Developing Strategic Marketing Plan

This publication is first in a series targeted for Coordinators and Managers within Benefits Planning, Assistance and Outreach Programs concerned with developing continuous quality improvement approaches. This early publication focuses on understanding strategies for market position, strategic planning and provides a tool for conducting an organizational self-assessment along with a stakeholder analysi

Taxonomy of the fouling cheilostome bryozoans, Schizoporella unicornis, (Johnston) and Schizoporella errata (Waters)

Figure 1. (A–D) Images of Wood's Pliocene specimen from the Coralline Crag, Suffolk (NHM B1675) described in Busk (1859). (A) Group of autozooids at growing edge of colony within small bivalve shell. (B) Autozooids exhibiting deep V-shaped sinus. (C) Frontal shield with paired avicularia and deep V-shaped sinus. (D) Detail of primary orifice and sinus. (E, F) Lectotype of Schizoporella unicornis [NHM 1847.16.174 (a)] bleached portion. (E) Group of autozooids at the distal edge of colony with adventitious avicularia, paired, single or absent. (F) Ovicellate autozooids showing radially aligned scalloped grooves. Scale bars: 500 µm (A); 250 µm (B); 100 µm (C, E); 50 µm (D,F).Published as part of Tompsett, Scott, Porter, Joanne S. & Taylor, Paul D., 2009, Taxonomy of the fouling cheilostome bryozoans Schizoporella unicornis (Johnston) and Schizoporella errata (Waters), pp. 2227-2243 in Journal of Natural History 43 (35-36) on page 2231, DOI: 10.1080/00222930903090140, http://zenodo.org/record/521715

Recent advances in malaria genomics and epigenomics

Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step changes in our understanding of malaria parasite (Plasmodium spp.) biology and its interactions with its host and vector. Driven by the availability of vast amounts of genome sequence data from Plasmodium species strains, relevant human populations of different ethnicities, and mosquito vectors, researchers can consider any biological component of the malarial process in isolation or in the interactive setting that is infection. In particular, considerable progress has been made in the area of population genomics, with Plasmodium falciparum serving as a highly relevant model. Such studies have demonstrated that genome evolution under strong selective pressure can be detected. These data, combined with reverse genetics, have enabled the identification of the region of the P. falciparum genome that is under selective pressure and the confirmation of the functionality of the mutations in the kelch13 gene that accompany resistance to the major frontline antimalarial, artemisinin. Furthermore, the central role of epigenetic regulation of gene expression and antigenic variation and developmental fate in P. falciparum is becoming ever clearer. This review summarizes recent exciting discoveries that genome technologies have enabled in malaria research and highlights some of their applications to healthcare. The knowledge gained will help to develop surveillance approaches for the emergence or spread of drug resistance and to identify new targets for the development of antimalarial drugs and perhaps vaccines

Reactive Molecular Dynamics Simulations of Shock Through a Single Crystal of Pentaerythritol Tetranitrate

Large-scale molecular dynamics simulations and the reactive force field ReaxFF were used to study shock-induced initiation in crystalline pentaerythritol tetranitrate (PETN). In the calculations, a PETN single crystal was impacted against a wall, driving a shockwave back through the crystal in the [100] direction. Two impact speeds (4 and 3 km/s) were used to compare strong and moderate shock behavior. The primary difference between the two shock strengths is the time required to exhibit the same qualitative behaviors with the lower impact speed lagging behind the faster impact speed. For both systems, the shock velocity exhibits an initial deceleration due to onset of endothermic reactions followed by acceleration due to the onset of exothermic reactions. At long times, the shock velocity reaches a steady value. After the initial deceleration period, peaks are observed in the profiles of the density and axial stress with the strongly shocked system having sharp peaks while the weakly shocked system developed broad peaks due to the slower shock velocity acceleration. The dominant initiation reactions in both systems lead to the formation of NO_2 with lesser quantities of NO_3 and formaldehyde also produced

Self-awareness of driving impairment in patients with cataract or glaucoma

This study compared the driving performance of individuals with the eye diseases cataracts or glaucoma with age-matched controls, as well as the individual’s own perceptions of driving. Participants included drivers over the age of 50 years who had been diagnosed with glaucoma (n=29) or cataracts (n=33) and a control group with no ocular pathology (n=13). Driving performance was measured on a closed road circuit using a range of standardised measures of vehicle control and hazard recognition and avoidance, while visual performance was measured with a battery of tests including visual acuity, contrast sensitivity and visual fields. Perceptions of vision and driving were assessed using the Activities of Daily Vision Scale, Driver Behaviour Questionnaire and a driving exposure questionnaire. Driving performance was significantly poorer (p<0.05) for each of the ocular disease groups compared to the control group. Impaired contrast sensitivity and the higher disease severity scores (for the glaucoma group only) correlated most strongly with poorer driving performance. While participants with cataracts rated their vision significantly more poorly than those in the glaucoma and control groups, there were no significant differences between the participant groups rating of their own driving performance. These findings suggest that there is no direct relationship between self-rated driving ability and actual vision and driving performance. This has serious road safety implications

Occupational Therapists\u27 Experiences with Ethical and Occupation-based Practice in Hospital Settings

Changes in health care delivery practices are impacting the provision of care in all venues. Occupational therapists working in hospital settings strive to meet professional mandates for occupation-based practice within a medical-model system. Ethical practice is another aspect of service provision vulnerable to contextual influences. The aims of the two studies reported here were to explore occupational therapists’ experiences with occupation-based practice, and with ethical issues, in hospital settings. Grounded theory methods were employed for both studies. Data were collected via individual, semi-structured interviews with 22 participants for the first study. For the second study, nine participants participated in individual, semi-structured interviews, journaling, and follow up interviews. Data analysis resulted in four emergent themes for each study. The main themes of the first study were Occupation-based practice expresses professional identity; Occupation-based practice is more effective; Occupation-based practice can be challenging in the clinic; and, Occupation-based practice takes creativity to adapt. The four themes of the second study were Anything less would be unethical: Key issues; I trust my gut: Affective dimension of ethical practice; Ethical practice is expected but challenging; and, It takes a village. Occupational therapists negotiate challenges inherent in contemporary hospital-based practice to provide occupation-based services and to practice ethically. Occupation-based practice is perceived to be more effective than biomedical approaches to intervention. Therapists must employ creative strategies to overcome challenges presented by medical-model service delivery contexts in order to provide occupation-based interventions. In comparison to other health care professionals working in adult rehabilitation practice, occupational therapists experience both common and unique ethical issues. A discovery of this study was that occupational therapists also experience ethical tensions related to team members’ and families’ sometimes subtle, and less frequently explicit, requests to falsify recommendations in documentation. Experiences with ethical issues include an inherent affective component in the form of moral distress and a strong sense of caring. The impact of systemic/organizational and relational forces is a reality that contemporary occupational therapists must negotiate in order to provide occupation-based and ethical practice

THE RELATIONSHIPS AMONG CREATIVITY, GRIT, ACADEMIC MOTIVATION, AND ACADEMIC SUCCESS IN COLLEGE STUDENTS

Creativity research is an underdeveloped area of educational psychology. For example, studies of students’ creativity as a predictor of academic achievement are uncommon in the field. Moreover, perseverance—which is an integral part of the definition of creativity (Sternberg, 2012)—is not typically measured in creativity research. To address these issues, the current study sought to discern within an academic context whether perseverance serves as a mediating factor between creativity and academic achievement. Two undergraduate student samples (N = 817; N = 187) participated in a survey measuring their creativity and perseverance. This multiple manuscript dissertation sought to examine the psychometric properties of a measure of creativity: the Runco Ideational Behavior Scale (RIBS) and a measure of perseverance: the Grit Scale and to explore the relationships between creativity, perseverance, academic motivation, and academic achievement. Study 1 found that the RIBS had a correlated two-factor structure with two subscales: the Scatterbrained Subscale and the Divergent Thinking Subscale. Grit had a correlated two-factor structure reflecting interest and effort, and this reinforced previous findings regarding this scale These two scales hold promise as measures of the creative process. Study 2 found that although traditional motivation measures consistently predicted grades, grit only predicted grades in one sample, and creativity had no relationship with grades. Creativity appears to be orthogonal to academic achievement as measured by grades. There was evidence that grit can mediate the relationships between motivation and grades, but only in one sample. This research shares the limitations of other self-report surveys, but the psychometrics behind the measures were strong. Future research should continue to examine creativity and perseverance as important noncognitive constructs in academic contexts especially among diverse populations

Evidence of Late Quaternary Fires from Charcoal and Siliceous Aggregates in Lake Sediments in the Eastern U.S.A.

The late-glacial transition to the Holocene, 15,000–11,600 cal yr BP, is an enigmatic period of dynamic global changes and a major extinction event in North America. Fire is an agent of disturbance that transforms the environment physically and chemically, and affects plant community composition. To improve understanding of the linkages between fire, vegetation, and climate over the late glacial and Holocene in the eastern U.S., I analyzed lake-sediment cores for charcoal and indicators of wood ash, and compared results to existing pollen records. A new microscopic charcoal record from Anderson Pond, Tennessee revealed high fire activity from 23,000–15,000 cal yr BP when conifers dominated, and during the Mid-Holocene Warm Period (8000–5200 cal yr BP), when hardwoods dominated. Macroscopic charcoal analysis of sediments from Pigeon Marsh, Georgia showed high fire activity from 16,500–14,500 cal yr BP, below a major hiatus. Jackson Pond, Kentucky and Cahaba Pond, Alabama had low macroscopic charcoal concentrations during the late glacial; largest charcoal peaks occurred around 5000 cal yr BP at Jackson Pond, and from 1370–640 cal yr BP at Cahaba Pond. Thin sections were prepared for cores from the four southeastern U.S. sites and from Swift and Slack Lakes, Michigan, and analyzed together with nitrogen isotopes and element data from XRF. Thin sections showed the presence of siliceous aggregates, a unique grain type, in sediments from five sites. These grains are rare, occurring in only three periods, around 19,250, 14,000 and 12,400 cal yr BP. In laboratory experiments, I produced siliceous aggregates from wood ash with simulated rain, and found their formation requires silt, but not high acidity. On the landscape, siliceous aggregates form after fires in wood ash by the action of water. The alkaline pH of the wet ash dissolves phytoliths, and amorphous silica nucleates around silt-sized quartz grains. Then aggregates are transported into lake sediments. My research demonstrates that siliceous aggregates are a new proxy for wildfires in paleoenvironmental records. The wildfire-derived siliceous aggregates in cores examined from the eastern U.S. are contemporaneous with combustion signals in Greenland ice cores, suggesting widespread late-glacial fire events

The Effectiveness Of Internal And External Mechanisms Of Corporate Control

This research reflects a recent trend toward the development of an overall understanding of corporate control. Previous research has examined CEO turnover and corporate takeovers separately. This research provides a more complete analysis of the corporate control of the firm conditioned on previous events over the period 1978 - 1988. Logistic regression analyses indicate that the probability of a takeover offer is highest for firms performing poorly which have not previously replaced their CEO. Debt, the percentages of stock held by the ceo or outside investor, and the existence of an antitakeover mechanism also affect the probability of a firm receiving a takeover offer. Results support the theory that external corporate control mechanisms do function when internal mechanisms have failed to function. Additionally, results suggest the external labor market is working to attract the CEO of a firm performing well