785 research outputs found
Absence of a transport signature of spin-orbit coupling in graphene with indium adatoms
Enhancement of the spin-orbit coupling in graphene may lead to various
topological phenomena and also find applications in spintronics. Adatom
absorption has been proposed as an effective way to achieve the goal. In
particular, great hope has been held for indium in strengthening the spin-orbit
coupling and realizing the quantum spin Hall effect. To search for evidence of
the spin-orbit coupling in graphene absorbed with indium adatoms, we carry out
extensive transport measurements, i.e., weak localization magnetoresistance,
quantum Hall effect and non-local spin Hall effect. No signature of the
spin-orbit coupling is found. Possible explanations are discussed.Comment: 5 pages, 4 figures, with supplementary material
Semantic Bimodal Presentation Differentially Slows Working Memory Retrieval
Although evidence has shown that working memory (WM) can be differentially affected by the multisensory congruency of different visual and auditory stimuli, it remains unclear whether different multisensory congruency about concrete and abstract words could impact further WM retrieval. By manipulating the attention focus toward different matching conditions of visual and auditory word characteristics in a 2-back paradigm, the present study revealed that for the characteristically incongruent condition under the auditory retrieval condition, the response to abstract words was faster than that to concrete words, indicating that auditory abstract words are not affected by visual representation, while auditory concrete words are. Alternatively, for concrete words under the visual retrieval condition, WM retrieval was faster in the characteristically incongruent condition than in the characteristically congruent condition, indicating that visual representation formed by auditory concrete words may interfere with WM retrieval of visual concrete words. The present findings demonstrated that concrete words in multisensory conditions may be too aggressively encoded with other visual representations, which would inadvertently slow WM retrieval. However, abstract words seem to suppress interference better, showing better WM performance than concrete words in the multisensory condition
The Design of Nonlinear Chirp Based on the DSP Builder Technique
This paper, by analyzing the function Chirp, studies the software design and realization of the function. It offers a design plan based on the nonlinear Chirp signal of DSP Builder technique and designs the signal generator of the nonlinear Chirp based on the design flow of Matlab/Simulink/DSP Builder/Quartusll. It also conducts simulation verification using the development software Matlab/Simulink and Quartusll, proving that the design can well realize the signal source Chirp. The experiment proves that the DSP Builder technique can modify the starting frequency, bandwidth and the frequency resolution of linear frequency modulation signals by changing the programming parameters. The method is proved to be simple in designing, convenient in modification, low in cost and it doesn’t involve any programming; therefore, it is easy to realize
Numerical and Experimental Study on the Multiobjective Optimization of a Two-Disk Flexible Rotor System
With the ever-increasing requirement for the thrust to weight ratio, the rotational speed of modern aeroengine is increasingly improved; thus most of the aeroengine rotor is flexible. Some dynamic problems, such as excessive vibration, appear due to the increase of the rotation speed of the aeroengine. The aim of this study is to reduce the vibration level of the flexible rotor system through optimum design. A laboratory scale two-disk flexible rotor system representing a typical aeroengine rotor system is designed. A combinational optimization strategy coupling the rotordynamics calculation software ANSYS and the multidisciplinary optimization software ISIGHT is proposed to optimize the rotor system. The positions of the disks are selected as the design variables. Constraints are imposed on critical speeds. The disks’ amplitudes and bearings’ transmitted forces are chosen as the optimization objectives. Using this strategy, the optimal positions of the two disks are obtained. The numerical optimization results are verified by the experiments based on the test rig. The results show a significant vibration level reduction after optimization
microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma.
Glycolysis was reported to have a positive correlation with radioresistance. Our previous study found that the miR-33a functioned as a tumor suppressor in malignant melanoma by targeting hypoxia-inducible factor1-alpha (HIF-1α), a gene known to promote glycolysis. However, the role of miR-33a-5p in radiosensitivity remains to be elucidated. We found that miR-33a-5p was downregulated in melanoma tissues and cells. Cell proliferation was downregulated after overexpression of miR-33a-5p in WM451 cells, accompanied by a decreased level of glycolysis. In contrast, cell proliferation was upregulated after inhibition of miR-33a-5p in WM35 cells, accompanied by increased glycolysis. Overexpression of miR-33a-5p enhanced the sensitivity of melanoma cells to X-radiation by MTT assay, while downregulation of miR-33a-5p had the opposite effects. Finally, in vivo experiments with xenografts in nude mice confirmed that high expression of miR-33a-5p in tumor cells increased radiosensitivity via inhibiting glycolysis. In conclusions, miR-33a-5p promotes radiosensitivity by negatively regulating glycolysis in melanoma
- …