Mindfulness and skills-based eHealth intervention to reduce distress in cancer-affected patients in the Reduct trial: Intervention protocol of the make it training optimized.

Introduction Cancer-affected patients experience high distress due to various burdens. One way to expand psycho-oncological support is through digital interventions. This protocol describes the development and structure of a web-based psycho-oncological intervention, the Make It Training optimized. This intervention is currently evaluated in the Reduct trial, a multicenter randomized controlled trial. Methods The Make It Training optimized was developed in six steps: A patient need and demand assessment, development and acceptability analysis of a prototype, the formation of a patient advisory council, the revision of the training, implementation into a web app, and the development of a motivation and evaluation plan. Results Through a process of establishing cancer-affected patients' needs, prototype testing, and patient involvement, the Make It Training optimized was developed by a multidisciplinary team and implemented in a web app. It consists of 16 interactive self-guided modules which can be completed within 16 weeks. Discussion Intervention protocols can increase transparency and increase the likelihood of developing effective web-based interventions. This protocol describes the process and results of developing a patient-oriented intervention. Future research should focus on the further personalization of web-based psycho-oncological interventions and the potential benefits of combining multiple psychotherapeutic approaches

Digital Health Randomized Controlled Trials Among Patients with Cardiovascular Diseases: A Systematic Literature Search

A systematic literature search on the topic of digital health randomized controlled trials among patients with cardiovascular diseases was conducted as part of the application for funding of clinical trials of high relevance to patient care to the German Federal Ministry of Education and Research (BMBF). Between August and October 2022, the databases Medline/PubMed, Cochrane Library, clinicaltrials.gov, German Clinical Trials Regist and International Clinical Trials Search Portal have been searched by two experienced staff members. The search resulted into 244 research articles, of which 16 were considered relevant after title and abstract review

Development and validation of the English version of the Man-Made Disaster-Related Distress Scale (eMMDS) - an online questionnaire study

Although man-made disasters (MMD) have an increasing relevance and cause remarkable levels of psychological distress, measurement instruments assessing the consequences of MMD are still rare. Especially in indirectly affected regions, research is lacking. To fill this gap, the man-made disaster-related distress scale (MMDS; Krakowczyk et al., 2023) was developed. With its good measurement properties, the MMDS showed the potential to be used as a reliable instrument for the measurement of psychological distress associated with MMD in indirectly affected countries. Therefore, the aim of the present study is to make the MMDS available to more countries by developing and validating it for the English language (eMMDS)

Development and validation of a climate change version of the Man-Made Disaster-Related Distress Scale (MMDScc)

Although man-made disasters (MMD) have an increasing relevance and cause remarkable levels of psychological distress, measurement instruments assessing the consequences of MMD are still rare. So far, the man-made disaster-related distress scale (MMDS), developed by Krakowczyk and colleagues in 2023, showed good properties for the measurement of distress through the indirect influence of war. However, not only war, but also the climate change can be regarded as an MMD with influences on mental health. Therefore, the aim of the present study is to adapt the MMDS to climate change and validate it as an MMDS-climate change version (MMDScc)