9,694 research outputs found

    Predicting solar cycle 24 with a solar dynamo model

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    Whether the upcoming cycle 24 of solar activity will be strong or not is being hotly debated. The solar cycle is produced by a complex dynamo mechanism. We model the last few solar cycles by `feeding' observational data of the Sun's polar magnetic field into our solar dynamo model. Our results fit the observed sunspot numbers of cycles 21-23 extremely well and predict that cycle~24 will be about 35% weaker than cycle~23.Comment: 10 pages 1 table 3 figure

    The Cone-Like H-alpha Nebula in NGC 4945: A Galactic Superwind Bow Shock ?

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    We find that a non-axisymmetric bow shock model, with an appropriate choice of parameters, could fit the line splitting velocity field of the cone-like Hα\alpha nebula in NGC 4945 better than a canonical cone model. Meanwhile, the bow shock model could also reproduce the morphology of the Hα\alpha nebula. The bow shock results from the interaction of the galactic superwinds with a giant HII region. It is implied that the starburst ring or disk around the galactic nucleus should be generating strong winds, and the bright Hα\alpha knot northwest of the nucleus be suffering an anisotropic mass loss process.Comment: 14 pages, aasms4.sty, 3 figures not included (available upon request) To appear in ApJ Letters. email chy, [email protected]

    Muon Pair Production by Electron-Photon Scatterings

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    The cross section for muon pair productions by electrons scattering over photons, σMPP\sigma_{MPP}, is calculated analytically in the leading order. It is pointed out that for the center-of-mass energy range, s5mμ2s \geq 5 m^{2}_{\mu}, the cross section for σMPP\sigma_{MPP} is less than 1μ1 \mu b. The differential energy spectrum for either of the resulting muons is given for the purpose of high-energy neutrino astronomy. An implication of our result for a recent suggestion concerning the high-energy cosmic neutrino generation through this muon pair is discussed.Comment: a comment added, to appear in Phys. Rev. D, Rapid Communicatio

    A High-Throughput Method for Illumina RNA-Seq Library Preparation.

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    With the introduction of cost effective, rapid, and superior quality next generation sequencing techniques, gene expression analysis has become viable for labs conducting small projects as well as large-scale gene expression analysis experiments. However, the available protocols for construction of RNA-sequencing (RNA-Seq) libraries are expensive and/or difficult to scale for high-throughput applications. Also, most protocols require isolated total RNA as a starting point. We provide a cost-effective RNA-Seq library synthesis protocol that is fast, starts with tissue, and is high-throughput from tissue to synthesized library. We have also designed and report a set of 96 unique barcodes for library adapters that are amenable to high-throughput sequencing by a large combination of multiplexing strategies. Our developed protocol has more power to detect differentially expressed genes when compared to the standard Illumina protocol, probably owing to less technical variation amongst replicates. We also address the problem of gene-length biases affecting differential gene expression calls and demonstrate that such biases can be efficiently minimized during mRNA isolation for library preparation

    Constraints on holographic dark energy models using the differential ages of passively evolving galaxies

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    Using the absolute ages of passively evolving galaxies observed at different redshifts, one can obtain the differential ages, the derivative of redshift zz with respect to the cosmic time tt (i.e. dz/dt{\rm d} z/{\rm d}t). Thus, the Hubble parameter H(z)H(z) can be measured through the relation H(z)=(dz/dt)/(1+z)H(z)=-({\rm d} z/{\rm d}t)/(1+z). By comparing the measured Hubble parameter at different redshifts with the theoretical one containing free cosmological parameters, one can constrain current cosmological models. In this paper, we use this method to present the constraint on a spatially flat Friedman-Robert-Walker Universe with a matter component and a holographic dark energy component, in which the parameter cc plays a significant role in this dark energy model. Firstly we consider three fixed values of cc=0.6, 1.0 and 1.4 in the fitting of data. If we set cc free, the best fitting values are c=0.26c=0.26, Ωm0=0.16\Omega_{\rm m0}=0.16, h=0.9998h=0.9998. It is shown that the holographic dark energy behaves like a quintom-type at the 1σ1\sigma level. This result is consistent with some other independent cosmological constrains, which imply that c<1.0c<1.0 is favored. We also test the results derived from the differential ages using another independent method based on the lookback time to galaxy clusters and the age of the universe. It shows that our results are reliable.Comment: 18 pages including 7 figures and 1 tables. Final version for publication in Modern Physics Letters A (MPLA)[minor revision to match the appear version

    Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas.

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    A novel glucose transporter, the sodium glucose cotransporter 2 (SGLT2), has been demonstrated to contribute to the demand for glucose by pancreatic and prostate tumors, and its functional activity has been imaged using a SGLT specific PET imaging probe, α-methyl-4-[F-18]fluoro-4-deoxy-D-glucopyaranoside (Me-4FDG). In this study, Me-4FDG PET was extended to evaluate patients with high-grade astrocytic tumors. Me-4FDG PET scans were performed in four patients diagnosed with WHO Grade III or IV astrocytomas and control subjects, and compared with 2-deoxy-2-[F-18]fluoro-D-glucose (2-FDG) PET and magnetic resonance imaging (MRI) of the same subjects. Immunocytochemistry was carried out on Grade IV astrocytomas to determine the cellular location of SGLT proteins within the tumors. Me-4FDG retention was pronounced in astrocytomas in dramatic contrast to the lack of uptake into the normal brain, resulting in a high signal-to-noise ratio. Macroscopically, the distribution of Me-4FDG within the tumors overlapped with that of 2-FDG uptake and tumor definition using contrast-enhanced MRI images. Microscopically, the SGLT2 protein was found to be expressed in neoplastic glioblastoma cells and endothelial cells of the proliferating microvasculature. This preliminary study shows that Me-4FDG is a highly sensitive probe for visualization of high-grade astrocytomas by PET. The distribution of Me-4FDG within tumors overlapped that for 2-FDG, but the absence of background brain Me-4FDG resulted in superior imaging sensitivity. Furthermore, the presence of SGLT2 protein in astrocytoma cells and the proliferating microvasculature may offer a novel therapy using the SGLT2 inhibitors already approved by the FDA to treat type 2 diabetes mellitus

    Long-range frustration in T=0 first-step replica-symmetry-broken solutions of finite-connectivity spin glasses

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    In a finite-connectivity spin-glass at the zero-temperature limit, long-range correlations exist among the unfrozen vertices (whose spin values being non-fixed). Such long-range frustrations are partially removed through the first-step replica-symmetry-broken (1RSB) cavity theory, but residual long-range frustrations may still persist in this mean-field solution. By way of population dynamics, here we perform a perturbation-percolation analysis to calculate the magnitude of long-range frustrations in the 1RSB solution of a given spin-glass system. We study two well-studied model systems, the minimal vertex-cover problem and the maximal 2-satisfiability problem. This work points to a possible way of improving the zero-temperature 1RSB mean-field theory of spin-glasses.Comment: 5 pages, two figures. To be published in JSTA

    Quantum discord dynamical behaviors due to initial system-cavity correlations

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    We analyze the roles of initial correlations between the two-qubit system and a dissipative cavity on quantum discord dynamics of two qubits. Considering two initial system-cavity states, we show that the initial system-cavity correlations not only can initially increase the two-qubit quantum discord but also would lead to a larger long-time quantum discord asymptotic value. Moreover, quantum discord due to initial correlations is more robust than the case of the initial factorized state. Finally, we show the initial correlations' importance for dynamics behaviors of mutual information and classical correlation

    Time-variant TEC estimation with fully polarimetric GEO-SAR data

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    A time-variant total electron content (TEC) estimation method with fully polarimetric geosynchronous synthetic aperture radar (GEO-SAR) data is proposed based on inner aperture Faraday rotation angle estimation and an accurate TEC inversion model. With a long integration time and sensitivity to ionosphere effects, the fully polarimetric GEO-SAR data are utilised for estimation with high accuracy for both the time-variant TEC and the time interval. Superiority of the proposed method over conventional ionospheric sounding methods is verified by simulation results
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