358 research outputs found

    How the Physical Work Environment Can Affect Individual Productivity

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    Master's thesis in Strategic ManagementThe topic of this thesis is about how the physical work environment affects individual productivity, and with focus on productivity through the well-being aspect of individuals. The thesis has a theoretical approach with a pilot-exercise including a pilot experiment and questionnaire. This approach was chosen as the research question is comprehensive, and with the timeframe to complete this thesis. A theoretical approach gives the possibility to further go into the subject, and the pilot-exercise gives insight into how a larger-scale study on this topic could be conducted. Further, the physical work environment contains several elements that can affect an individual’s productivity and well-being, so the physical work environment aspect has been restricted to only looking at one factor, which is the color aspect. The thesis research question is: “How does the physical work environment affect individual productivity?” The hypothesis in the thesis focuses on how color affects individual well-being, and to test for this a pilot-exercise was used, where the objective is to provide learning points that can be used in a full-scale study. There will be used a quantitative approach, where both a pilot experiment and questionnaire is created to collect the data needed, which can contribute with learning points. In total the pilot-exercises had a sample of thirty participants that were divided between two different color environments, the sample was too small to give any results but it will give learning points regarding the methods used. A statistical program, Stata, was used to analyze the results from the pilot-exercise, where the data from the pilot experiment and questionnaire were analyzed by using an independent samples t-test. An analysis was conducted, even though knowing that the sample was too small to give any real conclusion if the hypothesis should be rejected or not. The results from the analyses done on the pilot experiment and questionnaire gave no significant results, which was expected due to the sample size used, but it did provide valuable insight into how a larger-scale study could be conducted. The theoretical approach showed that the physical work environment impacts people both physically and psychologically, and that the individual productivity is affected by the physical work environment both negatively and positively

    Systemic risk of maritime-related oil spills viewed from an Arctic and insurance perspective

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    Post-print (lokagerĂ° höfundar)There is a wish for economic development in the Arctic, especially in relation to the region's untapped marine and hydrocarbon resources. However, such developments are inherently risky, entailing the possibility of trade-offs and potentially jeopardizing a fragile and pristine natural environment which provides multiple sources of well-being to the Arctic's four million inhabitants. When the risks of economic development are evaluated, they are usually assessed on a micro (enterprise risk) and/or meso level (portfolio risk, such as an industry). Systemic risk is considered to a much lesser degree. There is also limited discussion about mitigation methods, including the role of insurance in dealing with the consequences of failures, such as oil spills. The aim of this study is, therefore, to explore the systemic risk of maritime-related oil spills in general and place the findings in an Arctic and insurance perspective. The study is based on secondary data relating to major maritime-related oil spills from drilling and shipping. Two analytical frameworks were employed, one explaining the scaling of risks, and another showing the interplay between subsistence and monetized economies in tandem with their institutional, environmental, social and cultural context. The findings suggest, if the worst-case scenario materializes, that maritime-related oil spills may have social/cultural, environmental, and economic impacts, in addition to security/policy implications, as well as affecting businesses involved in the disaster and their partners. This study has academic implications since there are, so far, limited studies carried out on systemic-level risk, but it also has policy relevance, for instance for local and regional authorities and international bodies, such as the Arctic Council, in terms of holistic risk-assessment and its recommended use of appropriate decision-making and evaluative frameworks such as ecosystem-based management.This paper has been supported by funding from two sources. Lara Johannsdottir received a Fulbright Arctic Initiative Scholarship from the US government. David Cook is supported by the NordForsk-funded Nordic Centre of Excellence project (award 76654), ‘Arctic Climate Predictions: Pathways to Resilient, Sustainable Societies’ (ARCPATH).Peer Reviewe

    A cross-sectional study on nutrient intake and -status in inflammatory bowel disease patients.

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    To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.Inflammatory bowel disease (IBD) can be associated with nutritional problems. The aim of this study was to investigate diet and nutritional status of IBD patients.A total of 78 participants (35 men and 43 women aged 18-74 years) were included in this cross-sectional study. The majority (80 %) of the participant received infliximab treatment. Participants filled out disease related questionnaires and 31 participants also a 3-day food record. Body composition was measured and blood samples analysed in order to estimate nutritional status.The majority (87 %) claimed that diet affects digestive tract symptoms and 72 % had changed diet accordingly. The most common foods restricted were dairy products (60 %), processed meat (55 %), soft drinks (46 %), alcohol (45 %) and fast food (44 %). Body mass index was mostly in the overweight range but 46 % of the participants had been diagnosed with some nutritional deficiency since IBD diagnosis (most common was iron deficiency: 39 %). Patients who restricted meat products had lower ferritin values (48 ± 39 vs. 95 ± 74 Όg/L, P = 0.011). Intake of vitamin D and calcium were not adequate (65 % below recommeded intake for both) and 60 % had poor vitamin D status.IBD patients often change their dietary intake in order to affect digestive tract symptoms. Many patients have a history of nutrient deficiency. Restriction of dairy and meat consumption is common and is negatively associated with intake or status of micronutrients like calcium and iron. Dietary advice by a dietitian and use of potentially helpful dietary supplements is indicated.Science funds of the Landspitali- The National University Hospital of Icelan

    Monitoring Cognitive Workload Using Vocal Tract and Voice Source Features

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    Monitoring cognitive workload from speech signals has received much attention from researchers in the past few years as it has the potential to improve performance and fidelity in human decision making. The bulk of the research has focused on classifying speech from talkers participating in cognitive workload experiments using simple reading tasks, memory span tests and the Stroop test, typically into three levels of low, medium and high cognitive workload. This study focuses on using parameters extracted from the vocal tract and the voice source components of the speech signal for cognitive workload monitoring. The experiment used in this study contains 98 participants, the levels were obtained by using a reading task and three Stroop tasks which were randomly ordered for each participant and an adequate rest time was used inbetween tasks to mitigate the effect of cognitive workload from one task affecting the subsequent one. Vocal tract features were obtained from the first three formants and voice source features were extracted using signal analysis on the inverse filtered speech signal. The results show that on their own, the vocal tract features outperform the voice source features. The MCR of 33.92% ± 1.05 was achieved with a SVM classifier. A weighted combination of vocal tract and voice source features classified with SWM classifier fused at the output level achieved the lowest MCR of  32.5%

    Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer

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    We have studied a set of 40 human lobular breast cancers for loss of heterozygosity (LOH) at various chromosome locations and for mutations in the coding region plus flanking intron sequences of the E-cadherin gene. We found a high frequency of LOH (100%, 31/31) at 16q21–q22.1. A significantly higher level of LOH was detected in ductal breast tumours at chromosome arms 1p, 3p, 9p, 11q, 13q and 18q compared to lobular breast tumours. Furthermore, we found a significant association between LOH at 16 q containing the E-cadherin locus and lobular histological type. Six different somatic mutations were detected in the E-cadherin gene, of which three were insertions, two deletions and one splice site mutation. Mutations were found in combination with LOH of the wild type E-cadherin locus and loss of or reduced E-cadherin expression detected by immunohistochemistry. The mutations described here have not previously been reported. We compared LOH at different chromosome regions with E-cadherin gene mutations and found a significant association between LOH at 13 q and E-cadherin gene mutations. A significant association was also detected between LOH at 13q and LOH at 7q and 11q. Moreover, we found a significant association between LOH at 3 p and high S phase, LOH at 9p and low ER and PgR content, LOH at 17p and aneuploidy. We conclude that LOH at 16q is the most frequent chromosome alteration and E-cadherin is a typical tumour suppressor gene in lobular breast cancer. © 1999 Cancer Research Campaig

    Assessing cognitive workload using cardiovascular measures and voice

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    Monitoring cognitive workload has the potential to improve both the performance and fidelity of human decision making. However, previous efforts towards discriminating further than binary levels (e.g., low/high or neutral/high) in cognitive workload classification have not been successful. This lack of sensitivity in cognitive workload measurements might be due to individual differences as well as inadequate methodology used to analyse the measured signal. In this paper, a method that combines the speech signal with cardiovascular measurements for screen and heartbeat classification is introduced. For validation, speech and cardiovascular signals from 97 university participants and 20 airline pilot participants were collected while cognitive stimuli of varying difficulty level were induced with the Stroop colour/word test. For the trinary classification scheme (low, medium, high cognitive workload) the prominent result using classifiers trained on each participant achieved 15.17 ± 0.79% and 17.38 ± 1.85% average misclassification rates indicating good discrimination at three levels of cognitive workload. Combining cardiovascular and speech measures synchronized to each heartbeat and consolidated with short-term dynamic measures might therefore provide enhanced sensitivity in cognitive workload monitoring. The results show that the influence of individual differences is a limiting factor for a generic classification and highlights the need for research to focus on methods that incorporate individual differences to achieve even better results. This method can potentially be used to measure and monitor workload in real time in operational environments

    Synergies and Trade-Offs in the Sustainable Development Goals—The Implications of the Icelandic Tourism Sector

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    Publisher's version (Ăștgefin grein)The development of major economic sectors can provide the bedrock on which long-lasting national economic prosperity is formed. Iceland's tourism sector is an example of a rapidly expanded industry in recent years, to the extent that it has become the largest sectoral contributor to the nation's economy. The growth of the sector has led to a number of sustainability impacts, thus presenting opportunities and challenges in terms of meeting the 17 Sustainable Development Goals (SDGs) of the United Nations. Using the case study of Iceland, this paper aims to advance the conceptual understanding of the synergies and trade-offs between a nation's tourism sector and performance across the 169 targets of the SDGs. Empirical results were derived from four theme-based focus groups comprised of expert participants, who were tasked with completing scoresheets concerning their perception of the extent of synergies and trade-offs for each target. The majority (126 in number) of the mean scoresheet outcomes for the SDG targets revealed neither synergies nor trade-offs. However, 32 synergies and 11 trade-offs were identified. Many of the target synergies related to new economic opportunities, such as jobs, employment, and training for young people. Target trade-offs tended to be environmental and social. In particular, concern was voiced about the greenhouse gas emissions of the Icelandic tourism sector, which derives from international aviation, cruise ships, and rental car usage. The outcomes of this study are of particular relevance to tourism companies, policy-makers, and governance institutions, all of whom are increasingly endeavouring to link their activities with the fulfilment of the SDGs, maximising synergies, mitigating the extent of any potential trade-offs, and potentially transforming trade-offs into synergies. Furthermore, the results are likely of interest to academics focused on researching the broad sustainability impacts of economic sectors and their contribution to meeting the visionary goals of the SDGs.This research was funded by NordForsk (grant number 76654) via their financial support to the Nordic Centre of Excellence ARCPATH (Arctic Climate Predictions—Pathways to Resilient, Sustainable Communities).Peer Reviewe

    Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

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    AbstractTransgenic FVB/N mice overexpressing human (Hu) or mouse (Mo) Alzheimer amyloid precursor protein (APP695) die early and develop a CNS disorder that includes neophobia and impaired spatial alternation, with diminished glucose utilization and astrogliosis mainly in the cerebrum. Age at onset of neophobia and age at death decrease with increasing levels of brain APP. HuAPP transgenes induce death much earlier than MoAPP transgenes expressed at similar levels. No extracellular amyloid was detected, indicating that some deleterious processes related to APP overexpression are dissociated from formation of amyloid. A similar clinical syndrome occurs spontaneously in ∌20% of nontransgenic mice when they reach mid-to late-adult life, suggesting that APP overexpression may accelerate a naturally occuring age-related CNS disorder in FVB/N mice

    Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome

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    We examined adenomas and cancers from hereditary non-polyposis colorectal cancer (HNPCC) syndrome patients for the presence of frameshift mutations in the smooth-muscle myosin gene, MYH11. Our results show that mutations in MYH11 occur more frequently in cancers than adenomas (P=0.008) and are dependent on microsatellite instability (MSI+)
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