Tapping to a slow tempo in the presence of simple and complex musical meters reveals experience-specific biases for processing music

Musical meters vary considerably across cultures, yet relatively little is known about how culture-specific experience influences metrical processing. In Experiment 1, we compared American and Indian listeners\u27 synchronous tapping to slow sequences. Inter-tone intervals contained silence or to-be-ignored rhythms that were designed to induce a simple meter (familiar to Americans and Indians) or a complex meter (familiar only to Indians). A subset of trials contained an abrupt switch from one rhythm to another to assess the disruptive effects of contradicting the initially implied meter. In the unfilled condition, both groups tapped earlier than the target and showed large tap-tone asynchronies (measured in relative phase). When inter-tone intervals were filled with simple-meter rhythms, American listeners tapped later than targets, but their asynchronies were smaller and declined more rapidly. Likewise, asynchronies rose sharply following a switch away from simple-meter but not from complex-meter rhythm. By contrast, Indian listeners performed similarly across all rhythm types, with asynchronies rapidly declining over the course of complex- and simple-meter trials. For these listeners, a switch from either simple or complex meter increased asynchronies. Experiment 2 tested American listeners but doubled the duration of the synchronization phase prior to (and after) the switch. Here, compared with simple meters, complex-meter rhythms elicited larger asynchronies that declined at a slower rate, however, asynchronies increased after the switch for all conditions. Our results provide evidence that ease of meter processing depends to a great extent on the amount of experience with specific meters

A survey of the properties of early-type galaxies

A compilation of the properties of elliptical and early disk galaxies was completed. In addition to material from the literature, such as Infrared Astronomy Satellite (IRAS) fluxes, the compilation includes recent measurements of HI and CO, as well as a review of the x ray properties by Forman and Jones. The data are used to evaluate the gas content of early systems and to search for correlations with x ray emission. The interstellar medium in early-type galaxies is generally dominated by hot interstellar gas (T approx. 10 to the 7th power K; c.f. the review by Fabbiano 1989 and references therein). In addition, a significant fraction of these galaxies show infrared emission (Knapp, et al., 1989), optical emission lines, and visible dust. Sensitive studies in HI and CO of a number of these galaxies have been completed recently, resulting in several detections, particularly of the later types. Researchers wish to understand the connection among these different forms of the interstellar medium, and to examine the theoretical picture of the fate of the hot gas. To do so, they compiled observations of several forms of interstellar matter for a well-defined sample of early-type galaxies. Here they present a statistical analysis of this data base and discuss the implications of the results

Spin Polarization and Transport of Surface States in the Topological Insulators Bi2Se3 and Bi2Te3 from First Principles

We investigate the band dispersion and the spin texture of topologically protected surface states in the bulk topological insulators Bi2Se3 and Bi2Te3 by first-principles methods. Strong spin-orbit entanglement in these materials reduces the spin-polarization of the surface states to ~50% in both cases; this reduction is absent in simple models but of important implications to essentially any spintronic application. We propose a way of controlling the magnitude of spin polarization associated with a charge current in thin films of topological insulators by means of an external electric field. The proposed dual-gate device configuration provides new possibilities for electrical control of spin.Comment: 4+ pages, 3 figure

Bound states and E_8 symmetry effects in perturbed quantum Ising chains

In a recent experiment on CoNb_2O_6, Coldea et al. [Science 327, 177 (2010)] found for the first time experimental evidence of the exceptional Lie algebra E_8. The emergence of this symmetry was theoretically predicted long ago for the transverse quantum Ising chain in the presence of a weak longitudinal field. We consider an accurate microscopic model of CoNb_2O_6 incorporating additional couplings and calculate numerically the dynamical structure function using a recently developed matrix-product-state method. The excitation spectra show bound states characteristic of the weakly broken E_8 symmetry. We compare the observed bound state signatures in this model to those found in the transverse Ising chain in a longitudinal field and to experimental data.Comment: 4 pages, 3 figure

A Gravity Dual and LHC Study of Single-Sector Supersymmetry Breaking

We propose a gravitational dual of ``single-sector'' models of supersymmetry breaking which contain no messenger sector and naturally explain the scale of supersymmetry breaking and the fermion mass hierarchy. In five dimensions these models can be given a simple interpretation. Inspired by flux-background solutions of type IIB supergravity, a metric background that deviates from AdS_5 in the IR breaks supersymmetry, while the fermion mass hierarchy results from the wavefunction overlap of bulk fermions with a UV-confined Higgs field. The first and second generation squarks and sleptons, which are localized near the IR brane, directly feel the supersymmetry breaking and obtain masses of order 10 TeV. These are interpreted as composite states of the dual 4D theory. The gauginos and third generation squarks and sleptons are elementary states that obtain soft masses of order 1 TeV at the loop level via direct gauge mediation. This particle spectrum leads to distinctive signatures at the LHC, similar to the usual gauge mediation with a neutralino NLSP that decays promptly to a gravitino LSP, but with lower event rates. Nevertheless we show that with 1-10 fb^{-1} of LHC data "single-sector" models can easily be detected above background and distinguished from conventional gravity and gauge mediation.Comment: 35 pages, 6 figures, LaTe

RNA-Seq optimization with eQTL gold standards.

BackgroundRNA-Sequencing (RNA-Seq) experiments have been optimized for library preparation, mapping, and gene expression estimation. These methods, however, have revealed weaknesses in the next stages of analysis of differential expression, with results sensitive to systematic sample stratification or, in more extreme cases, to outliers. Further, a method to assess normalization and adjustment measures imposed on the data is lacking.ResultsTo address these issues, we utilize previously published eQTLs as a novel gold standard at the center of a framework that integrates DNA genotypes and RNA-Seq data to optimize analysis and aid in the understanding of genetic variation and gene expression. After detecting sample contamination and sequencing outliers in RNA-Seq data, a set of previously published brain eQTLs was used to determine if sample outlier removal was appropriate. Improved replication of known eQTLs supported removal of these samples in downstream analyses. eQTL replication was further employed to assess normalization methods, covariate inclusion, and gene annotation. This method was validated in an independent RNA-Seq blood data set from the GTEx project and a tissue-appropriate set of eQTLs. eQTL replication in both data sets highlights the necessity of accounting for unknown covariates in RNA-Seq data analysis.ConclusionAs each RNA-Seq experiment is unique with its own experiment-specific limitations, we offer an easily-implementable method that uses the replication of known eQTLs to guide each step in one's data analysis pipeline. In the two data sets presented herein, we highlight not only the necessity of careful outlier detection but also the need to account for unknown covariates in RNA-Seq experiments