Gingival cyst of the adult in a pediatric patient: Report of a case

Although the gingival cyst of the adult is considered rare in children, it can occur. The GCA can cause necrosis of the alveolar bone if untreated and should be considered in the differential diagnosis of raised gingival lesions.Although the gingival cyst of the adult is considered rare in children, it can occur. The GCA can cause necrosis of the alveolar bone if untreated and should be considered in the differential diagnosis of raised gingival lesions.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154395/1/ccr32646.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154395/2/ccr32646_am.pd

Spike: Artificial intelligence scheduling for Hubble space telescope

Efficient utilization of spacecraft resources is essential, but the accompanying scheduling problems are often computationally intractable and are difficult to approximate because of the presence of numerous interacting constraints. Artificial intelligence techniques were applied to the scheduling of the NASA/ESA Hubble Space Telescope (HST). This presents a particularly challenging problem since a yearlong observing program can contain some tens of thousands of exposures which are subject to a large number of scientific, operational, spacecraft, and environmental constraints. New techniques were developed for machine reasoning about scheduling constraints and goals, especially in cases where uncertainty is an important scheduling consideration and where resolving conflicts among conflicting preferences is essential. These technique were utilized in a set of workstation based scheduling tools (Spike) for HST. Graphical displays of activities, constraints, and schedules are an important feature of the system. High level scheduling strategies using both rule based and neural network approaches were developed. While the specific constraints implemented are those most relevant to HST, the framework developed is far more general and could easily handle other kinds of scheduling problems. The concept and implementation of the Spike system are described along with some experiments in adapting Spike to other spacecraft scheduling domains

Consumer demand for sustainable wildcaught and cultured live reef food fish in Hong Kong

Live reef food fish (LRFF) is a popular dish in Hong Kong and the southern parts of China. The production of LRFF provides a valuable source of income for many coastal communities in AsiaPacific countries. However, overexploitation and destructive fishing practices lead to questions about the sustainability of the LRFF trade. There are two ways of solving the problem. The first is managing the LRFF fishery in a sustainable way. Another is supplying LRFF from hatcherybased aquaculture. However, the acceptability of cultured LRFF and the premium that consumers are willing to pay for LRFF from sustainable sources are largely unknown. This research applies a nonmarket valuation technique, discrete choice modelling, to estimate the willingness to pay (WTP) of Hong Kong consumers for sustainably sourced LRFF, and the difference in WTP between wild fish and cultured fish of four popular species: Humphead Wrasse (Ceilinus undulatus), Humpback Grouper (Cromiletus altivelis), Leopard Coralgrouper (Plectropomus leopardus) and Tiger Grouper (Epinephelus fuscoguttatus). The research results show that if Hong Kong consumers are provided with environmental information to guide their consumer choices, it is estimated that they would be willing to pay an average of HK$25.69 per tael for LRFF which come from a sustainable, rather than an unsustainable source of supply. Also, the premium that consumers are willing to pay for wild fish over cultured fish is estimated HK$12.76 per tael on average. These results indicate that there is a potentially strong commercial incentive to source live reef fish from sustainable fisheries. Secondly, while there appears to be a strong consumer preference for wildcaught over aquaculture live reef fish, it is not known whether this preference difference is real or perceived. As consumers become more familiar with aquaculture product, the implied discount in price for aquaculture compared to wildcaught product may diminish. The limited consumer tasting research conducted to date indicates that the aquaculture product is likely to be highly acceptable (Chan 2006). Policies to engage consumers and restaurants in the acceptance of cultured LRFF as an alternative to wildcaught fish and the environmental issues associated with current LRFF production practices would be beneficial to the long term sustainability of the LRFF trade in the AsiaPacific region

Do Generic Health and Population Norm Based Outcomes Adequately Detect Change in Patients Attending Outpatient Physical Therapy?

The purpose was to determine the ability of Patient Reported Outcome Measurement Information (PROMIS) Pain Interference (PI), Physical Function (PF), Fatigue, and Self-Efficacy of Symptom Management (SE) scales to detect change and outcomes compared to population norms at discharge from an outpatient orthopedic clinic

A Study on the Tendency of the Environmental Education in Geography Text-book of the World

1.帝国書院から翻訳出版された世界地理教科書全30巻を通読し, そのなかから国情の差と世界全域を網羅することを考慮して23ヶ国を選び, 地理教育における環境教育の一側面を捉える試みを行った.2.対象とした各国の教科書は, それぞれの国の教育制度, 教育年限, 教育事情が異なるため, 対象年令が若干異なっているが, 一部を除き大半は中等教育以上の教科書である.次代を教育する教科書という共通の基盤にたつものと理解して, 以下の調査を行い若干の知見を得た.3.各国の地理教科書から環境と人間活動とに係る環境問題に関する記述を抽出してまず記述量を把握し, 次いで記述の対象について13項目に分け, さらに42の細目に分類整理した.その結果は第1図, 第2表, 第4表に示した.4.抽出した記述量は全体で566記述, 単純な一国平均は25記述となり, 最高記述国は56記述のアメリカ合衆国であった.5.さらに記述量が多い項目第1位と第2位を基にして, 各国の特色を把握し第3表のような5グループに分類した.6. 42種に細分した記述からは, 各国それぞれの環境問題に対する関心の領域の広狭をうかがうことができるが, 最も広範にわたって記述している国は記述量でも多いアメリカ合衆国であった.7.記述量と記述細目数とを基にすると地理教育の分野で, 環境教育問題に関心を寄せている国とさほどではない国とに分かれる.関心が高い国と察知されるのは, アメリカ合衆国, フランス, オーストラリアなど10ヶ国であった.8.環境教育問題は, 執筆形式にもよるが, 単元 (章) や節を直接設けている関心が高い国は, 第5表のとおり10ヶ国見られた.9.環境教育の方法, 環境問題の中心に取り上げられている課題あるいは視点は, 国情によってIn this study, we made it clear that tendency of environmental education in the geography textbook of the world. We used textbooks in Japanese translation of each country languages and these textbooks timely published by the Teikoku-Shoin from 1979 to 1980. The method of study is as follows. The environmental problems such as natural conservation and environment, various field of industry, various kinds of industrial pollution, living environment, outdoor recreation and other things are extracted from the discription in textbooks. We counted out the number of extracted data each country and matters for investigation and made a surveyed of its character in the same time. These data was classified into thirteen groups according to the same factor and subdivided into forty two items such as protection and conservation area, pollution, natural resources, living environment, municipal waste, land development and other things. A summary of the survey is shown below. 1) The count of environmental discription in each country range from the most fifty three in U. S. A. to the lowest five in Mexco and Brazil and its average twenty five. 2) As we cannot easily compare with that each country has its own writing style of textbook, it was ten countries that take up a environmental problems by chapter or section on the textbook. 3) Each country it different from politic and economic situation, framework of society, standard of land development and living and so on. The character of each country from a point of view environmental problems and its education can be broadly classified into five group. 4) Moreover, we was classified by character of environmental education as developed country and developing country and the former may be divied into a narrow, overpopulated old country and a wide, abundant in natural resources newer country

Regulation of Muscle Satellite Cell Activation and Chemotaxis by Angiotensin II

The role of angiotensin II (Ang II) in skeletal muscle is poorly understood. We report that pharmacological inhibition of Ang II signaling or ablation of the AT1a receptor significantly impaired skeletal muscle growth following myotrauma, in vivo, likely due to impaired satellite cell activation and chemotaxis. In vitro experiments demonstrated that Ang II treatment activated quiescent myoblasts as evidenced by the upregulation of myogenic regulatory factors, increased number of β-gal+, Myf5-LacZ myoblasts and the acquisition of cellular motility. Furthermore, exogenous treatment with Ang II significantly increased the chemotactic capacity of C2C12 and primary cells while AT1a−/− myoblasts demonstrated a severe impairment in basal migration and were not responsive to Ang II treatment. Additionally, Ang II interacted with myoblasts in a paracrine-mediated fashion as 4 h of cyclic mechanical stimulation resulted in Ang II-induced migration of cocultured myoblasts. Ang II-induced chemotaxis appeared to be regulated by multiple mechanisms including reorganization of the actin cytoskeleton and augmentation of MMP2 activity. Collectively, these results highlight a novel role for Ang II and ACE inhibitors in the regulation of skeletal muscle growth and satellite cell function

Support-seeking by cancer caregivers living in rural Australia

Objective: Rural cancer caregivers report poor wellbeing and high unmet needs for support. This study investigates sources of support sought by cancer caregivers living in rural Australia, and factors associated with support-seeking. Methods: Informal caregivers of people with cancer completed a questionnaire assessing sociodemographic characteristics, caregiver factors and support-seeking. Descriptive statistics, bivariate analyses and logistic regression were used to identify common sources of support and factors associated with support-seeking. Alluvial and radar plots were used to identify and describe support-seeking profiles. Findings: Of 244 rural caregivers, 64 % reported seeking support for themselves, 72 % for the cancer patient, and 22 % did not seek any support. The most common sources of support were general practitioners and online. Higher caregiver burden, higher income, caring for someone with anxiety/depression or caring for someone who has difficulty completing their usual activities were associated with seeking support from a greater number of sources. The ‘No support-seekers’ profile had the highest proportions of caregivers who were male, caring for someone \u3c 12 months post-diagnosis and lower income earners. Conclusions: Many rural caregivers seek support for themselves and the cancer patient, commonly from medical and online sources. Implications for public health: Further work may be needed to reduce caregiver burden and support caregivers who are male, caring for someone recently diagnosed, and those with lower incomes

Combinations of idelalisib with rituximab and/or bendamustine in patients with recurrent indolent non-Hodgkin lymphoma

Key Points Combining phosphatidylinositol-3-kinase δ inhibition with rituximab, bendamustine, or both is feasible and active in relapsed iNHL. The safety of novel combinations should be proven in phase 3 trials before adoption in clinical practice.</jats:p

The Effect of Diet and Exercise Interventions on Body Composition in Liver Cirrhosis: A Systematic Review

Alterations in body composition, in particular sarcopenia and sarcopenic obesity, are complications of liver cirrhosis associated with adverse outcomes. This systematic review aimed to evaluate the effect of diet and/or exercise interventions on body composition (muscle or fat) in adults with cirrhosis. Five databases were searched from inception to November 2021. Controlled trials of diet and/or exercise reporting at least one body composition measure were included. Single-arm interventions were included if guideline-recommended measures were used (computed tomography/magnetic resonance imaging, dual-energy X-ray absorptiometry, bioelectrical impedance analysis, or ultrasound). A total of 22 controlled trials and 5 single-arm interventions were included. Study quality varied (moderate to high risk of bias), mainly due to lack of blinding. Generally, sample sizes were small (n = 6–120). Only one study targeted weight loss in an overweight population. When guideline-recommended measures of body composition were used, the largest improvements occurred with combined diet and exercise interventions. These mostly employed high protein diets with aerobic and or resistance exercises for at least 8 weeks. Benefits were also observed with supplementary branched-chain amino acids. While body composition in cirrhosis may improve with diet and exercise prescription, suitably powered RCTs of combined interventions, targeting overweight/obese populations, and using guideline-recommended body composition measures are needed to clarify if sarcopenia/sarcopenic obesity is modifiable in patients with cirrhosis