Technology, Alienation, and the South Korean Factory Worker

A thesis presented to the faculty of the School of Social Sciences at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Arts by Jerre R. Brimer on July 29, 1977

Cerebral Abscess and \u3ci\u3eCephenemyia phobifer\u3c/i\u3e in a Mule Deer in Central Nebraska

A wild yearling male mule deer (Odocoileus hemionus) from south central Nebraska was submitted to the University of Nebraska North Platte Station Diagnostic Laboratory with the history of severe depression, slight incoordination, and visual impairment. Gross examination revealed a large abcess involving approximately 65-75% of the cebral hemispheres of the brain and approximately bots in the retropharyngeal pouches

Cerebral Abscess and \u3ci\u3eCephenemyia phobifer\u3c/i\u3e in a Mule Deer in Central Nebraska

A wild yearling male mule deer (Odocoileus hemionus) from south central Nebraska was submitted to the University of Nebraska North Platte Station Diagnostic Laboratory with the history of severe depression, slight incoordination, and visual impairment. Gross examination revealed a large abcess involving approximately 65-75% of the cebral hemispheres of the brain and approximately bots in the retropharyngeal pouches

Use of 18F-2-Fluorodeoxyglucose to Label Antibody Fragments for Immuno-Positron Emission Tomography of Pancreatic Cancer

We generated 18F-labeled antibody fragments for positron emission tomography (PET) imaging using a sortase-mediated reaction to install a trans-cyclooctene-functionalized short peptide onto proteins of interest, followed by reaction with a tetrazine-labeled-18F-2-deoxyfluoroglucose (FDG). The method is rapid, robust, and site-specific (radiochemical yields > 25%, not decay corrected). The availability of 18F-2-deoxyfluoroglucose avoids the need for more complicated chemistries used to generate carbon–fluorine bonds. We demonstrate the utility of the method by detecting heterotopic pancreatic tumors in mice by PET, using anti-Class II MHC single domain antibodies. We correlate macroscopic PET images with microscopic two-photon visualization of the tumor. Our approach provides easy access to 18F-labeled antibodies and their fragments at a level of molecular specificity that complements conventional 18F-FDG imaging

Effects of Copper and Selenium Injections on Cow Productivity and Concentration of Copper in Liver Biopsy Samples

In the conditions of the study when additional copper and selenium were provided, cow reproduction and calf performance were not improved

Dietary Exposure of Fathead Minnows to the Explosives TNT and RDX and to the Pesticide DDT using Contaminated Invertebrates

Explosive compounds have been released into the environment during manufacturing, handling, and usage procedures. These compounds have been found to persist in the environment and potentially promote detrimental biological effects. The lack of research on bioaccumulation and bioconcentration and especially dietary transfer on aquatic life has resulted in challenges in assessing ecological risks. The objective of this study was to investigate the potential trophic transfer of the explosive compounds 2,4,6-trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) using a realistic freshwater prey/predator model and using dichlorodiphenyltrichloroethane (DDT), a highly bioaccumulative compound, to establish relative dietary uptake potential. The oligochaete worm Lumbriculus variegatus was exposed to 14C-labeled TNT, RDX or DDT for 5 hours in water, frozen in meal-size packages and subsequently fed to individual juvenile fathead minnows (Pimephales promelas). Fish were sampled for body residue determination on days 1, 2, 3, 4, 7, and 14 following an 8-hour gut purging period. Extensive metabolism of the parent compound in worms occurred for TNT but not for RDX and DDT. Fish body residue remained relatively unchanged over time for TNT and RDX, but did not approach steady-state concentration for DDT during the exposure period. The bioaccumulation factor (concentration in fish relative to concentration in worms) was 0.018, 0.010, and 0.422 g/g for TNT, RDX and DDT, respectively, confirming the expected relatively low bioaccumulative potential for TNT and RDX through the dietary route. The experimental design was deemed successful in determining the potential for trophic transfer of organic contaminants via a realistic predator/prey exposure scenario