The Opening Ceremony of the Radiopharmaceuticals Production and Research Centre at the Heavy Ion Laboratory of the University of Warsaw, May 15, 2012 Followed by an International Conference PETRAD2012

Two important events happened at the Heavy Ion Laboratoryof the University of Warsaw in May this year. First, on May 15 thenew Radiopharmaceuticals Production and Research Centre(RPRC) was inaugurated by the Rector Elect, Prof. Marcin Pałys.The construction of this Centre, located on the premises of theLaboratory, was supported by grants from the Ministry of Sciences,International Atomic Energy Agency, Ministry of Health and EuropeanStructural Funds

Nuclear surface studies with antiprotonic atom X-rays

The recent and older level shifts and widths in pbar atoms are analyzed. The results are fitted by an antiproton-nucleus optical potential with two basic complex strength parameters. These parameters are related to average S and P wave scattering parameters in the subthreshold energy region. A fair consistency of the X-ray data for all Z values, stopping pbar data and the Nbar-N scattering data has been achieved. The determination of neutron density profiles at the nuclear surface is undertaken, and the determination of the neutron R_{rms} radii is attempted. Uncertainties due to the input data and the procedure are discussed.Comment: 13 pages, 6 tables, 3 figure

Information on the nuclear periphery from antiprotonic atoms

In the PS209 experiments at CERN two kinds of measurements were performed: the in-beam measurement of X-rays from antiprotonic atoms and the radiochemical, off-line determination of the yield of annihilation products with mass number At — 1 (less by 1 than the target mass). Both methods give observables which allows to study the peripheral matter density composition and distribution. A comparisons of the PS209 results with the theoretical and semiempirical predictions for neutron and proton densities and with the differences Arnp of the rms radii of neutrons and protons obtained in other experiments are also presented

Medical Radioisotopes Produced with Cyclotron Beams in Warsaw

The various production routes of the prospective medical radioisotopes 43Sc, 44gSc, 44mSc, 47Sc, 44Ti/44gSc, 99mTc, 72Se/72As and 211At were investigated by a team from the Heavy Ion Laboratory, University of Warsaw (HIL-UW), the University of Silesia (US) and the National Centre for Nuclear Research (NCNR). Three cyclotrons were employed: the K=160 heavy-ion cyclotron with an internal 32 MeV alpha particle beam and the p/d PETtrace medical cyclotron at HIL and the C30 proton cyclotron at NCNR in Świerk, near Warsaw. The Thick Target Yields, activity at the End of Bombardment (EOB) and the impurities produced in addition to the main isotope are reported. The possible medical applications of these radioisotopes are briefly discussed

Metabolic control level and glucose variability in adolescents with type 1 diabetes during low and high-intensity exercise

OBJECTIVE The main purpose of this study was to characterize the determinants of metabolic changes in young type 1 diabetes (T1DM) and to determine glycemic variability during low and high-intensity exercise. PATIENTS AND METHODS 20 young male T1DM patients were divided into two subgroups characterized by levels of glycated hemoglobin (HbA1c): HbA1c7.3% (worse HbA1c subgroup, n=10). All participants performed a maximal oxygen uptake test and two efforts of various intensities (45 minutes of aerobic exercise and 30 minutes of mixed aerobic-anaerobic intensity exercise). Continuous glucose monitors (CGM) were used to control the glucose concentration. RESULTS Changes in biomarkers describing the metabolic response were similar in both groups. A comparison of applied efforts exhibited that maximal capacity effort resulted in the highest values of blood glucose (BG) at the end (150.9-160.6 mg/dl) and 1 hour after the exercise (140.2-161.3 mg/dl). BG concentration before, during, 1 hour, and 24 hours after each exercise was insignificantly higher in the worse Hb1Ac group. CONCLUSIONS HbA1c levels are insufficient to confirm whether the applied effort is performed in acceptable glycemic values. The CGM monitors allow for precise control of BG variations and accurate planning of physical activity by adjusting the insulin and carbohydrate consumption dose

Medical radioisotopes produced using the alpha particle beam from the Warsaw Heavy Ion Cyclotron

The internal alpha particle beam of the heavy ion cyclotron operated by the Heavy Ion Laboratory (HIL) of the University of Warsaw has a maximum energy of 32 MeV and currently an intensity of up to 1 p A. This beam is used by the HIL-University of Silesia collaboration for the production of research quantities of 211At, 72Se/72As and 43;44Sc radioisotopes. The produced activities are transported to the Institute of Nuclear Chemistry and Technology inWarsaw where research on therapeutic and imaging radiopharmaceuticals based on these radioisotopes is pursued