6 research outputs found

    Diagnostic algorithm to manage patients with autosomal dominant polycystic kidney disease (ADPKD) presenting with suspected acute cyst complication.

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    <p>*, On the basis of the conventional management (including blood and urine analyses and abdomen imaging) of any patient with febrile abdominal pain in emergency conditions (33).</p

    COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19

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    The COVID-19 pandemic continues to pose a major public health threat, especially in countries with low vaccination rates. To better understand the biological underpinnings of SARS-CoV-2 infection and COVID-19 severity, we formed the COVID-19 Host Genetics Initiative1. Here we present a genome-wide association study meta-analysis of up to 125,584 cases and over 2.5 million control individuals across 60 studies from 25 countries, adding 11 genome-wide significant loci compared with those previously identified2. Genes at new loci, including SFTPD, MUC5B and ACE2, reveal compelling insights regarding disease susceptibility and severity.</p
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