18 research outputs found

    Restless legs syndrome and health‐related quality of life in adults with multiple sclerosis

    Full text link
    Restless legs syndrome (RLS) is a sleep disorder that may exacerbate many of the symptoms and consequences of multiple sclerosis (MS), and may have further implications for health‐related quality of life (HRQOL). The present study examined the relationships among RLS, symptoms and HRQOL in people with MS. Participants with MS (n = 275) completed the Cambridge‐Hopkins Restless Legs Syndrome Questionnaire, the International Restless Legs Syndrome Study Group Scale, the Multiple Sclerosis Impact Scale, the Pittsburgh Sleep Quality Index, the Fatigue Severity Scale, the Hospital Anxiety and Depression Scale and the Patient Determined Disease Steps. There were 74 (26.9%) persons with MS who had RLS (MS + RLS). The MS + RLS group reported worse physical and psychological HRQOL (p = 0.020 and p = 0.017, respectively) and greater perceived fatigue (p = 0.006) and anxiety symptoms (p = 0.042) than the MS‐only group. Within the MS + RLS group, RLS severity was associated with physical (r = 0.43) and psychological (r = 0.46) HRQOL, sleep quality (r = 0.38), perceived fatigue (r = 0.28), depression (r = 0.38) and anxiety (r = 0.28). The relationships between RLS severity and the domains of HRQOL were attenuated when accounting for fatigue, depression and/or anxiety. Worse RLS severity was associated with reduced HRQOL, which was accounted for by fatigue, depression and anxiety.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155491/1/jsr12880.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155491/2/jsr12880_am.pd

    Physical activity, cardiorespiratory fitness, and metabolic syndrome in adolescents: A cross-sectional study

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>In adults, there is a substantial body of evidence that physical inactivity or low cardiorespiratory fitness levels are strongly associated with the development of metabolic syndrome. Although this association has been studied extensively in adults, little is known regarding this association in adolescents. The aim of this study was to analyze the association between physical activity and cardiorespiratory fitness levels with metabolic syndrome in Brazilian adolescents.</p> <p>Methods</p> <p>A random sample of 223 girls (mean age, 14.4 ± 1.6 years) and 233 boys (mean age, 14.6 ± 1.6 years) was selected for the study. The level of physical activity was determined by the Bouchard three-day physical activity record. Cardiorespiratory fitness was estimated by the Leger 20-meter shuttle run test. The metabolic syndrome components assessed included waist circumference, blood pressure, HDL-cholesterol, triglycerides, and fasting plasma glucose levels. Independent Student <it>t</it>-tests were used to assess gender differences. The associations between physical activity and cardiorespiratory fitness with the presence of metabolic syndrome were calculated using logistic regression models adjusted for age and gender.</p> <p>Results</p> <p>A high prevalence of metabolic syndrome was observed in inactive adolescents (males, 11.4%; females, 7.2%) and adolescents with low cardiorespiratory fitness levels (males, 13.9%; females, 8.6%). A significant relationship existed between metabolic syndrome and low cardiorespiratory fitness (OR, 3.0 [1.13-7.94]).</p> <p>Conclusion</p> <p>The prevalence of metabolic syndrome is high among adolescents who are inactive and those with low cardiorespiratory fitness. Prevention strategies for metabolic syndrome should concentrate on enhancing fitness levels early in life.</p

    Validation of the brazilian version of the patient-determined disease steps scale in persons with multiple sclerosis

    No full text
    The present study translated and adapted the Brazilian version of the Patient-Determined Disease Steps (PDDS) scale and tested its validity and reproducibility in Brazilian persons with multiple sclerosis (MS). The PDDS underwent translation and back-translation procedures for producing a Brazilian Portuguese version of the PDDS (PDDS/BR). Sixty-three patients with MS (48 females) completed the PDDS/BR and underwent a neurological examination for generation of Expanded Disability Status Scale (EDSS) scores. Participants further performed the following tests: Timed 25-Foot Walk (T25FW), Timed Up and Go (TUG), sixminute walk test (6MWT), Nine Hole Peg (9HPT), and Symbol Digit Modalities Test (SDMT). Construct validity of PDDS/BR scores was determined by Spearman correlation with EDSS, and comparison of correlations between PDDS/BR and EDSS with the functional tests. We examined overall correct classification of disability categories (i.e., mild, moderate, or severe disability) by the PDDS/BR in relation to the EDSS. Test-retest reproducibility of PDDS/BR scores was examined in a subsample of 31 participants after 15 days. There was a strong relationship between the PDDS/BR and EDSS scores (p = 0.723, p < 0.05). The correlations with TUG, T25FW, 6MWT, and 9HPT were comparable for the PDDS/BR and EDSS scores. Overall correct classification of disability categories by the PDDS/BR was 79.3%. Results indicated excellent test-retest reproducibility for the PDDS/BR (Intraclass Correlation Coefficient= 0.911, 95% CI: 0.685-0.918). The PDDS/BR scores provide a valid and reliable assessment of mobility disability and may be used by researchers and neurologists to assess disability status in Brazilians with MS30208214COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESnão te

    Use of the Godin leisure-time exercise questionnaire in multiple sclerosis research: a comprehensive narrative review

    No full text
    <p><b>Purpose:</b> The Godin Leisure-Time Exercise Questionnaire has been a commonly applied measure of physical activity in research among persons with multiple sclerosis over the past decade. This paper provides a comprehensive description of its application and inclusion in research on physical activity in multiple sclerosis.</p> <p><b>Method:</b> This comprehensive, narrative review included papers that were published between 1985 and 2017, written in English, involved participants with multiple sclerosis as a primary population, measured physical activity, and cited one of the two original Godin papers.</p> <p><b>Results and Conclusion:</b> There is a broad scope of research that has included the Godin Leisure-Time Exercise Questionnaire in persons with multiple sclerosis. Overall, 8 papers evaluated its psychometric properties, 21 evaluated patterns of physical activity, 24 evaluated correlates or determinants of physical activity, 28 evaluated outcomes or consequences of physical activity, and 15 evaluated physical activity interventions. The Godin Leisure-Time Exercise Questionnaire is a valid self-report measure of physical activity in persons with multiple sclerosis, and further is an appropriate, simple, and effective tool for describing patterns of physical activity, examining correlates and outcomes of physical activity, and provides a sensitive outcome for measuring change in physical activity after an intervention.Implications for rehabilitation</p><p>There is increasing interest in physical activity and its benefits in multiple sclerosis.</p><p>The study of physical activity requires appropriate and standardized measures.</p><p>The Godin Leisure-Time Exercise Questionnaire is a common self-report measure of physical activity for persons with multiple sclerosis.</p><p>Godin Leisure-Time Exercise Questionnaire scores are reliable measures of physical activity in persons with multiple sclerosis.</p><p>The Godin Leisure-Time Exercise Questionnaire further is an appropriate, simple, and effective tool for describing patterns of physical activity, examining correlates and outcomes of physical activity participation, and is an advantageous primary outcome for measuring change in physical activity in response to an intervention.</p><p></p> <p>There is increasing interest in physical activity and its benefits in multiple sclerosis.</p> <p>The study of physical activity requires appropriate and standardized measures.</p> <p>The Godin Leisure-Time Exercise Questionnaire is a common self-report measure of physical activity for persons with multiple sclerosis.</p> <p>Godin Leisure-Time Exercise Questionnaire scores are reliable measures of physical activity in persons with multiple sclerosis.</p> <p>The Godin Leisure-Time Exercise Questionnaire further is an appropriate, simple, and effective tool for describing patterns of physical activity, examining correlates and outcomes of physical activity participation, and is an advantageous primary outcome for measuring change in physical activity in response to an intervention.</p

    Can Sports Practice in Childhood and Adolescence Be Associated with Higher Intensities of Physical Activity in Adult Life? A Retrospective Study in Community-Dwelling Adults

    No full text
    Introduction: Investigating the determinants of physical activity (PA) is an important strategy for the promotion of healthy lifestyles, mainly with PA of a moderate-to-vigorous intensity, which provides several health benefits in adulthood. In this sense, it is not clear whether early sports practice (ESP) during childhood and adolescence could be associated with the habitual practice of PA of higher intensities in adulthood. Objective: This study aimed to analyze the association of ESP in childhood and adolescence with different intensities of habitual PA in adulthood. Methods: A sample of 264 community-dwelling adults were randomly selected (42.2 &plusmn; 17.0 years, 57.5% of women). ESP during childhood and adolescence was evaluated using retrospective questions. Weekly minutes of PA were assessed using accelerometry and classified according to intensity as light, moderate, moderate-to-vigorous, vigorous and very vigorous. The association of ESP with a high level of PA (above median) in each intensity was analyzed using binary regression models. Results: The prevalence of ESP was 42.8% in childhood and 49.2% in adolescence. ESP in childhood was associated with a high level of very vigorous (OR: 2.48, p &lt; 0.001) and vigorous PA (OR: 2.91, p &lt; 0.001) in adulthood, but lost significance after adjustments by sex and age. ESP in adolescence was associated with a high level of very vigorous PA (OR: 1.99, p = 0.013) in the crude model and vigorous PA (OR: 2.21, p = 0.006), even after adjustments by age, sex and socioeconomic status. Conclusions: Engagement in sports practice during adolescence was associated with high levels of vigorous PA in adulthood and is an important period for healthy lifestyle promotion
    corecore