107 research outputs found
Power allocation for D2D communications in heterogeneous networks
In this paper, we study power allocation for D2D communications in heterogeneous networks utilizing game theory approach to improve the performance of the whole system. Given D2D's underlay status in the system, Stackelberg game framework is well suited for the situation. In our scheme, macrocell system and femtocell system are considered as two leaders and D2D pairs are considered as the follower, forming a two-leader-one-follower Stackelberg game. The leaders act first, charging some fees from the follower for using the channel and causing interference to jeopardize their communication equality. The follower observes the leaders' behavior and develops its strategy based on the prices offered by the leaders. We analyse the procedure and obtain the Stackeberg equilibrium, which determines the optimal prices for the leaders and optimal transmit power for the follower. In the end, simulations are executed to validate the proposed allocation method, which significantly improves data rate of user equipments. ? 2014 Global IT Research Institute (GIRI).EICPCI-S(ISTP)
DL-based CSI Feedback and Cooperative Recovery in Massive MIMO
In this paper, we exploit the correlation between nearby user equipment (UE)
and develop a deep learning-based channel state information (CSI) feedback and
cooperative recovery framework, CoCsiNet, to reduce the feedback overhead. The
CSI information can be divided into two parts: shared by nearby UE and owned by
individual UE. The key idea of exploiting the correlation is to reduce the
overhead used to repeatedly feedback shared information. Unlike in the general
autoencoder framework, an extra decoder and a combination network are added at
the base station to recover the shared information from the feedback CSI of two
nearby UE and combine the shared and individual information, respectively, but
no modification is performed at the UEs. For a UE with multiple antennas, we
also introduce a baseline neural network architecture with long short-term
memory modules to extract the correlation of nearby antennas. Given that the
CSI phase is not sparse, we propose two magnitude-dependent phase feedback
strategies that introduce statistical and instant CSI magnitude information to
the phase feedback process, respectively. Simulation results on two different
channel datasets show the effectiveness of the proposed CoCsiNet.Comment: This work has been submitted to the IEEE for possible publication.
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Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety.
O-GlcNAcase (OGA) is the only enzyme responsible for removing N-acetyl glucosamine (GlcNAc) attached to serine and threonine residues on proteins. This enzyme plays a key role in O-GlcNAc metabolism. However, the structural features of the sugar moiety recognized by human OGA (hOGA) remain unclear. In this study, a set of glycopeptides with modifications on the GlcNAc residue, were prepared in a recombinant full-length human OGT-catalyzed reaction, using chemoenzymatically synthesized UDP-GlcNAc derivatives. The resulting glycopeptides were used to evaluate the substrate specificity of hOGA toward the sugar moiety. This study will provide insights into the exploration of probes for O-GlcNAc modification, as well as a better understanding of the roles of O-GlcNAc in cellular physiology
Macroscopic entanglement between ferrimagnetic magnons and atoms via crossed optical cavity
We consider a two-dimensional opto-magnomechanical (OMM) system including two
optical cavity modes, a magnon mode, a phonon mode, and a collection of
two-level atoms. In this study, we demonstrate the methodology for generating
stationary entanglement between two-level atoms and magnons, which are
implemented using two optical cavities inside the setup. Additionally, we
investigate the efficiency of transforming entanglement from atom-phonon
entanglement to atom-magnon entanglement. The magnons are stimulated by both a
bias magnetic field and a microwave magnetic field, and they interact with
phonons through the mechanism of magnetostrictive interaction. This interaction
generates magnomechanical displacement, which couples to an optical cavity via
radiation pressure. We demonstrate that by carefully selecting the frequency
detuning of an optical cavity, it is possible to achieve an increase in
bipartite entanglements. Furthermore, this improvement is found to be resistant
to changes in temperature. The entanglement between atoms and magnons plays a
crucial role in the construction of hybrid quantum networks. Our modeling
approach exhibits potential applications in the field of magneto-optical trap
systems as well.Comment: arXiv admin note: text overlap with arXiv:1903.00221 by other author
Multi-channel quantum noise suppression and phase-sensitive modulation in a hybrid optical resonant cavity system
Quantum noise suppression and phase-sensitive modulation of continuously
variable in vacuum and squeezed fields in a hybrid resonant cavity system are
investigated theoretically. Multiple dark windows similar to electromagnetic
induction transparency (EIT) are observed in quantum noise fluctuation curve.
The effects of pumping light on both suppression of quantum noise and control
the widths of dark windows are carefully analyzed, and the saturation point of
pumping light for nonlinear crystal conversion is obtained. We find that the
noise suppression effect is strongly sensitive to the pumping light power. The
degree of noise suppression can be up to 13.9 dB when the pumping light power
is 6.5 Beta_th. Moreover, a phase-sensitive modulation scheme is demonstrated,
which well fills the gap that multi-channel quantum noise suppression is
difficult to realize at the quadrature amplitude of squeezed field. Our result
is meaningful for various applications in precise measurement physics, quantum
information processing and quantum communications of system-on-a-chip
Identification of avian polyomavirus and its pathogenicity to SPF chickens
The research aimed to study an Avian polyomavirus strain that was isolated in Shandong, China. To study the pathogenicity of APV in SPF chickens, and provide references for epidemiological research and disease prevention and control of APV. The genetic characterization of APV strain (termed APV-20) was analyzed and the pathogenicity of APV was investigated from two aspects: different age SPF chickens, and different infection doses. The results revealed that the APV-20 exhibits a nucleotide homology of 99% with the other three APV strains, and the evolution of APV In China was slow. In addition, the APV-20 infection in chickens caused depression, drowsiness, clustering, and fluffy feathers, but no deaths occurred in the infected chickens. The main manifestations of necropsy, and Hematoxylin and Eosin staining (HE) showed that one-day-old SPF chickens were the most susceptible, and there was a positive correlation between viral load and infection dose in the same tissue. This study showed that SPF chickens were susceptible to APV, and an experimental animal model was established. This study can provide a reference for the pathogenic mechanism of immune prevention and control of APV
Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety
O-GlcNAcase (OGA) is the only enzyme responsible for removing N-acetyl glucosamine (GlcNAc) attached to serine and threonine residues on proteins. This enzyme plays a key role in O-GlcNAc metabolism. However, the structural features of the sugar moiety recognized by human OGA (hOGA) remain unclear. In this study, a set of glycopeptides with modifications on the GlcNAc residue, were prepared in a recombinant full-length human OGT-catalyzed reaction, using chemoenzymatically synthesized UDP-GlcNAc derivatives. The resulting glycopeptides were used to evaluate the substrate specificity of hOGA toward the sugar moiety. This study will provide insights into the exploration of probes for O-GlcNAc modification, as well as a better understanding of the roles of O-GlcNAc in cellular physiology
Molecular characterization of sub-frontal recurrent medulloblastomas reveals potential clinical relevance
BackgroundSingle recurrence in the sub-frontal region after cerebellar medulloblastoma (MB) resection is rare and the underlying molecular characteristics have not been specifically addressed.MethodsWe summarized two such cases in our center. All five samples were molecularly profiled for their genome and transcriptome signatures.ResultsThe recurrent tumors displayed genomic and transcriptomic divergence. Pathway analysis of recurrent tumors showed functional convergence in metabolism, cancer, neuroactive ligand–receptor interaction, and PI3K-AKT signaling pathways. Notably, the sub-frontal recurrent tumors had a much higher proportion (50–86%) of acquired driver mutations than that reported in other recurrent locations. The acquired putative driver genes in the sub-frontal recurrent tumors functionally enriched for chromatin remodeler-associated genes, such as KDM6B, SPEN, CHD4, and CHD7. Furthermore, the germline mutations of our cases showed a significant functional convergence in focal adhesion, cell adhesion molecules, and ECM–receptor interaction. Evolutionary analysis showed that the recurrence could be derived from a single primary tumor lineage or had an intermediate phylogenetic similarity to the matched primary one.ConclusionRare single sub-frontal recurrent MBs presented specific mutation signatures that might be related to the under-dose radiation. Particular attention should be paid to optimally covering the sub-frontal cribriform plate during postoperative radiotherapy targeting
Finishing the euchromatic sequence of the human genome
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Dynamic Calibration Method of Sensor Drift Fault in HVAC System Based on Bayesian Inference
Sensor drift fault calibration is essential to maintain the operation of heating, ventilation and air conditioning systems (HVAC) in buildings. Bayesian inference (BI) is becoming more and more popular as a commonly used sensor fault calibration method. However, this method focused mainly on sensor bias fault, and it could be difficult to calibrate drift fault that changes with time. Therefore, a dynamic calibration method for sensor drift fault of HVAC systems based on BI is developed. Taking the drift fault calibration of the chilled water supply temperature sensor of the chiller as an example, the performance of the proposed dynamic calibration method is evaluated. Results show that the combination of the Exponentially Weighted Moving-Average (EWMA) method with high detection accuracy and the proposed BI dynamic calibration method can effectively improve the calibration accuracy of drift fault, and the Mean Absolute Percentage Error (MAPE) value between the calibrated and normal data is less than 5%
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