282 research outputs found

    Dissecting phosphate signalling in Arabidopsis

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    FROM THE CONDUCTOR: A COMPILATION OF WIND BAND REPERTOIRE WITH REHEARSAL AND PERFORMANCE NOTES

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    The purpose of this thesis is to present a compilation of wind repertoire with detailed rehearsal and performance notes as it relates to conducting and rehearsing on a variety of different levels. The examined pieces will be A Festival Prelude by Alfred Reed, Spitfire! by Gary P. Gilroy, Chorale and Alleluia by Howard Hanson, Beyond the Summit by Brian Balmages, Sanctuary by Frank Ticheli, and Serenade No.1 for Ten Wind Instruments by Vincent Persichetti. Rehearsal notes will include teaching and conducting techniques used in the learning process while performance notes will include composer biographies and history pertaining to the pieces

    Visualizing practices in project-based design : tracing connections through cascades of visual representations

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    Project-based design involves a variety of visual representations, which are evolved to make decisions and accomplish project objectives. Yet, such mediated and distributed ways of working are difficult to capture through ethnographies that examine situated design. A novel approach is developed that follows cascades of visual representations; and this is illustrated through two empirical studies. In the first case, Heathrow Terminal 5, analysis starts from paper- and model-work used to develop design, tracing connections forward to an assembly manual that forms a ‘consolidated cascade ’ of visual representations . In th e second, the Turning Torso, Malmö, analysis starts from a planning document, trac ing connections backward to the paper - and model - work done to produce this consolidated cascade . Th is work makes a twofold contribution : First, it offer s a methodological app roach that supplements ethnographies of situated design. This allows the researcher to be nimble, tracing connections across complex engineering projects; reconstructing practices through their visual representations; and observing their effects. Second, it articulate s how , in these empirical cases, interaction with a cascade of visual representations enabled participants in project - based design to develop and share understanding. T he complexity of projects , and their distributed and mediated nature makes this approach timely and important in address ing new research questions and practical challenges

    Configuration Management in Complex Engineering Projects

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    AbstractDigital technologies are radically transforming project delivery, breaking the mould of 1960s approaches to enable more rapid and agile forms of organizing. Yet the use of large digital data-sets also requires new forms of control. This study compares the leading practices of managing change in digitally-enabled projects in Airbus, CERN and Crossrail. It focuses on configuration management, the process of maintaining system integrity while handling change to both the digital data-set and the related real- world engineering systems. The contribution is to explain: first, why configuration management has become more, rather than less, important in complex engineering in an era of ‘big data’; and second, how approaches to configuration management are shaped by these industrial contexts of civil engineering, nuclear research and aerospace. The paper concludes by considering the implications for managing digitally-enabled projects

    The effects of a graduated aerobic exercise programme on cardiovascular disease risk factors in the NHS workplace: a randomised controlled trial

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    BACKGROUND: Sufficient levels of physical activity provide cardio-protective benefit. However within developed society sedentary work and inflexible working hours promotes physical inactivity. Consequently to ensure a healthy workforce there is a requirement for exercise strategies adaptable to occupational time constraint. This study examined the effect of a 12 week aerobic exercise training intervention programme implemented during working hours on the cardiovascular profile of a sedentary hospital workforce. METHODS: Twenty healthy, sedentary full-time staff members of the North West London Hospital Trust cytology unit were randomly assigned to an exercise (n = 12; mean +/- SD age 41 +/- 8 years, body mass 69 +/- 12 kg) or control (n = 8; mean +/- SD age 42 +/- 8 years, body mass 69 +/- 12 kg) group. The exercise group was prescribed a progressive aerobic exercise-training programme to be performed 4 times a week for 8 weeks (initial intensity 65% peak oxygen consumption (VO2 peak)) and to be conducted without further advice for another 4 weeks. The control was instructed to maintain their current physical activity level. Oxygen economy at 2 minutes (2minVO2), 4 minutes (4minVO2), VO2 peak, systolic blood pressure (SBP), diastolic blood pressure (DBP), BMI, C-reactive protein (CRP), fasting glucose (GLU) and total cholesterol (TC) were determined in both groups pre-intervention and at 4 week intervals. Both groups completed a weekly Leisure Time Questionnaire to quantify additional exercise load. RESULTS: The exercise group demonstrated an increase from baseline for VO2 peak at week 4 (5.8 +/- 6.3 %) and 8 (5.0 +/- 8.7 %) (P < 0.05). 2minVO2 was reduced from baseline at week 4 (-10.2 +/- 10.3 %), 8 (-16.8 +/- 10.6 %) and 12 (-15.1 +/- 8.7 %), and 4minVO2 at week 8 (-10.7 +/- 7.9 %) and 12 (-6.8 +/- 9.2) (P < 0.05). There was also a reduction from baseline in CRP at week 4 (-0.4 +/- 0.6 mg.L-1) and 8 (-0.9 +/- 0.8 mg.L-1) (P < 0.05). The control group showed no such improvements. CONCLUSION: This is the first objectively monitored RCT to show that moderate exercise can be successfully incorporated into working hours, to significantly improve physical capacity and cardiovascular health
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