Langfristiges Wachstum durch Forschung und Innovation

Dietmar Harhoff, LMU und Expertenkommission Forschung und Innovation, sieht Handlungsbedarf bei der Innovationsfinanzierung und im Wissens- und Technologietransfer. Da Deutschland zu sehr auf inkrementelle und zu wenig auf radikale Innovationen setze, sollte das Steuersystem „eigenkapital- und innovationsfreundlicher“ und die Rahmenbedingungen für Wagniskapitalgeber verbessert werden. Im Bereich Technologietransfer sollte die Unterstützung von Public Private Partnerships ausgebaut, die Handhabung des Neuheitsschutzes im Patentrecht verbessert und die Beteiligung von Hochschulen an Ausgründungen erleichtert werden. Auch in der Innovationspolitik werde deutlich, dass der Staat durch bessere Rahmenbedingungen für Gründungen und radikale Neuerungen viel dazu beitragen könne, die langfristigen Wachstumsaussichten zu verbessern.Wirtschaftswachstum, Technischer Fortschritt, Forschungs- und Technologiepolitik, Wirtschaftspolitische Wirkungsanalyse, Deutschland

Impact of Criticality and Phase Separation on the Spin Dynamics of the One-Dimensional t–J Model

The recursion method is used to determine the T=0 spin dynamic structure factor S zz (q,ω) in the Luttinger liquid state and in the phase‐separated state of the one‐dimensional t–J model. As the exchange coupling increases from zero, the dispersions and line shapes of the dominant spin excitations are observed to undergo a major metamorphosis between the free‐fermion limit and the onset of phase separation. The familiar two‐spinon spectrum of the Heisenberg antiferromagnetic chain emerges gradually in the strongly phase‐separated state

Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival

Xenotransplantation using pig organs has achieved survival times up to 195 days in pig orthotopic heart transplantation into baboons. Here we demonstrate that in addition to an improved immunosuppressive regimen, non-ischaemic preservation with continuous perfusion and control of post-transplantation growth of the transplant, prevention of transmission of the porcine cytomegalovirus (PCMV) plays an important role in achieving long survival times. For the first time we demonstrate that PCMV transmission in orthotopic pig heart xenotransplantation was associated with a reduced survival time of the transplant and increased levels of IL-6 and TNF alpha were found in the transplanted baboon. Furthermore, high levels of tPA-PAI-1 complexes were found, suggesting a complete loss of the pro-fibrinolytic properties of the endothelial cells. These data show that PCMV has an important impact on transplant survival and call for elimination of PCMV from donor pigs

Bosonization of interacting fermions in arbitrary dimension beyond the Gaussian approximation

We use our recently developed functional bosonization approach to bosonize interacting fermions in arbitrary dimension $d$ beyond the Gaussian approximation. Even in $d=1$ the finite curvature of the energy dispersion at the Fermi surface gives rise to interactions between the bosons. In higher dimensions scattering processes describing momentum transfer between different patches on the Fermi surface (around-the-corner processes) are an additional source for corrections to the Gaussian approximation. We derive an explicit expression for the leading correction to the bosonized Hamiltonian and the irreducible self-energy of the bosonic propagator that takes the finite curvature as well as around-the-corner processes into account. In the special case that around-the-corner scattering is negligible, we show that the self-energy correction to the Gaussian propagator is negligible if the dimensionless quantities $( \frac{q_{c} }{ k_{F}} )^d F_{0} [ 1 + F_{0} ]^{-1} \frac{\mu}{\nu^{\alpha}} | \frac{ \partial \nu^{\alpha} }{ \partial \mu} |$ are small compared with unity for all patches $\alpha$. Here $q_{c}$ is the cutoff of the interaction in wave-vector space, $k_{F}$ is the Fermi wave-vector, $\mu$ is the chemical potential, $F_{0}$ is the usual dimensionless Landau interaction-parameter, and $\nu^{\alpha}$ is the {\it{local}} density of states associated with patch $\alpha$. We also show that the well known cancellation between vertex- and self-energy corrections in one-dimensional systems, which is responsible for the fact that the random-phase approximation for the density-density correlation function is exact in $d=1$, exists also in $d> 1$, provided (1) the interaction cutoff $q_{c}$ is small compared with $k_{F}$, and (2) the energy dispersion is locally linearized at the Fermi the Fermi surface. Finally, we suggest a new systematic method to calculate corrections to the RPA, which is based on the perturbative calculation of the irreducible bosonic self-energy arising from the non-Gaussian terms of the bosonized Hamiltonian.Comment: The abstract has been rewritten. No major changes in the text

Charge and spin dynamics in the one-dimensional t−Jzt-J_z and t−Jt-J models

The impact of the spin-flip terms on the (static and dynamic) charge and spin correlations in the Luttinger-liquid ground state of the 1D $t-J$ model is assessed by comparison with the same quantities in the 1D $t-J_z$ model, where spin-flip terms are absent. We employ the recursion method combined with a weak-coupling or a strong-coupling continued-fraction analysis. At $J_z/t=0^+$ we use the Pfaffian representation of dynamic spin correlations. The changing nature of the dynamically relevant charge and spin excitations on approach of the transition to phase separation is investigated in detail. The $t-J_z$ charge excitations (but not the spin excitations) at the transition have a single-mode nature, whereas charge and spin excitations have a complicated structure in the $t-J$ model. In the $t-J_z$ model, phase separation is accompanied by N\'eel long-range order, caused by the condensation of electron clusters with an already existing alternating up-down spin configuration (topological long-range order). In the $t-J$ model, by contrast, the spin-flip processes in the exchange coupling are responsible for continued strong spin fluctuations (dominated by 2-spinon excitations) in the phase-separated state.Comment: 11 pages (RevTex). 14 Figures available from author