Modelos de escaneo de gestión estratégica basados en tendencias heurísticas como cuantificadores intensivos de menor información

SS (Strategic Scanning) is unique, partially subjective, inconsistent, interdisciplinary, vague and multidimensional process. Its description and optimisation suffers from IS (Information Shortage) and heterogeneity. IS eliminates straightforward application of traditional statistical methods. Heterogeneity problems are caused by heterogeneous nature of scanned information structures. Artificial Intelligence has developed some tools to solve such problems. Qualitative reasoning is one of them. It is based on the least information intensive quantifiers i.e. trends. There are four different trends i.e. qualitative values and their derivatives: plus/increasing; zero/constant; negative/decreasing; any value / any trend. The paper studies SS models based on ELEs (Equationless Heuristics). An example of ELE is ¿ If novelity is increasing then confidence is decreasing. A solution of a qualitative model is represented by a set S of scenarios and a set T of time transitions among these scenarios. The key information input into an ELE model is subjective knowledge of experts. A consensus among SS experts is often not reached because of inconsistencies of experts¿ knowledge. The SS case study is 12 dimensional (e.g. Freshness, Relevance) and based on 12 ELEs. There are 29 scenariosSS (Strategic Scanning) es un proceso único, parcialmente subjetivo, inconsistente, interdisciplinario, vago y multidimensional. Su descripción y optimización adolece de IS (escasez de información) y heterogeneidad. IS elimina la aplicación directa de los métodos estadísticos tradicionales. Los problemas de heterogeneidad son causados por la naturaleza heterogénea de las estructuras de información escaneadas. La Inteligencia Artificial ha desarrollado algunas herramientas para resolver tales problemas. El razonamiento cualitativo es uno de ellos. Se basa en los cuantificadores que requieren menos información, es decir, las tendencias. Hay cuatro tendencias diferentes, es decir, valores cualitativos y sus derivados: más / creciente; cero / constante; negativo / decreciente; cualquier valor / cualquier tendencia. El artículo estudia los modelos SS basados en ELE (heurística sin ecuaciones). Un ejemplo de ELE es: si la novedad aumenta, la confianza disminuye. La solución de un modelo cualitativo está representada por un conjunto S de escenarios y un conjunto T de transiciones de tiempo entre estos escenarios. La entrada de información clave en un modelo ELE es el conocimiento subjetivo de los expertos. A menudo no se llega a un consenso entre los expertos en SS debido a inconsistencias en el conocimiento de los expertos. El estudio de caso de SS es de 12 dimensiones (por ejemplo, Frescura, Relevancia) y se basa en 12 ELE. Hay 29 escenarios.Universidad Pablo de Olavid

Alpha-gal syndrome – A case report of tick-borne anaphylactic shock

The most common cause of vasoplegic shock in critical care is sepsis. However, although rarely and only in specifically sensitised individuals previously bitten by a tick, red meat may provoke a delayed allergic reaction called an alpha-gal syndrome. We present a case of a protracted life-threatening manifestation of alpha-gal syndrome, which, due to an unusual absence of typical features of anaphylaxis can masquerade as septic shock and calls attention to the premature diagnostic closure as a contributor to diagnostic error. Alpha-gal syndrome is a relatively new, but increasingly recognised health issue. We propose that alpha-gal syndrome should be considered in the differential diagnosis of vasoplegic shock of unclear aetiology even in the absence of typical allergic symptomatology and typical allergen exposure since alpha-gal is present in a wide variety of carriers

Walking Outcome After Traumatic Paraplegic Spinal Cord Injury: The Function of Which Myotomes Makes a Difference?

BACKGROUND: Accurate prediction of walking function after a traumatic spinal cord injury (SCI) is crucial for an appropriate tailoring and application of therapeutical interventions. Long-term outcome of ambulation is strongly related to residual muscle function acutely after injury and its recovery potential. The identification of the underlying determinants of ambulation, however, remains a challenging task in SCI, a neurological disorder presented with heterogeneous clinical manifestations and recovery trajectories. OBJECTIVES: Stratification of walking function and determination of its most relevant underlying muscle functions based on stratified homogeneous patient subgroups. METHODS: Data from individuals with paraplegic SCI were used to develop a prediction-based stratification model, applying unbiased recursive partitioning conditional inference tree (URP-CTREE). The primary outcome was the 6-minute walk test at 6 months after injury. Standardized neurological assessments ≤15 days after injury were chosen as predictors. Resulting subgroups were incorporated into a subsequent node-specific analysis to attribute the role of individual lower extremity myotomes for the prognosis of walking function. RESULTS: Using URP-CTREE, the study group of 361 SCI patients was divided into 8 homogeneous subgroups. The node specific analysis uncovered that proximal myotomes L2 and L3 were driving factors for the differentiation between walkers and non-walkers. Distal myotomes L4-S1 were revealed to be responsible for the prognostic distinction of indoor and outdoor walkers (with and without aids). CONCLUSION: Stratification of a heterogeneous population with paraplegic SCI into more homogeneous subgroups, combined with the identification of underlying muscle functions prospectively determining the walking outcome, enable potential benefit for application in clinical trials and practice

Letter to H.B. Stenzel from Jiri Kriz on 1965-10-06

Jackson School of Geoscience

Letter to H.B. Stenzel from Jiri Kriz on 1965-09-23

Jackson School of Geoscience

Cephalopod limestone biofacies in the Silurian of the Prague Basin, Bohemia

The biostratinomy of Silurian cephalopod limestone biofacies of the Prague Basin is interpreted. Two facies types are recognized. One is the result of a surface current and the other one is the effect of redeposition within the current itself in a shallower environment during storm events. Orientation of cephalopod shells in these two facies types is discussed in relation to the Prague Basin development and to phenomena like telescoping, trap-structures and geopetal structures

Faecal microbiota transplantation for multidrug-resistant organism decolonization in spinal cord injury patients: a case series

Summary: Introduction: The increase of multidrug-resistant (MDR) bacteria in healthcare settings is a worldwide concern. Isolation precautions must be implemented to control the significant risk of transmitting these pathogens among patients. Antibiotic decolonization is not recommended because of the threat of increasing antibiotic resistance. However, restoring gut microflora through faecal microbiota transplantation (FMT) is a hopeful solution. Patients and method: In 2019–2022, FMT was indicated in seven patients of the Spinal Cord Unit at University Hospital Motol who were colonized with MDR bacterial strains. Five patients tested positive for carriage of carbapenemase-producing Enterobacteriaceae, and two were carriers of vancomycin-resistant enterococci. Isolation measures were implemented in all patients. Donor faeces were obtained from healthy, young, screened volunteers. According to local protocol, 200–300 ml of suspension was applied through a nasoduodenal tube. Results: The mean age of the patients was 43 years. The mean length of previous hospital stay was 93.2 days. All patients were treated with broad-spectrum antibiotics for infectious complications before detecting colonisation with MDR bacteria. MDR organism decolonization was achieved in five patients, and consequently, isolation measures could be removed. Colonization persisted in two patients, one of whom remained colonized even after a third FMT. No adverse events were reported after FMT. Conclusion: FMT is a safe and effective strategy to eradicate MDR bacteria, even in spinal cord injured patients. FMT can allow relaxation of isolation facilitates, the participation of patients in a complete rehabilitation program, their social integration, and transfer to follow-up rehabilitation centres

Popularizace vysledku ceskeho geologickeho vyzkumu formou videoporadu.

Supplement: 2 videocasettes (the films Mission in the region of vulcanos; The State Geological Service of the CR and environment).Available from STL Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi

Joachim Barrande - popularne naucny videofilm - 200. vyroci.

Supplement: 1 videocasette (film Barrande in Bohemia).Available from STL Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi