The Mechanical\u27s Bull-Session 1930

https://ir.uiowa.edu/mechanicals-bull-session/1000/thumbnail.jp

Media 3: Real-time compressive sensing spectral domain optical coherence tomography

Originally published in Optics Letters on 01 January 2014 (ol-39-1-76

Strong Anisotropic Interaction Controls Unusual Sticking and Scattering of CO at Ru(0001)

Originally published in JOSA A on 01 September 2014 (josaa-31-9-2064

Media 1: Real-time 3D and 4D Fourier domain Doppler optical coherence tomography based on dual graphics processing units

Originally published in Biomedical Optics Express on 01 September 2012 (boe-3-9-2162

Media 1: Real-time dispersion-compensated image reconstruction for compressive sensing spectral domain optical coherence tomography

Originally published in JOSA A on 01 September 2014 (josaa-31-9-2064

Media 1: Real-time compressive sensing spectral domain optical coherence tomography

Originally published in Optics Letters on 01 January 2014 (ol-39-1-76

Media 1: Fiber-optic OCT sensor guided “SMART” micro-forceps for microsurgery

Originally published in Biomedical Optics Express on 01 July 2013 (boe-4-7-1045

Media 3: Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis

Originally published in Optics Letters on 01 March 2013 (ol-38-5-805

Media 1: Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis

Originally published in Optics Letters on 01 March 2013 (ol-38-5-805

MEMS-Based Handheld Fourier Domain Doppler Optical Coherence Tomography for Intraoperative Microvascular Anastomosis Imaging

<div><p>Purpose</p><p>To demonstrate the feasibility of a miniature handheld optical coherence tomography (OCT) imager for real time intraoperative vascular patency evaluation in the setting of super-microsurgical vessel anastomosis.</p><p>Methods</p><p>A novel handheld imager Fourier domain Doppler optical coherence tomography based on a 1.3-µm central wavelength swept source for extravascular imaging was developed. The imager was minimized through the adoption of a 2.4-mm diameter microelectromechanical systems (MEMS) scanning mirror, additionally a 12.7-mm diameter lens system was designed and combined with the MEMS mirror to achieve a small form factor that optimize functionality as a handheld extravascular OCT imager. To evaluate <i>in-vivo</i> applicability, super-microsurgical vessel anastomosis was performed in a mouse femoral vessel cut and repair model employing conventional interrupted suture technique as well as a novel non-suture cuff technique. Vascular anastomosis patency after clinically successful repair was evaluated using the novel handheld OCT imager.</p><p>Results</p><p>With an adjustable lateral image field of view up to 1.5 mm by 1.5 mm, high-resolution simultaneous structural and flow imaging of the blood vessels were successfully acquired for BALB/C mouse after orthotopic hind limb transplantation using a non-suture cuff technique and BALB/C mouse after femoral artery anastomosis using a suture technique. We experimentally quantify the axial and lateral resolution of the OCT to be 12.6 µm in air and 17.5 µm respectively. The OCT has a sensitivity of 84 dB and sensitivity roll-off of 5.7 dB/mm over an imaging range of 5 mm. Imaging with a frame rate of 36 Hz for an image size of 1000(lateral)×512(axial) pixels using a 50,000 A-lines per second swept source was achieved. Quantitative vessel lumen patency, lumen narrowing and thrombosis analysis were performed based on acquired structure and Doppler images.</p><p>Conclusions</p><p>A miniature handheld OCT imager that can be used for intraoperative evaluation of microvascular anastomosis was successfully demonstrated.</p></div