MOESM2 of Beyond type 2 diabetes, obesity and hypertension: an axis including sleep apnea, left ventricular hypertrophy, endothelial dysfunction, and aortic stiffness among Mexican Americans in Starr County, Texas

Additional file 2: Figure S1. Overlap of prediabetes classifications based on fasting blood glucose (100–125 mg/dl), 2-h post-load glucose (140–199 mg/dl and HbA1c (5.7–6.4 %) among Mexican Americans without diabetes in Starr County, Texas

Additional file 2: of Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos

Supplementary Figures. (DOCX 112 kb

Additional file 1: of Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos

Supplementary Tables. (ODS 129 kb

COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19

The COVID-19 pandemic continues to pose a major public health threat, especially in countries with low vaccination rates. To better understand the biological underpinnings of SARS-CoV-2 infection and COVID-19 severity, we formed the COVID-19 Host Genetics Initiative1. Here we present a genome-wide association study meta-analysis of up to 125,584 cases and over 2.5 million control individuals across 60 studies from 25 countries, adding 11 genome-wide significant loci compared with those previously identified2. Genes at new loci, including SFTPD, MUC5B and ACE2, reveal compelling insights regarding disease susceptibility and severity.</p