Implementation of Organizational Conduct and Operation Management in Golf Projekt

Project Golf represents a series of activities and work with an irretrievable and unique goal - the ultimate goal being the launch of golf courts and accompanying facilities. Since the golf court project needs to be completed within a certain time period, certain costs and executive limitations in an unstable environment by effectively and efficiently using limited resource, it is clear that golf projects are specifically and demanding. Management and golf project realization is a complex dynamical process and it is necessary for its fulfilment to gather an adequate team of experts lead by a project manager. The scientific discipline of organizational conduct is dealing with actions and attitudes that people are showing in an organization and a project team. Operation management manages those business activities determining all the activities inside an organization tied to transforming input into output and in that way encompass all business functions. Since golf court management and realization is a very complex and demanding process it is clear that these two disciplines need to be applied in golf court realization. This paper deals with these issues.organizational conduct, operation management, project teams and golf projects

QSAR Model for Predicting Antioxidan Capacity of Some Polyphenolic Antioxidants

Quantitative structure–activity relationship model (QSAR models) is useful method for predicting antioxidant capacity of a molecule based on some chemical-physics properties. In our development of QSAR model are included 21 structural similar antioxidants. It is shown that taking into account some thermodynamical and thermochemical parameters of antioxidant and chemical activity is possible to generate fair antiradical QSAR models

Examination of Electron Transfer Mechanism of Cyanidin

Cyanidin, as one important plant pigment, was theoretically (at M05-2X/6-311+G(d,p) level of theory) investigated for its ability to scavenge potentially, highly damaging hydroxyl radical. Free radical scavenging of cyanidin was studied through electron transfer mechanism – ET (the second step in SPLET mechanism) in water and ethanol, as solvents. Examination was performed using density functional theory (DFT) and Marcus theory. Based on the thermochemical and kinetic data, it is clear that O‒H group of cyanidin in position 3` is the most suitable for reaction with hydroxyl radical through mentioned antioxidant mechanism

Antioksidativna i inhibitorska aktivnost Alizarin-2-glikozida

In this paper was investigated the antioxidative activity of alizarin-2-glycoside. All results were obtained using the DFT method. For calculations, the M06-2X method was used in combination with the 6-311++G(d,p) base set. Water was used as a solvent. The values of enthalpy were used as thermodynamic parameters on the basis of which the antioxidative capacity of alizarin-2-glycoside was evaluated. The Molecular Docking method was used for assessing the ability of alizarin-2-glycoside to inhibit the negative effect of P-glycoprotein.U ovom radu je ispitana antioksidativna aktivnost alizarin-2-glikozida. Svi rezultati dobijeni su primenom DFT metode. Za izračunavanja je korišćena M06-2X metoda u kombinaciji sa 6-311++G(d,p) bazisnim skupom. Kao rastvarač korišćena je voda. Vrednosti entalpija korišćene su kao termodinamički parametri na osnovu kojih je procenjen antioksidativni kapacitet alizarin-2-glikozida. Molecular Docking metodom procenjena je sposobnost alizarin-2-glikozida da inhibira negativan uticaj P-glikoproteina

Ligand-protein interakcije 3-(1-(3-hidroksipropilamino)etiliden)hroman-2,4-diona sa humanim C reaktivnim proteinom

The structure of the newly synthesized coumarin derivative, 3-(1-(3-hydroxypropylamino)-ethylidene)-chroman-2,4-dione, was investigated theoretically. The density functional theory calculations, with B3LYP functional (and with empirical dispersion corrections D3BJ) in combination with the 6–311+G(d,p) basis set, are performed in order to optimized the molecular structure of the investigated coumarin derivative. Molecular docking analysis was carried out in order to identify the potency of inhibition of the title molecule against human C-reactive protein. The inhibition activity was obtained for ten conformations of ligand inside protein.Struktura novo sintetisanog derivata kumarina, 3- (1- (3-hidroksipropilamino) -etiliden) -hroman-2,4-diona, ispitana je primenom teorijskih metoda. Za optimizaciju strukture ispitivanog kumarinskog derivata korišćena je teorija funkcionalne gustine: B3LYP funkcional ( sa empirijskim ispravkama disperzije D3BJ) u kombinaciji sa 6-311+G(d, p) bazisnim setom. Urađen je molekulski doking, kao i analiza dobijenih rezultata kako bi se utvrdio potencijal inhibicije molekula ispitivanog jedinjenja prema humanom C-reaktivnom proteinu. Aktivnost inhibicije izračunata je za deset potencijalnih konformacija liganda unutar proteina

HYPERLIPIDEMIA IN ACUTE PANCREATITIS: CONCOMITANT DISORDER OR A CAUSE?

Acute pancreatitis is a common condition with alcohol and gallstones being the most frequent etiologies. The aim of our study was to determine the prevalence of hyperlipidemia, its etiopathogenetic role and influence on outcomes in patients with acute pancreatitis.The study included 47 patients admitted to our clinic for acute pancreatitis during one year period. On admission patients with hyperlipidemia were compared to those without it, regarding following parameters: body mass index, Glasgow score, organ failure occurrence, local complications occurrence (pancreatic necrosis, pseudocyst, abscess, jaundice, gastric outlet syndrome), intensive care unit stay and death. The results of the study revealed high incidence of hyperlipidemia in 51% of examined acute pancreatitis patients with the prevalence of severe forms in more than half of these patients. Dominant lipid disorder was hypertriglyceridemia, followed by hypercholesterolemia. It was clearly demonstrated that patients with hyperlipidemia, especially hypertriglyceridemia, had more severe acute pancreatitis, higher incidence of complications and poorer outcome compared to normolipemic patients. Hyperlipidemia in patients with acute pancreatitis should be considered and treated by a clinician as a separate serious problem, both when being a cause and a concomitant disorder. Hypolipidemic therapy should be administered both in urgent acute pancreatitis settings and as a long-term treatment aimed to prevent inflammation recurrence by successful persistent serum lipid levels control.Key words: Hyperlipidemia, acute pancreatitis

REGULATION AND TRADING WITH GREEN HOUSE EFFECT GASES AND ADVANTAGES OF SERBIA'S ENTRY IN THE EMISSION MARKET

Modern tendency to make flexible mechanism in order to stop climate change developed new kind of market based on emission trading system. Market as regulatory mechanism is capable to stop further pollution of the environment and achieve primary goal in allocation of emission permits between those who need them and those who possess them. Modern prediction are based on opinion that carbon markets will have great impact on global economy in near future. However today his influence is miserable comparing to some other markets, even though there are several very influential trading projects that are established inside EU, one of them is EU ETS. European Union trading scheme is not only important for developed countries, but also for those who have aspiration to become part of EU. Therefore basic purpose of this work is to represent principles of Carbon trading market, his function and historical development and connect them with possible advantages of Serbia's entry in the emission market

A New Approach in the Evaluation of Team Chess Championships Rankings

Classification method in a team chess championship has long been an issue of great concern. In quest of the golden standard," Chess Federation officials applied many different ranking methods. As part of the improvements," significant changes were introduced at the 2009 Serbia Team Chess Championship. In this paper, we will examine results of the 2008 and 2009 tournament by applying the statistical ranking method. Our aim was to compare classification in these two tournaments and for the first time quantitatively evaluate the rankings method in team chess championships. Some significant results were obtained during the process and we see them useful for the quality evaluation procedure of the classification methods. The correlation between 2008 Serbia Team Chess Championship ranking and the ranking based on the I-distance method was very significant with r=0.9639 and p

Emergency or Delayed Surgical Treatment of Unstable Supracondylar Humeral Fractures in Children?

Supracondylar humeral fractures (SCHF) are the most common elbow fractures in children, representing 3% of all paediatric fractures. Treatment options for SCHF in children are based on the Gartland classification. Treatment of non-displaced fractures (type I) is non-operative. Plaster immobilization for 3 to 4 weeks is recommended, depending on the age of the child and fracture healing. Treatments of displaced supracondylar fractures (type II and III) of the humerus in children are still undefined in clinical practice. Because of divided opinions, the aim of this study was to evaluate whether delayed or immediate surgical treatment has an advantage in the treatment of supracondylar fractures in children. This is a prospective – retrospective clinical study. This study included 64 patients from 5 to 15 years old; 47 (73.4%) were boys and 17 (26.6%) were girls. The most common age range (59.4%) in this study was 5-8 years old. All patients were diagnosed with supracondylar fractures at the Institute for Orthopaedic Surgery “Banjica”. We analysed 17 parameters, which were obtained either from direct patient interviews or from their medical history. All patients were divided into two groups with matched characteristics. Group I consisted of 26 patients who had immediate operations. Group II consisted of 38 patients who had delayed operations