535 research outputs found
From Known-Plaintext Security to Chosen-Plaintext Security
We present a new encryption mode for block ciphers. The mode is efficient and is secure against chosen-plaintext attack (CPA) already if the underlying symmetric cipher is secure against known-plaintext attack (KPA). We prove that known (and widely used) encryption modes as CBC mode and counter mode do not have this property. In particular, we prove that CBC mode using a KPA secure cipher is KPA secure, but need not be CPA secure, and we prove that counter mode using a KPA secure cipher need not be even KPA secure. The analysis is done in a concrete security framework
Model-based Speech Enhancement for Intelligibility Improvement in Binaural Hearing Aids
Speech intelligibility is often severely degraded among hearing impaired
individuals in situations such as the cocktail party scenario. The performance
of the current hearing aid technology has been observed to be limited in these
scenarios. In this paper, we propose a binaural speech enhancement framework
that takes into consideration the speech production model. The enhancement
framework proposed here is based on the Kalman filter that allows us to take
the speech production dynamics into account during the enhancement process. The
usage of a Kalman filter requires the estimation of clean speech and noise
short term predictor (STP) parameters, and the clean speech pitch parameters.
In this work, a binaural codebook-based method is proposed for estimating the
STP parameters, and a directional pitch estimator based on the harmonic model
and maximum likelihood principle is used to estimate the pitch parameters. The
proposed method for estimating the STP and pitch parameters jointly uses the
information from left and right ears, leading to a more robust estimation of
the filter parameters. Objective measures such as PESQ and STOI have been used
to evaluate the enhancement framework in different acoustic scenarios
representative of the cocktail party scenario. We have also conducted
subjective listening tests on a set of nine normal hearing subjects, to
evaluate the performance in terms of intelligibility and quality improvement.
The listening tests show that the proposed algorithm, even with access to only
a single channel noisy observation, significantly improves the overall speech
quality, and the speech intelligibility by up to 15%.Comment: after revisio
Bacterial viruses enable their host to acquire antibiotic resistance genes from neighbouring cells
Prophages are quiescent viruses located in the chromosomes of bacteria. In the human
pathogen, Staphylococcus aureus, prophages are omnipresent and are believed to be responsible
for the spread of some antibiotic resistance genes. Here we demonstrate that release of
phages from a subpopulation of S. aureus cells enables the intact, prophage-containing
population to acquire beneficial genes from competing, phage-susceptible strains present in
the same environment. Phage infection kills competitor cells and bits of their DNA are
occasionally captured in viral transducing particles. Return of such particles to the prophagecontaining
population can drive the transfer of genes encoding potentially useful traits such
as antibiotic resistance. This process, which can be viewed as ‘auto-transduction’, allows
S. aureus to efficiently acquire antibiotic resistance both in vitro and in an in vivo virulence
model (wax moth larvae) and enables it to proliferate under strong antibiotic selection
pressure. Our results may help to explain the rapid exchange of antibiotic resistance genes
observed in S. aureus
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