667 research outputs found

    Efficient Data Gathering in Wireless Sensor Networks Based on Matrix Completion and Compressive Sensing

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    Gathering data in an energy efficient manner in wireless sensor networks is an important design challenge. In wireless sensor networks, the readings of sensors always exhibit intra-temporal and inter-spatial correlations. Therefore, in this letter, we use low rank matrix completion theory to explore the inter-spatial correlation and use compressive sensing theory to take advantage of intra-temporal correlation. Our method, dubbed MCCS, can significantly reduce the amount of data that each sensor must send through network and to the sink, thus prolong the lifetime of the whole networks. Experiments using real datasets demonstrate the feasibility and efficacy of our MCCS method

    Regulatory T Cell in Stroke: A New Paradigm for Immune Regulation

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    Stroke is a common, debilitating trauma that has an incompletely elucidated pathophysiology and lacks an effective therapy. FoxP3+CD25+CD4+ regulatory T cells (Tregs) suppress a variety of normal physiological and pathological immune responses via several pathways, such as inhibitory cytokine secretion, direct cytolysis induction, and antigen-presenting cell functional modulation. FoxP3+CD25+CD4+ Tregs are involved in a variety of central nervous system diseases and injuries, including axonal injury, neurodegenerative diseases, and stroke. Specifically, FoxP3+CD25+CD4+ Tregs exert neuroprotective effects in acute experimental stroke models. These beneficial effects, however, are difficult to elucidate. In this review, we summarized evidence of FoxP3+CD25+CD4+ Tregs as potentially important immunomodulators in stroke pathogenesis and highlight further investigations for possible immunotherapeutic strategies by modulating the quantity and/or functional effects of FoxP3+CD25+CD4+ Tregs in stroke patients

    A Promising New Anti-Cancer Strategy: Iron Chelators Targeting CSCs

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    Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings

    Intelligent methods for optimization design of lightweight fiber-reinforced composite structures: A review and the-state-of-the-art

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    As the application of lightweight fiber-reinforced composite structures reaches an unprecedented scale in industry, design technology for composite structures becomes crucial for enhancing performance, improving productivity, and reducing cost. In recent years, the rapid development of intelligent technology, such as big data, deep learning, and machine learning, has promoted the development of design technology. However, the current situation and intellectualization of the design technology is not well summarized. This paper reviews the advance in design technologies for fiber-reinforced composite structures, including prediction and optimization methods for composite properties. Then, their intellectualization development is overviewed. Finally, the development trend of intelligent design technologies and intelligent composite structures are discussed. This work can provide a reference for researchers in the related field

    Current Status and Prospect of Membrane-Based Offshore Floating Photovoltaic Technology

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    [Introduction] The research and development of offshore floating photovoltaic complies with the needs of national energy strategic development, caters to the background of industry development led by science and technology, and helps the development of emerging economic industrial chain. This paper aims to deeply explore the main components and core technologies of offshore floating photovoltaic system, and provide a theoretical basis for the development of offshore floating photovoltaic in China. [Method] Based on the existing research on offshore floating photovoltaic at home and abroad, this paper refined the relevant construction technology of flexible photovoltaic, verified the commercial feasibility of offshore floating photovoltaic development, introduced the configuration and composition of large-scale offshore floating photovoltaic (LOFPV) system, expounded the hydrodynamic design theory and method basis of flexible membrane structure and mooring system, and showed the typical engineering practice of offshore floating photovoltaic. [Result] Offshore flexible membrane-based floating photovoltaic has many advantages, such as lightweight, miniaturization, high power exchange efficiency and flexible configuration. In addition, the membrane structure is foldable, convenient for transportation, and convenient for installation, and the overall structure has no complex connector, so the system has high reliability and is convenient for operation and maintenance. Relevant achievements of this paper will provide great reference value for the development of China's offshore floating photovoltaic technology. [Conclusion] The functionality and reliability of flexible membrane-based floating photovoltaic construction technology are explained, and this flexible membrane structure will definitely be an important application type of offshore floating photovoltaic in the future
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