Second-Harmonic Generation and Spectrum Modulation by Active Nonlinear Metamaterial

The nonlinear properties of a metamaterial sample composed of double-layer metallic patterns and voltage controllable diodes are experimentally investigated. Second harmonics and spectrum modulations are clearly observed in a wide band of microwave frequencies, showing that this kind of metamaterial is not only tunable by low DC bias voltage, but also behaves strong nonlinear property under a small power incidence. These properties are difficult to be found in normal, naturally occurring materials.Comment: 14 pages, 4 figure

Insight into Bioactivity of In‐situ Trapped Enzyme‐Covalent‐Organic Frameworks

Selecting a suitable support material for enzyme immobilization with excellent biocatalytic activity and stability is a critical aspect in the development of functional biosystems. The highly stable and metal‐free properties of covalent‐organic frameworks (COFs) make them ideal supports for enzyme immobilization. Herein, we constructed three kinds of COFs via a biofriendly and one‐pot synthetic strategy at room temperature in aqueous solution. Among the three developed COFs (COF‐LZU1, RT‐COF‐1 and ACOF‐1), the horseradish peroxidase (HRP)‐incorporated COF‐LZU1 is found to retain the highest activity. Structural analysis reveals that a weakest interaction between the hydrated enzyme and COF‐LZU1, an easiest accessibility by the COF‐LZU1 to the substrate, as well as an optimal conformation of enzyme together promote the bioactivity of HRP‐COF‐LZU1. Furthermore, the COF‐LZU1 is revealed to be a versatile nanoplatform for encapsulating multiple enzymes. The COF‐LZU1 also offers superior protection for the immobilized enzymes under harsh conditions and during recycling. The comprehensive understanding of interfacial interactions of COF host and enzyme guest, the substrate diffusion, as well as the enzyme conformation alteration within COF matrices represents an opportunity to design the ideal biocatalysts and opens a broad range of applications of these nanosystems

Fault severity assessment of rolling bearings method based on improved VMD and LSTM

In order to solve the problem of selection of appropriate wavelet basis function and clearly show the physical meaning of Empirical Mode Decomposition (EMD), an improved Variational Mode Decomposition (VMD) method with Long Short-Term Memory (LSTM) neural network is proposed. With the Cuckoo Search (CS) algorithm, the central frequency updating rules of VMD are optimized. And the low efficiency and local optimum problem is avoided. Meanwhile the decomposition layer number is found by the instantaneous frequency theory. For improving the prediction accuracy in traditional regression prediction methods, a LSTM neural network is designed for regression prediction of time sequence characteristics. The proposed method is implemented on actual bearings data which is derived from the bearing laboratory of Case West Reserve University in the United States and the University of Cincinnati Bearing Data Center. The experimental results showed that the improved VMD method was more robust and more accurate than the other traditional methods. And it has some practical value for real application and guiding significance for theory

Explanatory Diagnosis of an Ontology Stream via Reasoning About Actions

International audienceExplanatory diagnosis of an ontology stream aims to explain the changes hidden in the ontology stream by a sequence of actions. In this paper, we present a framework for explanatory diagnosis of an ontology stream, which allows the actions to be uncertain. In order to capture the semantics of actions, we introduce a new update operator and effect-guided bold-repair. By combining these operators with a query mechanism of description logics EL ++ supporting inconsistency-tolerant semantics, we present a formal definition for the explanatory diagnosis problem of ontology streams

Asymmetric Phenotypes of Sterile Hybrid Males From Reciprocal Crosses Between Species of the Anopheles gambiae Complex

Haldane’s rule of speciation states that sterility or inviability affects the heterogametic sex of inter-species hybrids. Darwin’s corollary to Haldane’s rule implies that there are asymmetric phenotypes in inter-species hybrids from reciprocal crosses. Studying the phenotypes of F1 hybrids among closely related species of malaria mosquitoes can assist researchers in identifying the genetic factors and molecular mechanisms of speciation. To characterize phenotypes of sterile hybrid males in the Anopheles gambiae complex, we performed crosses between laboratory strains of An. merus and either An. gambiae or An. coluzzii. The reproductive tracts had normal external morphology in hybrid males from crosses between female An. merus and male An. gambiae or An. coluzzii. Despite being sterile, these males could copulate with females for a normal period of time and could transfer a mating plug to induce female oviposition and monogamy. In contrast, the entire reproductive tracts in hybrid males from crosses between female An. gambiae or An. coluzzii and male An. merus were severely underdeveloped. These males had atrophic testes and reduced somatic organs of the reproductive system including male accessary glands and ejaculatory duct. In addition, hybrid males with underdeveloped reproductive tracts displayed a shorter copulation time with females and failed to induce female oviposition and monogamy due to their inability to form and transfer a plug to females during mating. The asymmetry of the phenotypes associated with hybrid male sterility suggests that different genetic factors and molecular mechanisms are responsible for reproductive isolation in reciprocal crosses among species of the An. gambiae complex

Quantitative interocular suppression in children with intermittent exotropia

PurposeWe have demonstrated that the depth of unbalanced interocular suppression can be quantified by balancing the interocular luminance differences required when both eyes are viewing simultaneously. In this study, we aimed to investigate the applicability of this method in children with intermittent exotropia (IXT), offering a quantitative assessment of interocular suppression in individuals with binocular imbalance. Additionally, we evaluated its association with the clinical characteristics of IXT.MethodsInterocular suppression in IXT was quantitatively measured using a polarizer and neutral-density (ND) filters. The density of the ND filter was adjusted incrementally from 0.3ND to 3ND, with a step size of 0.3ND (a total of 10 levels). Our prospective study involved 46 patients with IXT (mean age: 10.12 ± 4.89 years; mean ± SD) and 24 normal observers (mean age: 7.88 ± 1.83 years).ResultsThe suppression test exhibited good test–retest reliability, supported by statistical analysis. We observed more pronounced interocular suppression in individuals with IXT compared to controls. Notably, the magnitude of suppression during distant and near viewing significantly differed in IXT (1.55 ± 0.93 vs. 0.57 ± 0.64; Z = 4.764, p < 0.001). Furthermore, we identified a positive correlation between interocular suppression and data obtained from the Worth-4-Dot test. Additionally, interocular suppression showed a significant association with distance control scores.ConclusionOur novel test offers a convenient and reliable means to quantify interocular suppression in patients with IXT. The quantitative assessment of interocular suppression provides a sensitive tool to evaluate the clinical characteristics of IXT

Lithospheric electrical structure across the Bangong-Nujiang Suture in northern tibet revealed by magnetotelluric

Competing hypotheses have been proposed to explain the subduction polarity of the Bangong-Nujiang Tethyan Ocean and the formation of the high-conductivity anomaly beneath the Qiangtang terrane. However, the lithospheric architecture of the northern Tibetan Plateau is still poorly understood due to inhospitable environments and topography. Therefore, in the winter of 2021, a 440 km long, SN-trending broadband magnetotelluric (MT) profile was recorded in northern Tibet to detect its regional lithospheric structure. The nonlinear conjugate gradients algorithm is conducted to invert the individual TM mode data. A reliable 2D electrical model was obtained by ablation processing and analysis of broadband magnetotelluric data to test the lithospheric electrical structure and dynamics between the northern Lhasa and Qiangtang terranes. The inversion results reveal the lithospheric structure at a depth of 100 km in northern Tibet, which synthesizes geological, geochemical and deep seismic reflection evidence and firmly identifies that the trace of the south-dipping conductor mainly resulted from the southward subduction of the Bangong-Nujiang Tethyan Ocean under the Lhasa terrane and the trace of the north-dipping conductor likely due to the northward subduction of the Bangong-Nujiang Tethyan Ocean under the Qiangtang terrane. In addition, the magnetotelluric profile also images a high-conductivity lithospheric-scale anticline beneath the central Qiangtang terrane, which may correspond to the upwelling of postcollisional magmatism triggered by northward subduction of the Bangong-Nujiang Tethyan Ocean under the Qiangtang terrane, aqueous fluid and/or partial melting