Traumatic brain injury and abnormal moral judgment

This article explains the underlying mechanism of utilitarian decisions in Traumatic Brain Injury (TBI) patients when pondering trolley-type moral dilemmas. In the first section of the literature review, definitions of TBI, utilitarianism and abnormal moral judgment have been provided. The ventromedial prefrontal cortex (vmPFC) has been identified to be undoubtedly prominent based on a discussion of the previous contradictory evidences about the brain areas involved in causing abnormal moral judgment. Subsequently, the function of vmPFC as an emotional integration station is introduced, substantiated by functional magnetic resonance imaging studies and the dual-system theory of moral decision-making. The inability or the diminished ability to feel morally-related emotions following TBI has also been considered a causal factor of endorsement to the act of harming someone directly. Finally, the author advises a few future directions to fill the gap within current knowledge and points out the limitations of thought experiments. Overall, the paper highlighted that the atypical response pattern of moral judgment in TBI patients is attributed to the failure to generate appropriate emotions in the face of moral stimuli

Rate-Splitting Multiple Access for Uplink Massive MIMO With Electromagnetic Exposure Constraints

Over the past few years, the prevalence of wireless devices has become one of the essential sources of electromagnetic (EM) radiation to the public. Facing with the swift development of wireless communications, people are skeptical about the risks of long-term exposure to EM radiation. As EM exposure is required to be restricted at user terminals, it is inefficient to blindly decrease the transmit power, which leads to limited spectral efficiency and energy efficiency (EE). Recently, rate-splitting multiple access (RSMA) has been proposed as an effective way to provide higher wireless transmission performance, which is a promising technology for future wireless communications. To this end, we propose using RSMA to increase the EE of massive MIMO uplink while limiting the EM exposure of users. In particularly, we investigate the optimization of the transmit covariance matrices and decoding order using statistical channel state information (CSI). The problem is formulated as non-convex mixed integer program, which is in general difficult to handle. We first propose a modified water-filling scheme to obtain the transmit covariance matrices with fixed decoding order. Then, a greedy approach is proposed to obtain the decoding permutation. Numerical results verify the effectiveness of the proposed EM exposure-aware EE maximization scheme for uplink RSMA.Comment: to appear in IEEE Journal on Selected Areas in Communication

Individual participant data meta-analysis of LR-5 in LI-RADS version 2018 versus revised LI-RADS for hepatocellular carcinoma diagnosis

Background A simplification of the Liver Imaging Reporting and Data System (LI-RADS) version 2018 (v2018), revised LI-RADS (rLI-RADS), has been proposed for imaging-based diagnosis of hepatocellular carcinoma (HCC). Single-site data suggest that rLI-RADS category 5 (rLR-5) improves sensitivity while maintaining positive predictive value (PPV) of the LI-RADS v2018 category 5 (LR-5), which indicates definite HCC. Purpose To compare the diagnostic performance of LI-RADS v2018 and rLI-RADS in a multicenter data set of patients at risk for HCC by performing an individual patient data meta-analysis. Materials and Methods Multiple databases were searched for studies published from January 2014 to January 2022 that evaluated the diagnostic performance of any version of LI-RADS at CT or MRI for diagnosing HCC. An individual patient data meta-analysis method was applied to observations from the identified studies. Quality Assessment of Diagnostic Accuracy Studies version 2 was applied to determine study risk of bias. Observations were categorized according to major features and either LI-RADS v2018 or rLI-RADS assignments. Diagnostic accuracies of category 5 for each system were calculated using generalized linear mixed models and compared using the likelihood ratio test for sensitivity and the Wald test for PPV. Results Twenty-four studies, including 3840 patients and 4727 observations, were analyzed. The median observation size was 19 mm (IQR, 11–30 mm). rLR-5 showed higher sensitivity compared with LR-5 (70.6% [95% CI: 60.7, 78.9] vs 61.3% [95% CI: 45.9, 74.7]; P < .001), with similar PPV (90.7% vs 92.3%; P = .55). In studies with low risk of bias (n = 4; 1031 observations), rLR-5 also achieved a higher sensitivity than LR-5 (72.3% [95% CI: 63.9, 80.1] vs 66.9% [95% CI: 58.2, 74.5]; P = .02), with similar PPV (83.1% vs 88.7%; P = .47). Conclusion rLR-5 achieved a higher sensitivity for identifying HCC than LR-5 while maintaining a comparable PPV at 90% or more, matching the results presented in the original rLI-RADS study