Forest plot for the association of NF-κB with clinicopathological parameters.

<p>(A) Patients with adenocarcinoma and squamous cell carcinoma. (B) Patients with tumor stage T1/T2 and T3/T4. (C) Patients with or without lymph node metastasis. OR, Odds ratio; CI, confidence interval.</p

Flow illustration for studies selection process.

<p>Flow illustration for studies selection process.</p

Sensitivity analyses.

<p>(A) Overall survival in NSCLC patients. (B) Tumor stage. (C) Lymph node metastasis.</p

Forest plot for the association between NF-κB and overall survival in NSCLC patients.

<p>(A) Overall analysis of all NSCLC patients. (B) Subgroup analysis of Asian and Caucasian NSCLC patients. HR, hazard ratio; CI, confidence interval.</p

Main characteristics of included studies in the meta-analysis.

<p>Main characteristics of included studies in the meta-analysis.</p

Forest plot for the expression levels of NF-kB family members and 5-year overall survival in NSCLC patients.

<p>Forest plot for the expression levels of NF-kB family members and 5-year overall survival in NSCLC patients.</p

Additional file 1 of Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca2+ axis

Additional file 1. Fig. S1. Erbin deficiency facilitates NLRP3 inflammasome activation and pyroptosis of microglia in vivo and vitro. Fig. S2. Erbin regulates pyroptosis via IRE1α/Xbp1s/Ca2+ in vivo and vitro. Fig. S3. Erbin inhibits pyroptosis via IRE1α/Xbp1s/Ca2+ in BV2 cells and improves synaptic proteins by inhibiting IRE1α/Xbp1s pathway. Fig. S4. LPS/nigericin stimulation resulted in decreased TXNIP protein levels regardless of Erbin knockdown in BV2 cells

Additional file 3: Figure S1. of Institute collection and analysis of Nanobodies (iCAN): a comprehensive database and analysis platform for nanobodies

The workflow of iCAN website. After the user’s Web browser sends a HTTP query, the required HTML pages are returned in response to user’s query. (PDF 294 kb

Additional file 2: of Institute collection and analysis of Nanobodies (iCAN): a comprehensive database and analysis platform for nanobodies

Structure and Submit pages of iCAN website. (a) Structure page of iCAN (b) Submit page of iCAN. (PDF 639 kb

Additional file 4: Figure S2. of Institute collection and analysis of Nanobodies (iCAN): a comprehensive database and analysis platform for nanobodies

all data.xls: the source data of all curated nanobody. (XLS 2544 kb