2 research outputs found
Metal-Free Synthesis of 2‑Aminobenzothiazoles via Aerobic Oxidative Cyclization/Dehydrogenation of Cyclohexanones and Thioureas
A metal-free process for the synthesis of 2-aminobenzothiazoles from cyclohexanones and thioureas has been developed using catalytic iodine and molecular oxygen as the oxidant under mild conditions. Various 2-aminobenzothiazoles, 2-aminonaphtho[2,1-<i>d</i>]thiazoles, and 2-aminonaphtho[1,2-d]thiazoles were prepared via this method in satisfactory yields
Palladium-Catalyzed Coupling of Alkynes with Unactivated Alkenes in Ionic Liquids: A Regio- and Stereoselective Synthesis of Functionalized 1,6-Dienes and Their Analogues
A palladium-catalyzed
regio- and stereoselective intermolecular
tandem reaction of alkynes and unactivated 1,6-enols in ionic liquids
is described, providing a practical, efficient, and versatile method
for the synthesis of functionalized 1,6-dienes in moderate to good
yields. The present reaction has high functional-group tolerance and
gives products on a gram scale. Mechanistic studies indicate that
the reaction might proceed via a chain-walking mechanism