8 research outputs found

    Surface Ocean Dispersion Observations From the Ship-Tethered Aerostat Remote Sensing System

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    Oil slicks and sheens reside at the air-sea interface, a region of the ocean that is notoriously difficult to measure. Little is known about the velocity field at the sea surface in general, making predictions of oil dispersal difficult. The Ship-Tethered Aerostat Remote Sensing System (STARSS) was developed to measure Lagrangian velocities at the air-sea interface by tracking the transport and dispersion of bamboo dinner plates in the field of view of a high-resolution aerial imaging system. The camera had a field of view of approximately 300 × 200 m and images were obtained every 15 s over periods of up to 3 h. A series of experiments were conducted in the northern Gulf of Mexico in January-February 2016. STARSS was equipped with a GPS and inertial navigation system (INS) that was used to directly georectify the aerial images. A relative rectification technique was developed that translates and rotates the plates to minimize their total movement from one frame to the next. Rectified plate positions were used to quantify scale-dependent dispersion by computing relative dispersion, relative diffusivity, and velocity structure functions. STARSS was part of a nested observational framework, which included deployments of large numbers of GPS-tracked surface drifters from two ships, in situ ocean measurements, X-band radar observations of surface currents, and synoptic maps of sea surface temperature from a manned aircraft. Here we describe the STARSS system and image analysis techniques, and present results from an experiment that was conducted on a density front that was approximately 130 km offshore. These observations are the first of their kind and the methodology presented here can be adopted into existing and planned oceanographic campaigns to improve our understanding of small-scale and high-frequency variability at the air-sea interface and to provide much-needed benchmarks for numerical simulations

    HCVerso2: a phase III study of faldaprevir plus deleobuvir and ribavirin for chronic HCV genotype 1b infection in treatment naïve patients including those ineligible for pegylated interferon

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    peer reviewedIn treatment-naïve, non-cirrhotic patients with HCV GT1b infection, faldaprevir + deleobuvir + ribavirin for 16 or 24 w resulted in comparable SVR 12 rates (76% vs 82%) with similar tolerability profiles. Patients with cirrhosis achieved SVR 12 of 74% (24w). The adjusted SVR rates for 16 or 24w in patients with or without cirrhosis were significantly higher than historical control

    Seasonality of the submesoscale dynamics in the Gulf Stream region

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    Frontogenesis and frontal instabilities in the mixed layer are known to be important processes in the formation of submesoscale features. We study the seasonality of such processes in the Gulf Stream (GS) region. To approach this problem, a realistic simulation with the Hybrid Coordinate Ocean Model is integrated for 18 months at two horizontal resolutions: a high-resolution (1/48°) simulation able to resolve part of the submesoscale regime and the full range of mesoscale dynamics, and a coarser resolution (1/12°) case, in which submesoscales are not resolved. Results provide an insight into submesoscale dynamics in the complex GS region. A clear seasonal cycle is observed, with submesoscale features mostly present during winter. The submesoscale field is quantitatively characterized in terms of deviation from geostrophy and 2D dynamics. The limiting and controlling factor in the occurrence of submesoscales appears to be the depth of the mixed layer, which controls the reservoir of available potential energy available at the mesoscale fronts that are present most of the year. Atmospheric forcings are the main energy source behind submesoscale formation, but mostly indirectly through mixed layer deepening. The mixed layer instability scaling suggested in the (Fox-Kemper et al., J Phys Oceanogr 38:1145–1165, 2008) parametrization appears to hold, indicating that the parametrization is appropriate even in this complex and mesoscale dominated area
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