産業医科大学の構内および周辺地域の植生概観, および構内の環境保全について

The Kitakyushu City area, in which the University of Occupational and Envionmental Health, Japan (UOEH) campus lies, is situated in the region of the evergreen broad-leaf, or laurel-leaf, forests. Our studies on relict forest stands revealed that the original forest communities in the area were Cyrtomio-Litseetum japonicae and Euonymo-Pittos-poretum tobirae in the coastl area, Arisemato ringentis-Machiletum thunbergii in the bottomland, Symploco-Castanopsietum sieboldii and Ardisio-Castanopsietum sieboldii in. foothill area, and Distylio-Cyclobalanopsietum stenophyllae, Actinodaphnetum lancifoliae and Skimmio-Cyclobalanopsietum acutae on the mountain slopes. The secondary forests in the area are Castanopsis-Cyclobalanopsis coppice of sprout origin, red-pine forest and deciduous forests of various dominants. The original forest on the UOEH campus is assumed to be Symploco-Castanopsietum sieboldii, an evergreen broad-leaf forest, some 25m high and I m dbh in canopy trees. The secondary forest on the campus is doin inated by Quercus serrata, accompanied by Rhus succedanea, Platycarya strobilacea and Castanopsis cuspidata var. sieholdii. A small wetland near the north gate is dominated by Typha angustata. Slopes on the campus, which were created by cutting-off or fillingup of the ground, are invaded by Miscanthus sinensis, Solidago altissima (alien) and many other herbaceous plants. One hundred and thirty-six species of flowering plants and eight specles of ferns were recorded from the campus. Conservation problems are discussed from the standpoint of vegetation science.1)医生ケ丘をふくむ北九州市西部は, 全域が照葉樹林域にある. 残存林分の調査によって, 沿岸地帯-内陸の原植生が推定され, 医生ケ丘一帯はスダシイ-ミミズバイ群集域であることが明らかとなった. 2)現存植生の二次林は, シイーカシ萌芽林とカラスザンショウ群落が優勢である. 医生ケ作の二次林では, コナラが優占し, ハゼノキ・ノグルミが常に出現する. 向陽地では林床にウラジロまたはコシダが優占している. 3)湿地にはガマ・ヒメガマ・イグサが優占する. 4)医生ケ丘で種子植物131種, シダ植物8種を記録した. 5)大学構内の緑化について, 植生学の立場から付言し, 特に残存林および西北部の湿原群落の保存の重要性を指摘した

産業医科大学の構内および周辺地域の植生概観, および構内の環境保全について

The Kitakyushu City area, in which the University of Occupational and Envionmental Health, Japan (UOEH) campus lies, is situated in the region of the evergreen broad-leaf, or laurel-leaf, forests. Our studies on relict forest stands revealed that the original forest communities in the area were Cyrtomio-Litseetum japonicae and Euonymo-Pittos-poretum tobirae in the coastl area, Arisemato ringentis-Machiletum thunbergii in the bottomland, Symploco-Castanopsietum sieboldii and Ardisio-Castanopsietum sieboldii in. foothill area, and Distylio-Cyclobalanopsietum stenophyllae, Actinodaphnetum lancifoliae and Skimmio-Cyclobalanopsietum acutae on the mountain slopes. The secondary forests in the area are Castanopsis-Cyclobalanopsis coppice of sprout origin, red-pine forest and deciduous forests of various dominants. The original forest on the UOEH campus is assumed to be Symploco-Castanopsietum sieboldii, an evergreen broad-leaf forest, some 25m high and I m dbh in canopy trees. The secondary forest on the campus is doin inated by Quercus serrata, accompanied by Rhus succedanea, Platycarya strobilacea and Castanopsis cuspidata var. sieholdii. A small wetland near the north gate is dominated by Typha angustata. Slopes on the campus, which were created by cutting-off or fillingup of the ground, are invaded by Miscanthus sinensis, Solidago altissima (alien) and many other herbaceous plants. One hundred and thirty-six species of flowering plants and eight specles of ferns were recorded from the campus. Conservation problems are discussed from the standpoint of vegetation science.1)医生ケ丘をふくむ北九州市西部は, 全域が照葉樹林域にある. 残存林分の調査によって, 沿岸地帯-内陸の原植生が推定され, 医生ケ丘一帯はスダシイ-ミミズバイ群集域であることが明らかとなった. 2)現存植生の二次林は, シイーカシ萌芽林とカラスザンショウ群落が優勢である. 医生ケ作の二次林では, コナラが優占し, ハゼノキ・ノグルミが常に出現する. 向陽地では林床にウラジロまたはコシダが優占している. 3)湿地にはガマ・ヒメガマ・イグサが優占する. 4)医生ケ丘で種子植物131種, シダ植物8種を記録した. 5)大学構内の緑化について, 植生学の立場から付言し, 特に残存林および西北部の湿原群落の保存の重要性を指摘した

北九州市北西部および近隣地における森林植生の傾度

Fifty forest stands and sixty plant species were ordinated by a reciprocal averaging (RA) method to extract the major vegetation patterns of the forest in northwestern Kitakyushu City and nearby areas. The RA stand ordination on the first and second axes revealed three gradients of vegetation. They are the gradienLs (1) from the Quercus serrata-dominatcd forest to the Machilus thunbergii- or Aphananthe aspera-dominated forest, (2) from the Quercus- to the Castanopsis cuspidata-dominated forest, and (3) from the Aphananthe- or the Machilus- to the Casianopsis-dominated forest. The first two gradients showed high correlations of the stand RA scores to the canopy height and to the number of species found in the stand, but the third one did not. The former two, therefore, were referred toas the successional series of forests on the moist (bottomland) habitat and that on the less moist (foothill) one, respectively, and the third as the environmental gradient from moist to less moist habitats in matured forests. The RA species ordination showed the distribution center of each species in the above rnentioned patterns of the forest vegetation(Received 15 February 1984)医生ケ丘をふくむ北九州市北西部および近隣地において, 森林群落50スタンドを調査した. それらを優占種により分類すると, コナラ群落, タブノキ群落, ムクノキ群落, シイノキ群落であった. 50スタンド, 60種の群落資料を反復平均法により解析した結果, 次の三つの植生の系列が明らかとなった. (i)コナラ群落一タブノキ群落-ムクノキ群落, (ii)コナラ群落-シイノキ群落, (iii)タブノキおよびムクノキ群落-シイノキ群落. 前2系列は樹高の増大および種類の増加と有意の相関をもつ森林の群落遷移の系列であり, 第3の系列ではそれらと相関がなく, 環境傾度上の系列であることが明らかとなった

INVOLVEMENT OF HUMAN HEPATIC UGT1A1, UGT2B4, AND UGT2B7 IN THE GLUCURONIDATION OF CARVEDILOL

This article is available online at http://dmd.aspetjournals.org ABSTRACT: Carvedilol ((؎)-1-carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol) is metabolized primarily into glucuronide conjugates. In the present study, we identified the human UDPglucuronosyltransferase (UGT) isoforms involved in the glucuronidation of carvedilol by thin-layer chromatography using microsomes from human liver or insect cells expressing recombinant UGT isoforms. We observed two forms of carvedilol glucuronides, namely G1 and G2, in hepatic microsomes. The glucuronidation of carvedilol was catalyzed by at least three recombinant UGT isoforms: UGT1A1, UGT2B4, and UGT2B7. UGT2B4 formed both G1 and G2, whereas UGT1A1 and UGT2B7 were responsible for the formation of glucuronide G2 and G1, respectively. The enzyme kinetics for carvedilol glucuronidation by UGT1A1, UGT2B4, and UGT2B7 in addition to human liver microsomes were examined by Lineweaver-Burk analysis. The values of K m and V max for human liver microsomes were 26.6 M and 106 pmol/min/mg protein for G1, and 46.0 M and 44.5 pmol/min/mg protein for G2, respectively. The K m values for UGT1A1, UGT2B4, and UGT2B7 for G1 and G2 (22.1-55.1 M) were comparable to those of the liver microsomes, whereas the V max values were in the range of 3.33 to 7.88 pmol/min/mg protein. The K m and V max /K m values for UGT2B4 and UGT2B7 for G1 were similar, whereas UGT2B4 had lower Km and higher V max /K m values for G2 compared with those of UGT1A1. These results suggest that G1 formation is catalyzed by UGT2B4 and UGT2B7, whereas G2 is formed by UGT2B4 and UGT1A1. These three hepatic UGT isoforms may have important roles in carvedilol metabolism