Bibliographische Erschließung der Allgemeinen Literatur-Zeitung als Instrument universitärer Forschung : Weimarer Bibliographie im Jenaer Sonderforschungsbereich

Die Allgemeine Literatur-Zeitung (A.L.Z.) war insbesondere in ihrer Jenaer Periode zwischen 1785 und 1803 (anschließend erschien sie bis 1849 in Halle) das auflagenstärkste und wohl auch verbreitetste wie einflussreichste Rezensionsorgan im deutschsprachigen Raum. Ihr ambitioniertes Ziel war es, die gesamte aktuelle Literaturproduktion aus allen Wissensgebieten kritisch zu begleiten. Der vorliegende Aufsatz ordnet die Erschließung der A.L.Z in den Kontext der Weimarer bibliographischen Projekte ein und stellt die Erfassungsgrundsätze sowie Einzelheiten der Recherchemöglichkeiten dar. Das Projekt begann als eine Gemeinschaftsarbeit der Herzogin Anna Amalia Bibliothek Weimar und des Sonderforschungsbereichs 482 „Ereignis Weimar-Jena. Kultur um 1800“

Regenerative potential of human adipose-derived stromal cells of various origins

AbstractIn regenerative concepts, the potential of adult stem cells holds great promise concerning an individualized therapeutic approach. These cells provide renewable progenitor cells to replace aged tissue, and play a significant role in tissue repair and regeneration.In this investigation, the characteristics of different types of adipose tissue are analysed systematically with special attention to their proliferation and differentiation potential concerning the angiogenic and osteogenic lineage. Tissue samples from subcutaneous, visceral, and omental fat were processed according to standard procedures. The cells were characterized and cultivated under suitable conditions for osteogenic and angiogenic cell culture. The development of the different cell cultures as well as their differentiation were analysed morphologically and immunohistochemically from cell passages P1 to P12. Harvesting and isolation of multipotent cells from all three tissue types could be performed reproducibly. The cultivation of these cells under osteogenic conditions led to a morphological and immunohistochemical differentiation; mineralization could be detected. The most stable results were observed for the cells of subcutaneous origin. An osteogenic differentiation from adipose-derived cells from all analysed fatty tissues can be achieved easily and reproducibly. In therapeutic concepts including angiogenic regeneration, adipose-derived cells from subcutaneous tissue provide the optimal cellular base

Detecting Bias in Monte Carlo Renderers using Welch’s t-test

When checking the implementation of a new renderer, one usually compares the output to that of a reference implementation. However, such tests require a large number of samples to be reliable, and sometimes they are unable to reveal very subtle differences that are caused by bias, but overshadowed by random noise. We propose using Welch’s t-test, a statistical test that reliably finds small bias even at low sample counts. Welch’s t-test is an established method in statistics to determine if two sample sets have the same underlying mean, based on sample statistics. We adapt it to test whether two renderers converge to the same image, i.e., the same mean per pixel or pixel region. We also present two strategies for visualizing and analyzing the test’s results, assisting us in localizing especially problematic image regions and detecting biased implementations with high confidence at low sample counts both for the reference and tested implementation