Simultaneous VLBI Astrometry of H2O and SiO Masers toward the Semiregular Variable R Crateris

We obtained, for the first time, astrometrically registered maps of the 22.2 GHz H2O and 42.8, 43.1, and 86.2 GHz SiO maser emission toward the semiregular b-type variable (SRb) R Crateris, at three epochs (2015 May 21, and 2016 January 7 and 26) using the Korean Very-long-baseline Interferometry Network. The SiO masers show a ring-like spatial structure, while the H2O maser shows a very asymmetric one-side outflow structure, which is located at the southern part of the ring-like SiO maser feature. We also found that the 86.2 GHz SiO maser spots are distributed in an inner region, compared to those of the 43.1 GHz SiO maser, which is different from all previously known distributions of the 86.2 GHz SiO masers in variable stars. The different distribution of the 86.2 GHz SiO maser seems to be related to the complex dynamics caused by the overtone pulsation mode of the SRb R Crateris. Furthermore, we estimated the position of the central star based on the ring fitting of the SiO masers, which is essential for interpreting the morphology and kinematics of a circumstellar envelope. The estimated stellar coordinate corresponds well to the position measured by Gaia

Reduced glutamine synthetase activity alters the fecundity of female Bactrocera dorsalis (Hendel)

Glutamine synthetase (GS) is a key enzyme in glutamine synthesis and is associated with multiple physiological processes in insects, such as embryonic development, heat shock response, and fecundity regulation. However, little is known about the influence of GS on female fecundity in the oriental fruit fly, Bactrocera dorsalis. Based on the cloning of BdGSs, mitochondrial BdGSm and cytoplasmic BdGSc, we determined their expressions in the tissues of adult B. dorsalis. BdGSm was highly expressed in the fat body, while BdGSc was highly expressed in the head and midgut. Gene silencing by RNA interference against two BdGSs isoforms suppressed target gene expression at the transcriptional level, leading to a reduced ovarian size and lower egg production. The specific inhibitor L-methionine S-sulfoximine suppressed enzyme activity, but only the gene expression of BdGSm was suppressed. A similar phenotype of delayed ovarian development occurred in the inhibitor bioassay. Significantly lower expression of vitellogenin and vitellogenin receptor was observed when GS enzyme activity was suppressed. These data illustrate the effects of two GS genes on adult fecundity by regulating vitellogenin synthesis in different ways

Production of Transgenic Cloned Miniature Pigs with Membrane-bound Human Fas Ligand (FasL) by Somatic Cell Nuclear Transfer

Cell-mediated xenograft rejection, including NK cells and CD8+ CTL, is a major obstacle in successful pig-to-human xenotransplantation. Human CD8+ CTL and NK cells display high cytotoxicity for pig cells, mediated at least in part by the Fas/FasL pathway. To prevent cell-mediated xenocytotoxicity, a membrane-bound form of human FasL (mFasL) was generated as an inhibitor for CTL and NK cell cytotoxicity that could not be cleaved by metalloproteinase to produce putative soluble FasL. We produced two healthy transgenic pigs harboring the mFasL gene via somatic cell nuclear transfer (SCNT). In a cytotoxicity assay using transgenic clonal cell lines and transgenic pig ear cells, the rate of CD8+ CTL-mediated cytotoxicity was significantly reduced in transgenic pig's ear cells compared with that in normal minipig fetal fibroblasts. Our data indicate that grafts of transgenic pigs expressing membrane-bound human FasL control the cellular immune response to xenografts, creating a window of opportunity to facilitate xenograft survival

Microscopic model realization of d\boldsymbol{d}-wave pseudospin current order in Sr2_{\boldsymbol{2}}IrO4_{\boldsymbol{4}}

The $d$-wave pseudospin current order ($d$PSCO) with staggered circulating pseudospin current has been proposed as the hidden electronic order to describe the unexpected breaking of spatial symmetries in stoichiometric Sr$_{2}$IrO$_{4}$ and the unconventional pseudogap phenomena in electron doped Sr$_{2}$IrO$_{4}$. However, a microscopic model for the emergence of $d$PSCO is still lacking. The nearest neighbor Coulomb repulsion $V$, which is expected to be significant in Sr$_{2}$IrO$_{4}$ due to the large spatial extension of the Ir $5d$ orbitals, is capable of driving $d$PSCO on the mean-field level, albeit the latter is energetically degenerate to the staggered flux phase with circulating charge current. We find the in-plane anisotropy $\Gamma_2$ in the effective superexchange interaction between $J_\text{eff}={1\over 2}$ pseudospins, originating from the cooperative interplay between Hund's rule coupling and spin-orbit coupling of Ir $5d$ electrons, is able to lift the degeneracy and stabilize the pseudospin currents. The effective single-orbital model of $J_\text{eff}={1\over 2}$ electrons, including onsite Coulomb repulsion $U$, nearest neighbor Coulomb repulsion $V$, and the in-plane anisotropy $\Gamma_2$, is then studied. We obtain the mean-field ground states, analyze their properties, and determine the phase diagram of stoichiometric Sr$_{2}$IrO$_{4}$ in the plane spanned by $U$ and $V$ at a fixed $\Gamma_2$. We demonstrate the realization of $d$PSCO, and its competition and coexistence with antiferromagnetism. Remarkably, we find the coexistence of $d$PSCO and antiferromagnetism naturally leads to spin bond nematicity, with the spin directions of these three orders forming nontrivial chirality. Furthermore, we show that the emergence of the coexistent state and its chirality can be tuned by carrier doping.Comment: 12 pages, 10 figure

A supra-massive magnetar central engine for short GRB 130603B

We show that the peculiar early optical and in particular X-ray afterglow emission of the short duration burst GRB 130603B can be explained by continuous energy injection into the blastwave from a supra-massive magnetar central engine. The observed energetics and temporal/spectral properties of the late infrared bump (i.e., the "kilonova") are also found consistent with emission from the ejecta launched during an NS-NS merger and powered by a magnetar central engine. The isotropic-equivalent kinetic energies of both the GRB blastwave and the kilonova are about $E_{\rm k}\sim 10^{51}$ erg, consistent with being powered by a near-isotropic magnetar wind. However, this relatively small value demands that most of the initial rotational energy of the magnetar $(\sim {\rm a~ few \times 10^{52}~ erg})$ is carried away by gravitational wave radiation. Our results suggest that (i) the progenitor of GRB 130603B would be a NS-NS binary system, whose merger product would be a supra-massive neutron star that lasted for about $\sim 1000$ seconds; (ii) the equation-of-state of nuclear matter would be stiff enough to allow survival of a long-lived supra-massive neutron star, so that it is promising to detect bright electromagnetic counterparts of gravitational wave triggers without short GRB associations in the upcoming Advanced LIGO/Virgo era.Comment: Five pages including 1 Figure, to appear in ApJ

Feedback-based debugging

National Research Foundation (NRF) Singapor