The Influence of Autonomic Dysfunction Associated with Aging and Type 2 Diabetes on Daily Life Activities

Type 2 diabetes (T2D) and ageing have well documented effects on every organ in the body. In T2D the autonomic nervous system is impaired due to damage to neurons, sensory receptors, synapses and the blood vessels. This paper will concentrate on how autonomic impairment alters normal daily activities. Impairments include the response of the blood vessels to heat, sweating, heat transfer, whole body heating, orthostatic intolerance, balance, and gait. Because diabetes is more prevalent in older individuals, the effects of ageing will be examined. Beginning with endothelial dysfunction, blood vessels have impairment in their ability to vasodilate. With this and synaptic damage, the autonomic nervous system cannot compensate for effectors such as pressure on and heating of the skin. This and reduced ability of the heart to respond to stress, reduces autonomic orthostatic compensation. Diminished sweating causes the skin and core temperature to be high during whole body heating. Impaired orthostatic tolerance, impaired vision and vestibular sensing, causes poor balance and impaired gait. Overall, people with T2D must be made aware and counseled relative to the potential consequence of these impairments

The Effect of an 8-Minute Yoga Breathing Program on Fitness, Weight Loss and Breathing Capacity

This was a single blinded randomized study with an intervention group and a control group to examine a modification in lifestyle and an 8-minute exercise session each day to lose weight. Fifty-seven female subjects participated. Subjects underwent girth measurements at the umbilicus, hips, thigh and upper arm; weight, height (for BMI), body fat, heart rate, blood pressure, abdominal strength, leg strength, arm strength, sedentary O2 saturation, treadmill challenged O2 saturation, resting metabolism (which includes fat metabolism), and lung capacity. Measures were repeated at baseline and the end of the 6-week period. During the 6-week period, they followed a healthy recommended diet with high volumes of vegetables and fruit and 8 minutes of exercise each day. In the investigational group, the average weight loss was 4.85 KG over the 6-week period, BMI was reduced 1.79 at the end of the 6 weeks, a significant loss (p\u3c0.01). Body fat in this group was reduced by 5.87 percent, the average girth at the showed an average loss in circumference of 5.9 cm over the 6-week period. For the hip, the average loss in circumference was 6.28 cm, for the thigh the average loss in circumference in the investigational group was 5.0 cm, and for the upper arm reduced girth by 2.61 cm. For strength for the investigational group, for the abdominals the increase was 11.3 Kg, for the leg it was 6.0 kg and for the arm it was 4.8 kg. All of these increases were significant (p\u3c0.01). The basal metabolic rate, in the investigational group after the 6 weeks increased to 31.1 cc/kg lean body mass. The fat burning doubled in the investigational group. In conclusion, subjects slept better, had high oxygen saturation and better strength and excellent weight and fat loss with this program

Brief Note: The Influence of the Menstrual Cycle on the Blood Flow Through Muscle During Isometric Exercise

Author Institution: Departments of Engineering and Physiology, Wright State Universit

Active Material Properties of the Myocardium: Correlation With Left Ventricular Function in Man

Author Institution: Department of Engineering and Physiology, Wright State UniversityThe effects of anisotrophy and nonhomogeneity of the ventricular myocardium as represented by a linear increase in the midwall effective modulus of elasticity were investigated in the present study, specifically as they effect the circumferential stress distribution. Various studies are presented suggesting a linear increase in the effective modulus of elasticity from endocardium to epicardium. In our study, this increase in the effective modulus was constrained by the approximation that stress per unit sarcomere length is constant. We evaluated 12 functionally normal cases and 9 functionally abnormal cases. The stress distribution for the 9 functionally abnormal cases was calculated, first with the normal and secondly with the abnormal variation in the modulus of elasticity. Assuming the myocardium has constant material properties that do not change with functional decomposition, the stress distributions in the first calculations indicated higher stresses through the inner half of the myocardium and lower stresses through the outer half of the myocardium as compared to the second. This finding suggests that the inner fibers are overloaded and the outer fibers are underloaded in left ventricular decompensation. The difference between the first and second stress distributions averaged 26% (range: 11% to 48%). A useful, clinical, and quantitative measure of stress loading of the sarcomeres in functionally normal and abnormal left ventricles is proposed

The Effect of Continuous Heat Wraps on Balance and Gait in the Elderly

Background: In an ageing geriatric population, tremor and poor balance become more pronounced and can lead to falls. Falls are the leading cause of mortality in this population. Continuous heat wraps have been shown to increase tissue flexibility. It was the purpose of this study to examine the effects of heat on balance and gait in the elderly with impaired mobility. Subjects: Twenty people with impaired mobility (assessed as a score of more than 4 on the “Stepping On” questionnaire) were tested with a balance platform after using ThermaCare continuous heat wraps on their legs and knees for 6 days. Data was collected at day 0 (before heat) and day 7. The average age was 60.3+/-8.3 years. The loss in mobility could not be due to pain killers or other drugs the person was taking that may reduce mobility. Half of the subjects started with a week of heat treatment and half were no heat controls. At the end of the first arm, there was a one week washout and the groups were reversed. Methods: Balance was assessed on a custom made balance platform during 8 different balance tasks lasting 10 seconds each and presented at random. Tremor was measured during the balance tasks at 8 and 24 Hertz. Gait was assessed by the “timed up and go” test. Results: Muscle tremor was reduced; balance and gait were significantly improved, after 6 sessions of heat application on the legs. Conclusion: As per the literature, this improvement in balance should reduce the chance of falls in this population

Six Weeks Habituation of Simulated Barefoot Running Induces Neuromuscular Adaptations and Changes in Foot Strike Patterns in Female Runners

BACKGROUND: The aim of this study was to examine the effects of a 6-week training program of simulated barefoot running (SBR) on running kinetics in habitually shod (wearing shoes) female recreational runners.MATERIAL AND METHODS: Twelve female runners age 25.7±3.4 years gradually increased running distance in Vibram FiveFingers minimal shoes over a 6-week period. The kinetic analysis of treadmill running at 10 Km/h was performed pre- and post-intervention in shod running, non-habituated SBR, and habituated SBR conditions. Spatiotemporal parameters, ground reaction force components, and electromyography (EMG) were measured in all conditions.RESULTS: Post-intervention data indicated a significant decrease across time in the habituation SBR for EMG activity of the tibialis anterior (TA) in the pre-activation and absorptive phase of running (PCONCLUSIONS: The findings of this study indicate that changes in motor patterns in previously habitually shod runners are possible and can be accomplished within 6 weeks. Non-habituation SBR did not show a significant neuromuscular adaptation in the EMG activity of TA and GAS as manifested after 6 weeks of habituated SBR

Evidence-Based Use of Cold for Plantar Fasciitis

Objective The purpose of this study was to examine the effect of cold applied the night before or in the morning on pain and symptoms of plantar fasciitis. Design Experimental study. Methods Thirty subjects with plantar fasciitis were recruited for this study. Subjects with plantar fasciitis either had no intervention, cold applied (20 minutes) at night before bed, or 20 minutes in the morning upon wakening. Plantar fascia tenderness and pain were evaluated. There were ten subjects in each group. Measures included visual analog scale, plantar facial thickness via high resolution ultrasound, algometer measure, and range of motion of the ankle and foot. There were 3 groups of 10 subjects, control (no intervention), cold the night before bed, and cold in the morning before rising. Results The greatest relief of symptoms was cold used at bedtime the night before the measurements. Cold used in the morning was not as effective as cold used in the evening before bed. Cold use reduced the thickness of the plantar fascia and irritation. There was a 13% reduction in plantar fascia thickness with cold the night before (p\u3c0.05), a 44% reduction in pain and an 86 % increase in the force that could be applied to the bottom of the foot without pain (p\u3c0.05). Conclusions Cold applied for 20 minutes prior bedtime is effective for reduced symptomology caused by plantar fascia inflammation

The Effect of ThermaCare Heat Wraps on Balance and Mobility in Seniors with Impaired Gait - A Cross Over Study

To examine if the use of heat at home can result in better quality and safer mobility in the elderly with gait and balance impairments. Setting: Randomized longitudinal cross over study design in a clinical setting. Methods: 20 people with impaired mobility (assessed as a score of more than 4 on the Stepping On questionnaire) were tested with a multi-camera gait analysis system, a treadmill with pressure sensors, a balance platform and the timed up and go and walking speed tests before and after using ThermaCare continuous heat wraps on their legs and knees for 6 days at 4 hours per day. The loss in mobility could not be due to pain killers or other drugs that reduced mobility. Results: Muscle tremor was reduced, mobility of the joints was improved, balance was significantly improved, and gait was improved after 6 sessions of heat application on the legs. As per the literature, this should reduce the chance of falls in this population. Conclusion: Using continuous heat wraps may be an important adjunct for improving gait in the elderly with gait impairments

Can eccentric exercise of the lower limb be made more efficiently, a pilot study

Abstract Background: Eccentric Exercise has been shown to be more effective in building muscle and healing damaged tissue than concentric or isometric exercise. It has also been shown to be effective in increasing motor control. But the duration of therapeutic exercise in physical therapy is limited by insurance to 30-60 minutes a day. Objectives: Four standard therapy eccentric exercises of the lower limbs were compared (toe raise, ball exercise, side lying eccentric exercise and incline board exercise) to a trainer called the BTE Eccentron to see if the efficiency of exercise could be increased using one exercise session to meet or beat the four individual exercises. Subjects and Methods: The study examined eight randomly selected participants with no known medical conditions (neurological or orthopedic) that would preclude their participation (age=24.1+/-2.1 years height=168.9+/-6.4 cm BMI=23.2+/-3.2). EMG was used to assess muscle recruitment in each exercise. The muscles studies were the gastrocnemius, hamstring, hip adductors, and quadriceps muscles. Results: Muscle use on the eccentron was almost double that of the other exercises. Thus, making therapy more efficient. One single exercise bout showed more muscle activation during eccentric exercise than the other four exercises, with an average muscle use almost 4 times higher on the eccentron. Conclusion: The Eccentron offers a considerable advantage for clinical treatment making exercise and neuromuscular training more efficient

17β-Estradiol Induced Effects on Anterior Cruciate Ligament Laxness and Neuromuscular Activation Patterns in Female Runners

Background: To investigate the effects of 17β-Estradiol across phases of menstrual cycle on the laxness of the anterior cruciate ligament (ACL) and the neuromuscular control around the knee joint in female runners. Methods: Twelve healthy female runners, who reported normal menstrual cycles for the previous 6 months were tested twice across one complete menstrual cycle for serum levels of 17β Estradiol (E), and knee joint laxity (KJL). Electromyographic (EMG) activity of the quadriceps and hamstrings muscles was also recorded during running on a treadmill. The changes in the EMG activity, KJL, and hormonal concentrations were recorded for each subject during the follicular and the ovulatory phases across the menstrual cycle. Results: An observed increased in KJL in response to peak E during the ovulatory phase, was associated with increased preactivity of the hamstring muscle before foot impact (p \u3c 0.001). A consistent pattern was also observed in the firing of the quadriceps muscle recruitment pattern throughout the follicular phase associated with decreased hamstring recruitment pattern during weight acceptance phase of running (p = 0.02). Additionally, low ratio of medial to lateral quadriceps recruitment was associated with a significant reduction of the quadriceps to hamstring cocontraction ratio during the follicular phase. Conclusions: Changes in KJL during the menstrual cycle in response to 17β-Estradiol fluctuations changes the neuromuscular control around the knee during running. Female runners utilize different neuromuscular control strategies during different phases of the menstrual cycle which may contribute to increase ACL injury risk