162 research outputs found

    Stochastic partial differential equations driven by space-time fractional noises

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    International audienceIn this paper, we study a class of stochastic partial differential equations (SPDEs) driven by space-time fractional noises. Our method consists in studying first the nonlocal SPDEs and showing then the convergence of the family of these equations and the limit gives the solution to the SPDE

    Why and when do emotionally intelligent employees perform safely? The roles of thriving at work and career adaptability

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    Based on the socially embedded model of thriving, the present study examined a moderated mediation framework, which involves the mediating role of employee thriving and the moderating role of career adaptability in the relationship between emotional intelligence (EI) and safety performance. A two-wave survey was administered among full-time commercial pilots working for airlines (N = 131). Our results showed that EI had a positive influence on employee thriving, which in turn positively affected safety performance. In addition, the results further revealed that the positive effect of EI on safety performance was stronger among pilots with a higher level of career adaptability. These findings have important implications for theoretical developments on EI, thriving, and performance in a safety context, and they also provide practical insights on how to enhance workplace safety

    A case report of multicentric reticulohistiocytosis with atypical cutaneous presentation

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    Multicentric reticulohistiocytosis (MRH) is a rare systemic disorder characterized by histiocytic hyperplasia that mainly involves the skin, mucous membranes, and joints. The typical clinical features include papules, nodules, and arthritis. MRH lesions are relatively extensive but small and scattered. Joint inflammation is characterized by diffuse symmetric polyarthritis as the first symptom, which can be severe and disabling due to destructive joint changes. MRH is easily misdiagnosed in clinical practice. Here, we report the case of an elderly male patient who presented with polyarticular pain in the hip and interphalangeal joints as the first manifestation, followed by the development of large, isolated, bulging skin nodules, which are atypical MRH lesions. This is rare in all MRH case reports, and we made the correct diagnosis by combining skin histopathology, immunohistochemistry, and other clinical examinations. We performed surgical treatment on the local skin lesions of this patient. This case suggests that clinicians should actively correlate the condition and accurately diagnose MRH when encountering atypical skin changes or other diseases as the first symptom and explore the mechanisms of MRH and other clinical manifestations

    Investigating citrullinated proteins in tumour cell lines

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    Bacterial diversity and community in Qula from the Qinghai–Tibetan Plateau in China

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    Qula is a cheese-like product usually prepared with unpasteurized yak milk under open conditions, with both endogenous and exogenous microorganisms involved in the fermentation process. In the present study, 15 Qula samples were collected from five different regions in China to investigate the diversity of microbial communities using high-throughput sequencing targeting the V3–V4 region of 16S rRNA gene. The bacterial diversity significantly differed among samples of different origins, indicating a possible effect of geography. The result also showed that microbial communities significantly differed in samples of different origin and these differences were greater at the genus than the phylum level. A total of six phyla were identified in the samples, and Firmicutes and Proteobacteria had a relative abundance >20%. A total of 73 bacterial genera were identified in the samples. Two dominant genera (Lactobacillus and Acetobacter) were common to all samples, and a total of 47 operational taxonomic units at different levels significantly differed between samples of different origin. The predicted functional genes of the bacteria present in samples also indicated differences in bacterial communities between the samples of different origin. The network analysis showed that microbial interactions between bacterial communities in Qula were very complex. This study lays a foundation for further investigations into its food ecology

    Lateral approach for insertional Achilles tendinitis with Haglund deformity

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    ObjectiveThe study aims to investigate the functional outcome of the lateral approach for insertional Achilles tendinitis (IAT) with Haglund deformity.MethodsFrom January 2016 to September 2019, 14 cases of IAT with Haglund deformity that resisted conservative treatment received surgery in our department. A lateral approach was used to debride the bony and soft tissue and reattach the insertion of the Achilles tendon. The Visual Analog Scale (VAS), American Orthopedic Foot and Ankle Score (AOFAS), and Victorian Institute of Sport Tendon Study Group-Achilles Tendinopathy score (VISA-A) were used to evaluate clinical outcomes.ResultThe mean patient age was 39.57 years at the time of surgery. The mean follow-up was 14.74 months. The mean VAS score significantly decreased from 4.86 ± 0.86 preoperatively to 1.21 ± 1.58 postoperatively (P < 0.001). The mean AOFAS score significantly improved from 66.64 ± 6.23 preoperatively to 90.21 ± 11.50 postoperatively (P < 0.001). The mean preoperative and the last follow-up VISA-A were 66 (range 56.75–69.25) and 86 (range 75.75–97.00) points, respectively (P < 0.05).ConclusionThe lateral approach was effective and safe for IAT with Haglund deformity. Moreover, the mid-term functional outcome was promising.Level of Clinical EvidenceI

    Single cell atlas for 11 non-model mammals, reptiles and birds.

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    The availability of viral entry factors is a prerequisite for the cross-species transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening of animal cells could reveal the expression patterns of viral entry genes in different hosts. However, such exploration for SARS-CoV-2 remains limited. Here, we perform single-nucleus RNA sequencing for 11 non-model species, including pets (cat, dog, hamster, and lizard), livestock (goat and rabbit), poultry (duck and pigeon), and wildlife (pangolin, tiger, and deer), and investigated the co-expression of ACE2 and TMPRSS2. Furthermore, cross-species analysis of the lung cell atlas of the studied mammals, reptiles, and birds reveals core developmental programs, critical connectomes, and conserved regulatory circuits among these evolutionarily distant species. Overall, our work provides a compendium of gene expression profiles for non-model animals, which could be employed to identify potential SARS-CoV-2 target cells and putative zoonotic reservoirs

    Entrepreneurial intention and outcome expectancy evidence from South Korea and China /

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    Focusing on the East Asian context, this study examines (1) cultural and gender differences in entrepreneurial intention, (2) the mediating effects of culture and gender on the relationships between entrepreneurial intention and expectancies of positive entrepreneurial outcomes, and (3) the results of entrepreneurial intention of females. The findings reveal that while Chinese students have a greater entrepreneurial intention than South Korean students, the relationships between entrepreneurial intention and outcome expectancies are stronger in South Korean than in Chinese students. In terms of gender, males have a greater entrepreneurial intention than females. The relationships between entrepreneurial intention and outcome expectancies are stronger in male than in female students. Social status and self-realization are the entrepreneurial outcomes that females value most

    Career decision self-efficacy and life satisfaction in China: An empirical analysis

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    Focusing on the Chinese context, the present study took a pioneering step toexamine the relationship between career decision self-efficacy (CDSE) and life satisfaction. Employing a three-dimensional CDSE model, which includes goal planning self efficacy (GPSE), information gathering self-efficacy (IGSE) and problem solving self efficacy(PSSE), we also explored the mediation mechanism underlying this relationship from the internal functioning process of CDSE (i.e., the GPSE–PSSE–life satisfaction and IGSE–PSSE–life satisfaction relationships). We then investigated the moderating role of person–environment (P–E) fit in the mediated CDSE–life satisfaction relationship. Data were collected from 786 university students. Results showed that all three dimensions of CDSE were positively related to life satisfaction. The internal process view was supported, for PSSE was found to mediate the relationships of life satisfaction with GPSE and IGSE, respectively. Additionally, P–E fit moderated the relationship between PSSE and life satisfaction. Further examinations also found a significant moderating role of P–E fit in the indirect relationships of life satisfaction with GPSE and IGSE via PSSE
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