39 research outputs found

    Carbon Dioxide Emission Peak and Green Innovation-Driven — Research of Escaping Middle Income Trap for China

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    This study explains and demonstrates whether China has the capability to avoid the Middle Income Trap. The 19th National Congress of CPC report points out: by 2035, China will become an international leader in innovation. At present, China is in the juncture of changing the mode of development, optimizing the economic structure and transforming the growth momentum. The juncture means that it is possible to be stagnation or retrogression of national economy as the national ability of innovation is insufficient, then sticking in the middle-income trap (MIC) for a long time. In this paper, we used the TFP to prove that the input-output ratio of different regions of China, with the per capita GDP and carbon emissions are fitting again, dividing China into optimized zones and non-optimized zones. It can be seen from the results that the optimized zones have achieved the peak of carbon emission and had relative advantages in green innovation. However, if China wants to achieve her overall carbon emissions and get out of the middle income trap, she must optimize the development zones to spillover technologies and talents

    Estimation of Soil Moisture Index Using Multi-Temporal Sentinel-1 Images over Poyang Lake Ungauged Zone

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    The C-band radar instruments onboard the two-satellite GMES Sentinel-1 constellation provide global measurements with short revisit time (about six days) and medium spatial resolution (5 × 20 m), which are appropriate for watershed scale hydrological applications. This paper aims to explore the potential of Sentinel-1 for estimating surface soil moisture using a multi-temporal approach. To this end, a linear mixed effects (LME) model was developed over Poyang Lake ungauged zone, using time series Sentinel 1A and 1B images and soil moisture ground measurements from 15 automatic observation sites. The model assumed a linear relationship that varied with both time and space between soil moisture and backscattering coefficient (SM- σ 0 ). Results showed that three LME models developed with different polarized σ 0 images all meet the European Space Agency (ESA) accuracy requirement for GMES soil moisture product (≤5% in volume), with the vertical transmit and vertical receive (VV) polarized model achieving the best performance. However, the SM- σ 0 relationship was found to depend strongly on space, making it difficult to predict absolute soil moisture for each grid. Therefore, a relative soil moisture index was then proposed to correct for site effect. When compared with those of the linear fixed effects model, the soil moisture indices predicted by the LME model captured the temporal dynamics of measured soil moisture better, with the overall R2 and cross-validated R2 being 0.68 and 0.64, respectively. These results indicate that the LME model can be effectively applied to estimate soil moisture from multi-temporal Sentinel-1 images, which is useful for monitoring flood and drought disasters, and for improving stream flow prediction over ungauged zones

    Immunomodulatory and Antioxidant Effects of Polysaccharides from the Parasitic Fungus Cordyceps kyushuensis

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    The ascomycete Cordyceps genus has been used as valued traditional Chinese medicine. Cordyceps kyushuensis is a unique species of Cordyceps, which parasitizes on the larvae of Clanis bilineata Walker, and its major component cordycepin and aqueous extract are known to have many pharmacological effects. However, the physiological function of water-soluble polysaccharides has not been explored in detail. In this study, to resolve these doubts, we extracted and separated Cordyceps-derived polysaccharides and then evaluated the immunomodulatory and antioxidant activities. Four polysaccharide fractions were purified from Cordyceps-cultured stroma by DEAE-cellulose 23 and Sephadex G-150 column chromatography. Basic structural information was elucidated on the basis of physicochemical property and spectroscopic evidences. The antioxidant activities were evaluated by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical method and protective effect of DNA damage. The qualified immunologic activities were also determined in vivo and in vitro. The polysaccharides could stimulate the proliferation of mouse splenocytes whether concanavalin A (ConA) and lipopolysaccharide (LPS) existed or not, strengthen peritoneal macrophages to devour neutral red, and increase the content of interleukin-2 (IL-2) and tumor necrosis factor-alpha (TNF-α) in serum. The research provides the corresponding evidence for Cordyceps polysaccharides as a potential candidate for functional foods and therapeutic agents

    A Prediction Model for ROS1-Rearranged Lung Adenocarcinomas based on Histologic Features.

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    AIMS:To identify the clinical and histological characteristics of ROS1-rearranged non-small-cell lung carcinomas (NSCLCs) and build a prediction model to prescreen suitable patients for molecular testing. METHODS AND RESULTS:We identified 27 cases of ROS1-rearranged lung adenocarcinomas in 1165 patients with NSCLCs confirmed by real-time PCR and FISH and performed univariate and multivariate analyses to identify predictive factors associated with ROS1 rearrangement and finally developed prediction model. Detected with ROS1 immunochemistry, 59 cases of 1165 patients had a certain degree of ROS1 expression. Among these cases, 19 cases (68%, 19/28) with 3+ and 8 cases (47%, 8/17) with 2+ staining were ROS1 rearrangement verified by real-time PCR and FISH. In the resected group, the acinar-predominant growth pattern was the most commonly observed (57%, 8/14), while in the biopsy group, solid patterns were the most frequently observed (78%, 7/13). Based on multiple logistic regression analysis, we determined that female sex, cribriform structure and the presence of psammoma body were the three most powerful indicators of ROS1 rearrangement, and we have developed a predictive model for the presence of ROS1 rearrangements in lung adenocarcinomas. CONCLUSIONS:Female, cribriform structure and presence of psammoma body were the three most powerful indicator of ROS1 rearrangement status, and predictive formula was helpful in screening ROS1-rearranged NSCLC, especially for ROS1 immunochemistry equivocal cases
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