112 research outputs found

    Implications of salt tectonics on hydrocarbon ascent in the Eastern Persian gulf: insights into the formation mechanism of salt diapirs, gas chimneys, and their sedimentary interactions

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    Gas chimneys, salt domes, and faults are vital to the movement of hydrocarbons within geological systems. Accurate identification of these geological features is crucial to modeling hydrocarbon resources. This study explores the processes that have shaped the eastern Persian Gulf, focusing on salt diapir characteristics, origin, and fluid migration. Plate collisions between the Indian, Eurasian, and Arabian Plates have considerably impacted salt tectonics, developing key features such as the Hormuz salt, Qatar-South Fars Arch, and Zagros and Oman orogenic structures. Salt-related features were discerned through two-dimensional seismic data and drilling records, salt movement sequences were reconstructed, and fluid expulsion patterns were delineated using attribute preferences. The results of this study revealed that fractured substrates influenced by regional tectonic forces contribute to the creation of salt diapirs, which serve as conduits for guided fluid transport. Moreover, these results showed that gravity driven downbuilding mainly controls salt flow, while the circular arrangement of salt structures results from regional stress and interactions between different salt sources. Distinct stress-induced basement incisions compounded by the hindrance of initial salt movement by the Qatar Arch further contribute to the complex salt structure geometry. Crucially, the uplift of the Qatar Arch and stresses from the Oman and Zagros orogenies profoundly affect the salt structure geometry and depositional patterns across diverse regions, resulting in circular salt structures and gas chimneys. This study offers valuable perspectives for oil and gas exploration and provides a comprehensive understanding of the regional dynamics governing salt tectonics and hydrocarbon ascent in the eastern Persian Gulf

    A novel approach for denoising electrocardiogram signals to detect cardiovascular diseases using an efficient hybrid scheme

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    BackgroundElectrocardiogram (ECG) signals are inevitably contaminated with various kinds of noises during acquisition and transmission. The presence of noises may produce the inappropriate information on cardiac health, thereby preventing specialists from making correct analysis.MethodsIn this paper, an efficient strategy is proposed to denoise ECG signals, which employs a time-frequency framework based on S-transform (ST) and combines bi-dimensional empirical mode decomposition (BEMD) and non-local means (NLM). In the method, the ST maps an ECG signal into a subspace in the time frequency domain, then the BEMD decomposes the ST-based time-frequency representation (TFR) into a series of sub-TFRs at different scales, finally the NLM removes noise and restores ECG signal characteristics based on structural self-similarity.ResultsThe proposed method is validated using numerous ECG signals from the MIT-BIH arrhythmia database, and several different types of noises with varying signal-to-noise (SNR) are taken into account. The experimental results show that the proposed technique is superior to the existing wavelet based approach and NLM filtering, with the higher SNR and structure similarity index measure (SSIM), the lower root mean squared error (RMSE) and percent root mean square difference (PRD).ConclusionsThe proposed method not only significantly suppresses the noise presented in ECG signals, but also preserves the characteristics of ECG signals better, thus, it is more suitable for ECG signals processing

    Influence of sedimentary processes and fault tectonics on the evolution of submarine canyons in the East Andaman Basin: insights from high-resolution seismic data analysis

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    The Andaman Sea Basin, a well-known back-arc spreading centre and a mature petroliferous basin, presents a unique and complex scenario for understanding the interplay of sedimentary processes and fault tectonics on seafloor geomorphology evolution, particularly in the eastern shelf region. This study, using high-resolution 3D seismic data and published exploratory well-seismic interpretation results, aims to establish a comprehensive stratigraphic framework for the Tanintharyi region, spanning the Lower Miocene, Middle Miocene, Upper Miocene, Pliocene, and Quaternary. A submarine canyon system was identified and investigated along the Tanintharyi continental slope within the East Andaman Basin, comprising thirteen slope-confined canyons arranged predominantly in an east-west vertical slope orientation. By analysing seismic reflection features, five distinct seismic facies have been identified, including basal lag (BL), slump and debris-flow deposits (SDFDs), canyon confined sheets (CCSs), laterally inclined packages (LIPs), and channel-levees (CLs). The evolution of this canyon system, a vital focus of this study, can be categorised into three phases based on the morphology and sedimentary structures observed: canyon initiation, canyon extension, and erosion-sedimentation. The findings of this study highlight the critical controlling role of faults in canyon evolution, with the intensity of fault activity displaying a negative correlation with canyon size, indicating the direct impact of faults on geomorphological changes. In addition, the geomorphological changes induced by fault activity have resulted in changes in sediment supply, dispersal, and sedimentation rates, thus significantly impacting the spatial distribution and dimensions of slope-confined canyons within the East Andaman Basin, with far-reaching implications

    Tectonic influence on the evolutionary dynamics of deep-water channel systems along the active accretionary prism margin in the Rakhine Basin, Myanmar: a high-resolution 3d seismic analysis

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    This study reveals the morphological transformations of a deep-water channel system within the Rakhine Basin in the northeastern Bay of Bengal through a comprehensive analysis of high resolution 3D seismic data integrated with drilling logs. Employing the “source-channel-sink” paradigm, this investigation examined the impact of various factors, including tectonic transformations, sediment influx, slope dynamics, climatic changes, and relative sea-level fluctuations, on the evolutionary trajectory of these channel systems. Applying precise time slicing techniques integrating root-mean-square amplitude attributes, coherent amplitude attributes, and horizontal amplitudes on seismic profiles, this investigation recognized three distinct stages in the evolution of channel-levee complexes (CLCs): the Middle Miocene erosional deep-water channel-levee complex (CLC-1), the Pliocene erosional-depositional deep-water channel-levee complex (CLC-2), and the Pleistocene depositional deep-water channel-levee complex (CLC-3). Comparative analysis revealed that the CLC-3 exhibits unique characteristics, including shallower channel depth (D), wider channel width (WC), extensive U-shaped cross sectional area (S), broader natural levee width (WL) and height (H), and the highest tortuosity coefficient (LC/LS) when contrasted with the other two CLCs. Furthermore, this study substantiated how tectonic processes, primarily the collision between the Indo-Eurasian plates, resulting in the Himalayan and Indo-Burma Range orogenies, have shaped the region's geological and climatic framework, thereby influencing monsoon circulation and precipitation patterns, which in turn augmented detrital material influx into the basin. Moreover, this tectonic collision has led to gradual changes in the slope gradient of the Rakhine Basin and its deep-water areas, impacting internal flow velocities and channel curvature, thus governing deep-water channel systems' development and spatial distribution. Also, episodic sea level fluctuations were identified as significant contributors to sediment transport from shelves to deep-water regions and sediment deposit reworking. Overall, this study underscores the role of tectonic changes after the Eocene in driving the evolutionary dynamics of the deep-water channel system within the Rakhine Basin, Myanmar

    Unravelling cenozoic carbonate platform fluid expulsion: deciphering pockmark morphologies and genesis in the Tanintharyi shelf of the Andaman Sea as promising hydrocarbon reservoirs

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    Pockmarks, intriguing seafloor geological and geomorphological features, are commonly observed in marginal basins with hydrocarbon potential. As a Cenozoic marginal sea, the Andaman Sea is known for its significant petroleum reserves, and exploring its back-arc continental margin has revealed favourable conditions for petroleum occurrences. This study focuses on the Tanintharyi passive continental margin in the Andaman Sea, employing extensive stratigraphic and morphological analyses based on 2D and 3D seismic data interpretation techniques. Specifically, sub seafloor characteristics of the Tanintharyi shelf region were investigated, focusing on comprehensively understanding pockmark morphologies, including their generation, evolution, migration, preservation, and the complete process leading to seabed leakage. This study revealed the potential of the Oligocene/Early Miocene carbonate platform in the Tanintharyi shelf region as a significant hydrocarbon reservoir for the upwelling buoyant fluids from the deep East Andaman Basin. Besides reservoir function, this carbonate platform serves as a passageway for the migration of fluids from the deep-sea area to the shallow-sea area, thereby playing a pivotal role in supporting fluid expulsion mechanisms in shaping a pockmark train adjacent to truncated sedimentary formations surrounding a geomorphological high on the contemporary seafloor. Additionally, the study examines the influence of changes in sedimentary facies and the tectonic setting of the Andaman Sea on pockmark evolutions, with a specific emphasis on the role of the uppermost shallow marine shale beds in developing sub-seafloor overpressure systems due to their impermeable seal rock properties. The article presents substantial evidence for the initiation of pockmark fields during the Middle Miocene period, followed by their transformation into pockmark trains on the present-day seafloor, attributed to the triggering effect of sub-seafloor overpressure systems due to changes in sedimentary dynamics in the Andaman Sea

    GlyT1 inhibition by ALX-5407 attenuates allograft rejection through suppression of Th1 cell differentiation

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    ObjectiveTransplant rejection driven by Th1 cell-mediated immune responses remains a critical challenge. This study aimed to investigate the role of glycine transporter 1 (GlyT1/SLC6A9) in Th1 differentiation and evaluate the therapeutic potential of its inhibitor, ALX-5407, in attenuating allograft rejection.MethodsRNA sequencing, flow cytometry, and qRT-PCR were employed to analyze GlyT1 expression in Th1-polarized CD4+T cells. ALX-5407 (0.5–500 nM) was tested in vitro under Th1-polarizing conditions. A murine skin allograft model (BALB/c to C57BL/6) was established to assess graft survival and immune responses. Combination therapy with rapamycin and ALX-5407 was evaluated through histopathology, immunofluorescence, and splenocyte profiling. Mechanistic insights were derived from RNA-seq, KEGG/GO enrichment, and Western blotting.ResultsGlyT1 expression was significantly upregulated in Th1 cells and rejection cohorts. ALX-5407 suppressed Th1 differentiation, reducing IFN-γ+CD4+T cells proportions (p < 0.05) and activation markers (CD25, CD69), while inducing apoptosis via caspase-3 activation and BCL-2 downregulation. Although ALX-5407 monotherapy failed to prolong graft survival, combination with rapamycin synergistically enhanced efficacy (p = 0.018), reduced inflammatory infiltration, and attenuated splenic Th1 polarization. Mechanistically, ALX-5407 inhibited MAPK signaling but activated the PI3K-AKT-mTOR pathway, which rapamycin counteracted to amplify suppression.ConclusionsGlyT1 serves as a metabolic checkpoint in Th1 differentiation, and its inhibition by ALX-5407 attenuates allograft rejection through dual suppression of Th1 function and apoptosis induction. Synergy with rapamycin highlights a novel combinatorial strategy to mitigate rejection with reduced toxicity. These findings position GlyT1 targeting as a promising approach for clinical translation in transplantation immunotherapy

    Global existence and stability results for a nonlinear Timoshenko system of thermoelasticity of type III with delay

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    Abstract In this paper, we consider a nonlinear thermoelastic system of Timoshenko type with delay. It is known that an arbitrarily small delay may be the source of instability. The delay term works on the second equation which describes the motion of a rotation angle. We establish the well-posedness and the stability of the system for the cases of equal and nonequal speeds of wave propagation. Our results show that the damping effect is strong enough to uniformly stabilize the system even in the presence of time delay under suitable conditions by using perturbed energy functional technique and improve the related results

    Blow-up and global existence for solution of quasilinear viscoelastic wave equation with strong damping and source term

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    Abstract In this paper we consider a quasilinear viscoelastic wave equation with initial-boundary conditions, strong damping and source term. Under suitable assumptions on the initial data and the relaxation function, we establish a blow-up result of a solution for negative initial energy and some positive initial energy if the influence of the source term is greater than the dissipation. We show that the solution exists globally for any initial data if the influence of dissipation is greater than the source term

    Analysis of contact resistance between fitting terminals

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    Abstract In order to reduce the influence of the through-current heating between hardware terminal and the electrical equipment terminal on the performance of the hardware, this paper studies and analyzes the composition of the contact resistance of the hardware and the factors that affect the resistance value, and proposes a method to reduce the contact resistance. Under the condition that the current is constant, it can reduce the heat between the terminal blocks and provide a reference for the subsequent design of the metal terminal block.</jats:p

    Regionalization in the Yangtze River Delta, China, from the perspective of inter-city daily mobility

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    Regionalization in the Yangtze River Delta, China, from the perspective of inter-city daily mobility. Regional Studies. This paper applies a community detection algorithm to the Yangtze River Delta's (YRD) daily inter-city mobility network to produce an interaction-based regionalization, and then explores the processes underlying this regional (re-) production by comparing it with attribute-based regionalization. The results show that political boundaries and historical patterns of socio-economic integration are strikingly visible, and the effects of overlapping physical, economic, cultural and administrative spaces on regional integration are apparent. The authors conclude that both notions of 'territory' and 'network' come together as the YRD region is spatially configured, while 'regional path dependence' also seems to be relevant for understanding its relational formation
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