6 research outputs found
ââWhatâ â and ââWhereâ â in Word Reading: Ventral Coding of Written Words Revealed by Parietal Atrophy Abstract
& The visual system of literate adults develops a remarkable perceptual expertise for printed words. To delineate the aspects of this competence intrinsic to the occipitotemporal ââwhatâ â pathway, we studied a patient with bilateral lesions of the occipitoparietal ââwhereâ â pathway. Depending on critical geometric features of the display (rotation angle, letter spacing, mirror reversal, etc.), she switched from a good performance, when her intact ventral pathway was sufficient to encode words, to severely impaired reading, when her parietal lesions prevented the use of alternative reading strategies as a result of spatial and attentional impairments. In particular, reading was disrupted (a) by rotating word by more than 508, providing an approximation of the invariance range for words encodin
Proteomic response of Macrobrachium rosenbergii hepatopancreas exposed to chlordecone: Identification of endocrine disruption biomarkers?
The present work is the first study investigating the impacts
of chlordecone, an organochlorine insecticide, on the proteome of the
decapod crustacean Macrobrachium rosenbergii, by gel-free proteomic
analysis of the hepatopancreas protein expression variations in organisms
exposed to three environmental relevant concentrations of chlordecone
(i.e. 0.2, 2 and 20 ÎŒg/L). Results revealed that 62 proteins were
significantly up- or down-regulated in exposed prawns compared to
controls. Most of these proteins are involved in important physiological
processes such as ion transport, defense mechanisms and immune system,
cytoskeleton dynamics, or protein synthesis and degradation. Moreover, it
appears that 6% of the deregulated protein are involved in the endocrine
system and in the hormonal control of reproduction or development
processes of M. rosenbergii (e.g. vitellogenin, farnesoic acid omethyltransferase).
These results indicate that chlordecone is
potentially an endocrine disruptor compound for decapods, as already
observed in vertebrates. These protein modifications could lead to
disruptions of growth and reproduction of M. rosenbergii, and therefore
of the fitness population on the long-term. Besides, these disrupted
proteins could be suggested as biomarkers of exposure for endocrine
disruptions in invertebrates. However, further investigations are needed
to complete understanding of action mechanisms of chlordecone on proteome
and endocrine system of crustaceans
âWhatâ and âWhereâ in Word Reading: Ventral Coding of Written Words Revealed by Parietal Atrophy
Bioaccumulation, distribution and elimination of chlordecone in the giant freshwater prawn Macrobrachium rosenbergii: Field and laboratory studies
International audienceChlordecone is a persistent organochlorine pesticide that has been widely used in Guadeloup
Lâoral aujourdâhui : perspectives didactiques
Il nâest plus temps aujourdâhui de sâinterroger sur la lĂ©gitimitĂ© dâun enseignement de lâoral : tous les programmes et plans dâĂ©tudes actuels des diffĂ©rents pays et rĂ©gions francophones lui donnent une place consĂ©quente, de la maternelle Ă la fin du secondaire, des premiers rituels langagiers aux genres les plus complexes. Ce nouvel ouvrage de la collection Recherches en didactique du français a dĂšs lors pour principal objectif - et intĂ©rĂȘt - de prĂ©senter des pistes et rĂ©alisations concrĂštes, fondĂ©es didactiquement. Celles-ci tĂ©moignent des avancĂ©es dans ce domaine, mais aussi du dĂ©veloppement dâune ingĂ©nierie didactique solidement argumentĂ©e, attentive aux dĂ©marches dâĂ©laboration et de validation des dispositifs proposĂ©s. Au-delĂ de certaines convergences, les contributions font apparaitre des maniĂšres diversifiĂ©es dâenvisager lâ « oral » comme objet de lâenseignement : des pratiques communicatives larges, multimodales, Ă des conduites langagiĂšres « transversales » telles la justification ou lâargumentation, dâun oral au service de lâĂ©crit Ă des approches spĂ©cifiquement centrĂ©es sur des genres oraux tels le dĂ©bat ou le documentaire, en production ou en comprĂ©hension. Lâouvrage aborde ainsi de nombreuses questions, notamment Ă propos des normes appliquĂ©es, ou Ă appliquer, lorsquâon enseigne lâoral, de lâĂ©valuation, des relations entre oral et Ă©crit, de la formation, voire de la dĂ©limitation mĂȘme du domaine. Il pointe aussi quelques lacunes qui demeurent, concernant la progression des apprentissages par exemple. Cet ouvrage est de nature Ă intĂ©resser les enseignant-e-s, qui pourront y trouver diverses pistes, les formateurs et formatrices, les didacticien-ne-s des langues et⊠tous les adeptes de lâoral, sous toutes ses formes et dans toutes ses variĂ©tĂ©s