261 research outputs found
Primary Exploration on the Development of Public Leisure Sport with Chinese Characteristics
The 21st century is an era featuring public leisure sport. With the continuous improvements of social living standards, leisure sport has gradually won the favor and attention of the public. Globally, due to the differences in thinking, value, manners, and customs, leisure sport in China and Western countries are quite different in terms of both form and content. While the flourish of leisure sport in China is an inexorable trend of social progress, it is also undeniable that currently the development of leisure sport in China is still facing difficulties and challenges. To achieve long-term development of leisure sport in China, it is necessary to analyze issues depending on specific situations, build a leisure sport-related theory system with Chinese characteristics in line with the national conditions, vigorously develop national and public sport events, and guide the public to do sports in a scientific and reasonable manner
Monitoring of the 2008 Chaitén Eruption Cloud Using MODIS Data and its Impacts
This chapter presents the monitoring of the 2008 Chaitén eruption cloud using Moderate Resolution Imaging Spectroradiometer (MODIS) data and its impacts. The 8-day MODIS data from 3 to 10 May 2008 were used to track the movement and dispersion of the eruption cloud of the Chaitén volcano in Chile following the eruption on 2 May 2008. For detecting volcanic particulates, the procedure is adopted based on the brightness temperature difference (BTD) algorithm, by which the thermal infrared channels were centered on 11–12 μm of multispectral satellite sensors. The BTD is generally negative for volcanic ash but positive for ice and water vapor. The eruption cloud was found to drift northeastward, eastward, and southeastward crossing the central and northern part of Argentina and over the Atlantic Ocean. The timing of heavy rainfall in South Africa during May–June, in central Australia during June 2008 and in Hong Kong during June (the wettest since record began in 1884), was considered to have been connected to the dispersion of the particulates from this Chaitén eruption to further impact downstream
Preparation and Identification of α-Amylase Inhibitory Peptides from Mung Bean Protein
In this study, sequential hydrolysis with pepsin followed by trypsin was conducted on total protein and protein fractions from mung bean. The difference in α-amylase inhibitory activity among the resulting hydrolysates was compared and the underlying reason was analyzed in terms of degree of hydrolysis, amino acid composition and molecular mass. The results showed that the total protein hydrolysate had the highest α-amylase inhibitory activity (16.51%). Compared with its fractions, the total protein showed the highest content of hydrophobic amino acids (32.68%) and degree of hydrolysis (6.28%), and the molecular mass of its hydrolysate was the lowest (< 20 kDa). Therefore, the total protein was selected to prepare α-amylase inhibitory peptides. Finally, 17 peptides with potential α-amylase inhibitory activity were discovered by the isolation and identification of peptides from mung bean protein. This study suggests that mung bean protein is a better food source of α-amylase inhibitory peptides than its protein fractions, which can be used in blood glucose-lowering functional foods or drugs
Bis{2,4-dibromo-6-[(2-phenylethyl)iminomethyl]phenolato-κ2 N,O}cobalt(II)
In the title complex, [Co(C15H12Br2NO)2], the CoII atom is four-coordinated by two N,O-bidentate chelate Schiff base ligands, displaying a flattened tetrahedral coordination environment. The CoII atom occupies a special position on a twofold rotation axis. In the crystal, molecules are linked via weak C—H⋯Br interactions
Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma
miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells
Cisplatin resistance is a major cause of treatment failure in advanced ovarian cancer. The limited evidence shows the paradoxical regulation of miR-205 on chemotherapy resistance in cancer. Herein, we found that miR-205-5p was enormously increased in cisplatin-resistant C13K ovarian cancer cells compared with its cisplatin-sensitive OV2008 parental cells using miRNA microarrays, which was further verified by quantitative PCR. Furthermore, we confirmed that inhibition of miR-205-5p upregulated PTEN and subsequently attenuated its downstream target p-AKT, which inversed C13K cells from cisplatin resistance to sensitivity. Our data suggest that miR-205-5p contributes to cisplatin resistance in C13K ovarian cancer cells may via targeting PTEN/AKT pathway
STAT3 associates with vacuolar H<sup>+</sup>-ATPase and regulates cytosolic and lysosomal pH
Controlling mass and energy diffusion with metamaterials
Diffusion driven by temperature or concentration gradients is a fundamental
mechanism of energy and mass transport, which inherently differs from wave
propagation in both physical foundations and application prospects. Compared
with conventional schemes, metamaterials provide an unprecedented potential for
governing diffusion processes, based on emerging theories like the
transformation and the scattering cancellation theory, which enormously
expanded the original concepts and suggest innovative metamaterial-based
devices. We hereby use the term ``diffusionics'' to generalize these remarkable
achievements in various energy (e.g., heat) and mass (e.g., particles and
plasmas) diffusion systems. For clarity, we categorize the numerous studies
appeared during the last decade by diffusion field (i.e., heat, particles, and
plasmas) and discuss them from three different perspectives: the theoretical
perspective, to detail how the transformation principle is applied to each
diffusion field; the application perspective, to introduce various intriguing
metamaterial-based devices, such as cloaks and radiative coolers; and the
physics perspective, to connect with concepts of recent concern, such as
non-Hermitian topology, nonreciprocal transport, and spatiotemporal modulation.
We also discuss the possibility of controlling diffusion processes beyond
metamaterials. Finally, we point out several future directions for diffusion
metamaterial research, including the integration with artificial intelligence
and topology concepts.Comment: This review article has been accepted for publication in Rev. Mod.
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