8,798 research outputs found
Double occupancies in confined attractive fermions on optical lattices
We perform a numerical study of a one-dimensional Fermion-Hubbard model in
harmonic traps within the Thomas-Fermi approximation based on the exact
Bethe-ansatz solution. The phase diagram is shown for the systems of
attractive interactions ( is the characteristic density and the
interaction strength scaled in units of the hopping parameter.). We study the
double occupancy, the local central density and their derivatives. Their roles
are discussed in details in detecting the composite phases induced by the
trapping potential.Comment: 4 pages, 4 figures, submitte
Impact of Background Radiation on the Long Wave Infrared Radiation Characteristics of Aircraft at High Altitude
Reflected background infrared radiation is an important contributor to the aircraft total infrared radiation. A reverse Monte Carlo ray tracing method to compute the infrared radiation signature of aircraft was introduced. The impact of atmospheric and ground radiation on the long wave infrared radiation signature of aircraft at the altitude of 11 km is analysed. The flight speed is Mach 0.8. The horizontal detection directions, downward detection directions and upward detection directions are considered. The results show that in the horizontal plane, the ratio of reflected background infrared radiation to self infrared radiation is about 10 per cent in summer, and 7 per cent in winter; the ratio values distributed in the front and side of the aircraft are bigger than that in the rear; and the existence of atmospheric and ground infrared radiation makes the apparent radiance temperature of the lower part of the aircraft higher than that of the upper part of the aircraft.
Potential protein biomarkers for burning mouth syndrome discovered by quantitative proteomics.
Burning mouth syndrome (BMS) is a chronic pain disorder characterized by severe burning sensation in normal looking oral mucosa. Diagnosis of BMS remains to be a challenge to oral healthcare professionals because the method for definite diagnosis is still uncertain. In this study, a quantitative saliva proteomic analysis was performed in order to identify target proteins in BMS patients' saliva that may be used as biomarkers for simple, non-invasive detection of the disease. By using isobaric tags for relative and absolute quantitation labeling and liquid chromatography-tandem mass spectrometry to quantify 1130 saliva proteins between BMS patients and healthy control subjects, we found that 50 proteins were significantly changed in the BMS patients when compared to the healthy control subjects ( p ≤ 0.05, 39 up-regulated and 11 down-regulated). Four candidates, alpha-enolase, interleukin-18 (IL-18), kallikrein-13 (KLK13), and cathepsin G, were selected for further validation. Based on enzyme-linked immunosorbent assay measurements, three potential biomarkers, alpha-enolase, IL-18, and KLK13, were successfully validated. The fold changes for alpha-enolase, IL-18, and KLK13 were determined as 3.6, 2.9, and 2.2 (burning mouth syndrome vs. control), and corresponding receiver operating characteristic values were determined as 0.78, 0.83, and 0.68, respectively. Our findings indicate that testing of the identified protein biomarkers in saliva might be a valuable clinical tool for BMS detection. Further validation studies of the identified biomarkers or additional candidate biomarkers are needed to achieve a multi-marker prediction model for improved detection of BMS with high sensitivity and specificity
Analytical Studies on a Modified Nagel-Schreckenberg Model with the Fukui-Ishibashi Acceleration Rule
We propose and study a one-dimensional traffic flow cellular automaton model
of high-speed vehicles with the Fukui-Ishibashi-type (FI) acceleration rule for
all cars, and the Nagel-Schreckenberg-type (NS) stochastic delay mechanism. By
using the car-oriented mean field theory, we obtain analytically the
fundamental diagrams of the average speed and vehicle flux depending on the
vehicle density and stochastic delay probability. Our theoretical results,
which may contribute to the exact analytical theory of the NS model, are in
excellent agreement with numerical simulations.Comment: 3 pages previous; now 4 pages 2 eps figure
Efficacy of Ultrasound-guided Radiofrequency Ablation of Parathyroid Hyperplasia: Single Session vs. Two-Session for Effect on Hypocalcemia
To evaluate safety and efficacy of one- vs. two-session radiofrequency ablation (RFA) of parathyroid hyperplasia for patients with secondary hyperparathyroidism (SHPT) and to compare the outcome of both methods on hypocalcemia. Patients with secondary hyperparathyroidism underwent ultrasound guided RFA of parathyroid hyperplasia. Patients were alternately assigned to either group 1 (n = 28) with RFA of all 4 glands in one session or group 2 (n = 28) with RFA of 2 glands in a first session and other 2 glands in a second session. Serum parathyroid hormone (PTH), calcium, phosphorus and alkaline phosphatase (ALP) values were measured at a series of time points after RFA. RFA parameters, including operation duration and ablation time and hospitalization length and cost, were compared between the two groups. Mean PTH decreased in group 1 from 1865.18 ± 828.93 pg/ml to 145.72 ± 119.27 pg/ml at 1 day after RFA and in group 2 from 2256.64 ± 1021.72 pg/ml to 1388.13 ± 890.15 pg/ml at 1 day after first RFA and to 137.26 ± 107.12 pg/ml at 1 day after second RFA. Group 1\u27s calcium level decreased to 1.79 ± 0.31 mmol/L at day 1 after RFA and group 2 decreased to 1.89 ± 0.26 mmol/L at day 1 after second session RFA (P \u3c 0.05). Multivariate analysis showed that hypocalcemia was related to serum ALP. Patients with ALP ≥ 566 U/L had lower calcium compared to patients with ALP \u3c 566 U/L up to a month after RFA (P \u3c 0.05). Group 1\u27s RFA time and hospitalization were shorter and had lower cost compared with Group 2. US-guided RFA of parathyroid hyperplasia is a safe and effective method for treating secondary hyperparathyroidism. Single-session RFA was more cost-effective and resulted in a shorter hospital stay compared to two sessions. However, patients with two-session RFA had less hypocalcemia, especially those with high ALP
The use of High-Fat/Carbohydrate Diet-Fed and Streptozotocin-Treated Mice as a Suitable Animal Model of Type 2 Diabetes Mellitus
This study defined a mouse model of type 2 diabetes that closely simulated the development and metabolic abnormalities of the human disease. Male C57BL/6J mice were fed with diet enriched in fat and simple carbohydrate for 6 weeks and then injected with streptozotocin (STZ, 150 mg/kg intraperitoneally) to develop type 2 diabetes. High-fat/carbohydrate-fed mice showed similar blood glucose concentrations to chow-fed mice, but higher insulin concentrations (P<0.01). Hyperglycemia (17.6±3.27 mmol/L) was observed in these mice after STZ injection, and the insulin concentrations decreased to the level comparable to, or still higher than, the normal. The model mice showed impaired glucose tolerance in the oral glucose tolerance test (OGTT), and insulin resistance in the insulin tolerance test (ITT). Moreover, these animals had lower glycogen storage (P<0.001), higher serum free fatty acid (P<0.001), and higher triglycerides (P<0.05) levels compared with control mice. Furthermore, the model mice were sensitive to the glucose lowering effect of metformin. In conclusion, this mouse model could be considered as one of the suitable animal models for type 2 diabetes mellitus, and hence can reasonably be used for type 2 diabetes pathophysiological research and therapeutic-compound evaluation.
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