70 research outputs found

    Assessing the adoption of high iron bean varieties and their impact on iron intakes and other livelihood outcomes in Rwanda: Listing Exercise Report

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    An impact assessment (IA) study was conducted in Rwanda in 2015 Season B in order to establish the adoption rates of HIB varieties among rural bean producing and to generate useful information on delivery and breeding efforts by analyzing the facilitating/hindering factors to adoption and diffusion of HIB varieties. A nationally representative listing exercise preceded the main household survey for the impact assessment. The listing exercise was conducted across 120 rural villages in 29 provinces of Rwanda and was administered to a total of 19,575 households. The aims of the listing exercise were to determine the adoption rate of High Iron Beans (HIBs) and to inform second-stage sampling for the main impact assessment survey that was to follow. This report presents results from the listing exercise

    Selective Enhancement of Donor Hematopoietic Cell Engraftment by the CXCR4 Antagonist AMD3100 in a Mouse Transplantation Model

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    The interaction between stromal cell-derived factor-1 (SDF-1) with CXCR4 chemokine receptors plays an important role in hematopoiesis following hematopoietic stem cell transplantation. We examined the efficacy of post transplant administration of a specific CXCR4 antagonist (AMD3100) in improving animal survival and in enhancing donor hematopoietic cell engraftment using a congeneic mouse transplantation model. AMD3100 was administered subcutaneously at 5 mg/kg body weight 3 times a week beginning at day +2 post-transplant. Post-transplant administration of AMD3100 significantly improves animal survival. AMD3100 reduces pro-inflammatory cytokine/chemokine production. Furthermore, post transplant administration of AMD3100 selectively enhances donor cell engraftment and promotes recovery of all donor cell lineages (myeloid cells, T and B lymphocytes, erythrocytes and platelets). This enhancement results from a combined effect of increased marrow niche availability and greater cell division induced by AMD3100. Our studies shed new lights into the biological roles of SDF-1/CXCR4 interaction in hematopoietic stem cell engraftment following transplantation and in transplant-related mortality. Our results indicate that AMD3100 provides a novel approach for enhancing hematological recovery following transplantation, and will likely benefit patients undergoing transplantation

    Explaining Marketing Strategies among Bolivian Potato Farmers

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    Improving market access and promoting participation in more lucrative markets among semi-subsistence farming households is crucial for poverty alleviation. This paper analyzes joint decisions about market participation and market choices among Bolivian potato farmers. First, stochastic dominance analysis is used to identify market choices that have high pay-off and limited risk; these are referred to as optimal marketing strategies. Second, a system of equations is estimated to identify factors contributing or restricting market entry, volume sold, and adoption of optimal market-ing strategies. Proportional and fixed transaction costs reduce income-generating opportunities associated with markets for all three dimensions considered in this study. Our analysis also suggests the possible existence of poverty traps since fetching higher price requires liquidity and high volume, while land and farm equipment are needed to achieve necessary volumes of production

    IFAD RESERACH SERIES 64 - How the adoption of drought-tolerant rice varieties impacts households in a non-drought year: Evidence from Nepal

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    Stress-tolerant rice varieties (STRVs) are bred to be high yielding and tolerant to climate shocks such as drought. In Nepal, several drought-tolerant STRVs have been released and widely adopted. This paper estimates the impacts of the adoption of STRVs on first- and higher-order household outcomes in a non-drought year. It controls for selection bias using correlated random effects models to eliminate unobserved plot and household-level heterogeneity. STRVs have a higher yield, a lower yield variance and a shorter growing duration than traditional landrace varieties. In addition, households apply more early-season chemical fertilizer and land preparation labour to plots planted to STRVs compared to landraces. This indicates that the first-order impacts of the adoption of STRVs induce behavioural changes that help to modernize agricultural practices. Finally, this study conducts a randomized experiment in which half of the sampled households provided additional detail on their agricultural inputs
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