3,892 research outputs found

    Openness, growth and inflation

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    Is the Export-led Growth Hypothesis Valid for an Export-oriented Economy? Korean Experience

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    The export-led growth hypothesis has been examined for the Korean economy that heavily depended on international trade. We employed a textbook-style regression model and found that export expansion had an insignificant effect on economic growth. The insignificant growth effect was robust across sample periods and model specifications. We further employed an instrumental variable (IV) for export growth and found that the causal effect was strengthened but not large enough to be statistically significant. Our results thus appear to be at odds with the findings of export-led growth in the existing literature. A separate model was estimated further for growth-driven exports, but the feedback effect of GDP growth on export expansion was also found to be small and insignificant. Perhaps, the discrepancy might be due to fancy time-series techniques used in the literature that may distort causal directions erratically

    Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption

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    Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs) obtained from Vav1-deficient (Vav1−/−) and wild-type (WT) mice to differentiate into mature OCs upon stimulation with macrophage colony stimulating factor and receptor activator of nuclear kappa B ligand in vitro. Our results suggested that Vav1 deficiency promoted the differentiation of BMMCs into OCs, as indicated by the increased expression of tartrate-resistant acid phosphatase, cathepsin K, and calcitonin receptor. Therefore, Vav1 may play a negative role in OC differentiation. This hypothesis was supported by the observation of more OCs in the femurs of Vav1−/− mice than in WT mice. Furthermore, the bone status of Vav1−/− mice was analyzed in situ and the femurs of Vav1−/− mice appeared abnormal, with poor bone density and fewer number of trabeculae. In addition, Vav1-deficient OCs showed stronger adhesion to vitronectin, an αvβ3 integrin ligand important in bone resorption. Thus, Vav1 may inhibit OC differentiation and protect against bone resorption

    Modelling shoreline movement using two extreme beachface slopes

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    A new algorithm to simulate shoreline movement at general planar coastal morphology is proposed here. Two limiting slopes and a reference level are involved in this algorithm. If beach slope exceeds a certain value during numerical morphological modelling, the beach profile undergoes correction by moving some sediment volume to underwater zone. If beach slope becomes smaller than the other slope, the beach profile is corrected by moving some sediment volume to onshore zone. Final adjustment is carried out to sort out three-dimensionality. The algorithm is applied to a laboratory experiment showing tombolo generation behind a detached breakwater, and demonstrates its usefulness with reasonable accuracy

    3D culture technologies of cancer stem cells: promising ex vivo tumor models

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    Cancer stem cells have been shown to be important in tumorigenesis processes, such as tumor growth, metastasis, and recurrence. As such, many three-dimensional models have been developed to establish an ex vivo microenvironment that cancer stem cells experience under in vivo conditions. Cancer stem cells propagating in three-dimensional culture systems show physiologically related signaling pathway profiles, gene expression, cell–matrix and cell–cell interactions, and drug resistance that reflect at least some of the tumor properties seen in vivo. Herein, we discussed the presently available Cancer stem cell three-dimensional culture models that use biomaterials and engineering tools and the biological implications of these models compared to the conventional ones

    Electron−hole separation in ferroelectric oxides for efficient photovoltaic responses

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    Despite their potential to exceed the theoretical Shockley−Queisser limit, ferroelectric photovoltaics (FPVs) have performed inefficiently due to their extremely low photocurrents. Incorporating Bi₂FeCrO₆(BFCO) as the light absorber in FPVs has recently led to impressively high and record photocurrents [Nechache R, et al. (2015) Nat Photonics 9:61–67], which has revived the FPV field. However, our understanding of this remarkable phenomenon is far from satisfactory. Here, we use first-principles calculations to determine that such excellent performance mainly lies in the efficient separation of electron− hole (e-h) pairs. We show that photoexcited electrons and holes in BFCO are spatially separated on the Fe and Cr sites, respectively. This separation is much more pronounced in disordered BFCO phases, which adequately explains the observed exceptional PV responses. We further establish a design strategy to discover next-generation FPV materials. By exploring 44 additional Bi-based double-perovskite oxides, we suggest five active-layer materials that offer a combination of strong e-h separations and visible-light absorptions for FPV applications. Our work indicates that charge separation is the most important issue to be addressed for FPVs to compete with conventional devices. Keywords: ferroelectrics; double perovskites; photovoltaics; e-h separation; density functional theor

    Single-filament Composite MgB2/SUS Ribbons by Powder-In-Tube Process

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    We report the successful fabrication of single-filament composite MgB2/SUS ribbons, as an ultra-robust conductor type, employing the powder-in-tube (PIT) process, by swaging and cold rolling only. The remarkable transport critical current (Ic) of the non-sintered MgB2/SUS ribbon has observed, as an unexpected result. Transport critical currents Ic ~ 316 A at T = 4.2 K and Ic ~ 82 A at T = 20 K were observed at self-field, for the non-sintered composite MgB2/SUS ribbon. In addition, the persistent current density Jp values, that were estimated by Bean formula, were more than ~ 7  105 A/cm2 at T = 5 K, and ~ 1.2  105 A/cm2 at T = 30 K, for the sintered composite MgB2/SUS ribbon, at H = 0 G.Comment: 10 pages, 4 figure

    Calorimetric Evidence for Nodes in the Overdoped Ba(Fe0.9_{0.9}Co0.1_{0.1})2_{2}As2_{2}

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    We present low-temperature specific heat of the electron-doped Ba(Fe0.9_{0.9}Co0.1_{0.1})2_{2}As2_{2}, which does not show any indication of an upturn down to 400 mK, the lowest measuring temperature. The lack of a Schottky-like feature at low temperatures or in magnetic fields up to 9 Tesla enables us to identify enhanced low-temperature quasiparticle excitations and to study anisotropy in the linear term of the specific heat. Our results can not be explained by a single or multiple isotropic superconducting gap, but are consistent with multi-gap superconductivity with nodes on at least one Fermi surface sheet.Comment: 5 pages 4 figure

    Interface structure and strain relaxation in BaTiO3 thin films grown on GdScO3 and DyScO3 substrates with buried coherent SrRuO3 layer

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    To obtain the electrical properties of strained ferroelectric thin films, bottom electrodes with lattice constants and thermal coefficients matched to both films and substrates are needed. The interface structure, strain configuration, and strain relaxation in such bilayer systems are different from those in single layer systems. Here, we report transmission electron microscopy studies of epitaxial BaTiO3 films grown on GdScO3 and DyScO3 substrates with buried SrRuO3 layers. We found that the different strain relaxation behaviors observed in the bilayer are mainly dependent on lattice mismatch of each layer to the substrate and the thicknesses of each layer.open7
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