE. This effect was reproduced using fasting VLDL lipolysis products from e3/e3 donors, but not from e4/e4 subjects, suggesting that apoE3 on fasting VLDL prevents LPS-induced inflammation more readily than apoE4.ConclusionPostprandial apoE isoform and conformational changes associated with VLDL dramatically modulate vascular inflammation