High-Throughput Screening of Metal–Organic Frameworks for Hydrogen Storage at Cryogenic Temperature

Metal–organic frameworks (MOFs) have attracted significant interest as a class of adsorbent materials for gas storage applications, including hydrogen storage for fuel cell vehicles. Here, we evaluated 137 953 hypothetical MOFs for hydrogen storage at cryogenic conditions (77 K) by determining the deliverable storage capacity between 100 and 2 bar, using grand canonical Monte Carlo simulations. The highest predicted volumetric capacity for a structure in this study is 50 g/L, and the highest gravimetric capacity is almost 25 wt %. We find that the optimal void fraction is 0.9 and the optimal pore diameter is 12–15 Å. MOFs with larger pores have significant regions in the center of the pore with low hydrogen density, which lowers the storage efficiency. We give examples of MOFs with very large pores in which the hydrogen capacity can potentially be increased using catenation or functional groups to reduce the pore size and increase the surface area per volume. We also introduce a screening parameter, the binding fraction, which is the fraction of the unit cell volume within a given distance of the framework. This metric is inexpensive to compute and is a strong predictor of hydrogen storage capacity. This simple parameter could be used to quickly screen even larger numbers of MOFs for gas adsorption capacity to identify the most promising candidates for more detailed study

Transition Metal Induced the Contraction of Tungsten Carbide Lattice as Superior Hydrogen Evolution Reaction Catalyst

Tungsten carbide (WC) materials have exhibited platinum-like catalytic behavior in many fields, whereas the adsorption of pure tungsten carbide for H is too strong and demonstrates low activity for hydrogen evolution reaction (HER). Herein, we successfully introduced transition metal into WC lattice and optimized the electron structure around Fermi level (<i>E</i>_F) of WC via facile annealing CoW-based metal–organic framework precursors. X-ray diffraction, X-ray photoelectron spectroscopy, and X-ray absorption fine structure verified the incorporation of Co and the contraction of WC lattice. Density functional theory calculations indicated that the doping of Co into WC significantly increases the state density of WC at <i>E</i>_F derived from the delocalization of Co charge, resulting in the moderate H₂O binding energy and weakened H adsorption. As expected, the optimal Co-doping WC (Co/W molar ratio = 3) efficiently catalyzed HER with a low onset potential (31 mV) and a current density of 10 mA cm^–2 at a low overpotential of 98 mV in 1.0 M KOH media, which was superior to that of WC/CN and Co/CN. Similarly, Ni and Fe could also modulate the electronic structure of WC and improve the HER activity

Table_3_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.docx

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Image_4_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.jpeg

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Table_4_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.docx

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Table_1_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.docx

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Image_3_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.jpeg

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Table_2_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.docx

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Table_6_The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.docx

BackgroundCurrently, the optimal adjuvant regional nodal irradiation (RNI) volume for breast cancer (BC) remained controversial. We aimed to define the optimal RNI treatment volume for BC by using a comprehensive network meta-analysis (NMA) of published studies.Materials and methodsPubMed, Embase, Medline, and Cochrane Central Register of Controlled Trials were searched from database inception to 30 May 2022. Studies assessing different adjuvant RNI volumes for BC were eligible for inclusion. The primary outcome was overall survival (OS), and secondary outcome was disease-free survival (DFS) and distant-metastasis-free survival (DMFS).ResultsA total of 29,640 BC patients from twenty studies were included. The pooled hazard ratio demonstrated that internal mammary node irradiation (IMNI) in BC patients significantly improved OS giving HR (hazard ratio) of 0.87 (95%CI: 0.83–0.91, pConclusionsOur pooled results demonstrated that RNI with IMNI yielded a significant survival advantage for BC patients. NMA showed that CW/WB+RNI with IMNI was the optimal radiation volume for BC patients.</p

Reliable and Efficient Content Sharing for 5G-Enabled Vehicular Networks

Conditional privacy preservation and message authentication serve as the primary research issues in terms of security in vehicular networks. With the arrival of 5G era, the downloading speed of network services and the message transmission speed have significantly improved. Consequently, the content exchanged by users in vehicular networks is not limited to traffic information, and vehicles moving at high speeds can share a wide variety of contents. However, sharing content reliably and efficiently remains challenging owing to the fast-moving character of vehicles. To solve this problem, we propose a reliable and efficient content sharing scheme in 5G-enabled vehicular networks. The vehicles with content downloading requests quickly filter the adjacent vehicles to choose capable and suitable proxy vehicles and request them for content services. Thus, the purpose of obtaining a good hit ratio, saving network traffic, reducing time delay, and easing congestion during peak hours can be achieved. The security analysis indicates that the proposed scheme meets the security requirements of vehicular networks. Our cryptographic operations are based on the elliptic curve, and finally, the proposed scheme also displays favorable performance compared to other related schemes